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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07146646 | RECRUITING | PHASE2
27 Participants

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2027-02-28
Conditions
Biliary Tract Cancer Biliary Tract Neoplasms Cholangiocarcinoma Gallbladder Cancer Gallbladder Carcinoma
Interventions
DRUG
No Results Yet
NCT07145918 | RECRUITING | PHASE2
258 Participants

A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-04
Completion: 2028-02-29
Conditions
Schizophrenia
Interventions
DRUG
No Results Yet
NCT07144826 | NOT_YET_RECRUITING | EARLY_PHASE1
161 Participants

Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-09
Completion: 2027-07-09
Conditions
Advanced Ovarian Carcinoma Recurrent Ovarian Carcinoma Stage II Ovarian Cancer AJCC v8 Stage III Ovarian Cancer AJCC v8 Stage IV Ovarian Cancer AJCC v8
Interventions
PROCEDURE DRUG DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT07144631 | RECRUITING | NA
15 Participants

Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-15
Completion: 2026-09-30
Conditions
Restless Leg Disorder Restless Leg Syndrome (RLS) Pregnancy Sleep Disorder (Disorder)
Interventions
DEVICE
No Results Yet
NCT07142811 | RECRUITING | PHASE2
100 Participants

A Study to Evaluate Tobevibart+Elebsiran Versus Bulevirtide in Chronic HDV Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-05
Completion: 2026-11-30
Conditions
Viral Hepatitis
Interventions
DRUG
No Results Yet
NCT07142343 | RECRUITING | PHASE4
5 Participants

A Study to Test the Safety of Pozelimab in Pediatric Participants 1 to 5 Years of Age With a Rare Disease Called CHAPLE (Complement Hyperactivation, Angiopathic Thrombosis, Protein-losing Enteropathy) Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-23
Completion: 2029-08-24
Conditions
CHAPLE Disease
Interventions
DRUG
No Results Yet
NCT07133633 | RECRUITING | PHASE2
315 Participants

A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-26
Completion: 2027-06-15
Conditions
Radiographic Axial Spondyloarthritis
Interventions
DRUG
No Results Yet
NCT07128901 | NOT_YET_RECRUITING | NA
6 Participants

Lower-Limb Exoskeleton Technology for Non-Ambulatory Individuals With Spinal Cord Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-01
Completion: 2026-12-01
Conditions
Spinal Cord Injuries
Interventions
DEVICE
No Results Yet
NCT07128628 | NOT_YET_RECRUITING | PHASE2
423 Participants

A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-30
Completion: 2026-11-30
Conditions
Dry Eye Disease
Interventions
DRUG
No Results Yet
NCT07128550 | RECRUITING | PHASE3
150 Participants

A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-30
Completion: 2026-12-31
Conditions
Viral Hepatitis
Interventions
DRUG
No Results Yet
NCT07128303 | RECRUITING | PHASE1
178 Participants

Study of GS-5319 in Adults With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-28
Completion: 2028-05-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT07125326 | NOT_YET_RECRUITING | NA
564 Participants

How the Method of Bladder Emptying After Epidural Placement in Labor Affects Postpartum Voiding

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-30
Completion: 2026-08-31
Conditions
Urinary Retention Urinary Tract Infection (Diagnosis) Postpartum Acute Urinary Retention Postpartum Care Voiding Dysfunction
Interventions
PROCEDURE
No Results Yet
NCT07125027 | RECRUITING | NA
32 Participants

A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-15
Completion: 2026-11-30
Conditions
Lumbosacral Radiculopathy Sciatica Chronic Low Back Pain With a Neuropathic Component Radiculopathy Lumbar Chronic Pain (Back / Neck)
Interventions
BEHAVIORAL
No Results Yet
NCT07117136 | RECRUITING
200 Participants

Blinatumomab Consolidation in Real World

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-28
Completion: 2029-05-14
Conditions
B-Cell Acute Lymphoblastic Leukaemia
No Results Yet
NCT07116226 | ENROLLING_BY_INVITATION | NA
40 Participants

Learning How to Implement and Use a Ketogenic Diet to Improve Mental Health

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-01
Completion: 2025-12-01
Conditions
Medical Keto Diet
Interventions
OTHER
No Results Yet
NCT07111182 | RECRUITING | NA
8 Participants

Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-27
Completion: 2027-11-30
Conditions
Brain Neoplasms
Interventions
DEVICE
No Results Yet
NCT07111052 | RECRUITING | NA
50 Participants

Lock and Protect: Reducing Adolescent Access to Lethal Means of Suicide

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-11
Completion: 2026-12-31
Conditions
Suicide Suicide Attempt Adolescent Suicidality Suicide Ideation
Interventions
BEHAVIORAL
No Results Yet
NCT07110246 | RECRUITING | PHASE2
96 Participants

Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-07
Completion: 2032-03-31
Conditions
BRAF V600 Mutation Low-grade Glioma Low Grade Glioma of Brain Recurrent Low Grade Glioma
Interventions
DRUG PROCEDURE
No Results Yet
NCT07102394 | NOT_YET_RECRUITING | PHASE1
10 Participants

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-02-01
Completion: 2026-12-31
Conditions
NF1 Neurofibromatosis Cutaneous Neurofibroma Neurofibroma Von Recklinghausen Disease Neurofibromas
Interventions
DRUG
No Results Yet
NCT07101289 | RECRUITING | NA
900 Participants

Eat Well Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-22
Completion: 2026-12-31
Conditions
Congestive Heart Failure Chronic
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07100080 | RECRUITING | PHASE2/PHASE3
596 Participants

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-05
Completion: 2028-09-15
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT07098364 | RECRUITING | PHASE1/PHASE2
33 Participants

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2030-10-04
Conditions
Recurrent Diffuse Large B-Cell Lymphoma Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Recurrent Grade 3b Follicular Lymphoma Recurrent High-Grade B-Cell Lymphoma Recurrent Indolent B-Cell Non-Hodgkin Lymphoma Recurrent Primary Mediastinal Large B-Cell Lymphoma Refractory Diffuse Large B-Cell Lymphoma Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Refractory Grade 3b Follicular Lymphoma Refractory High-Grade B-Cell Lymphoma Refractory Indolent B-Cell Non-Hodgkin Lymphoma Refractory Primary Mediastinal Large B-Cell Lymphoma
Interventions
PROCEDURE BIOLOGICAL
No Results Yet
NCT07097506 | RECRUITING | PHASE2
40 Participants

Effect of Ketone Esters on Liver Fat Content and Metabolic Function

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-26
Completion: 2027-07-31
Conditions
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease Obesity Overweight (BMI > 25)
Interventions
DRUG OTHER
No Results Yet
NCT07095556 | RECRUITING | NA
39 Participants

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-05
Completion: 2026-12-31
Conditions
Wound Healing and Prevention Oral Inflammation Photobiomodulation Post-operative Pain Management Tooth Extraction Site Healing
Interventions
OTHER
No Results Yet
NCT07092865 | RECRUITING | PHASE2
208 Participants

A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-06
Completion: 2027-01-12
Conditions
Respiratory Syncytial Virus Infections
Interventions
BIOLOGICAL
No Results Yet
NCT07091695 | COMPLETED
100 Participants

Real-world Outcomes Among Patients With Melanoma Treated With Neoadjuvant Nivolumab+Relatlimab or Nivolumab+Ipilimumab

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-11
Completion: 2025-11-06
Conditions
Melanoma
Interventions
BIOLOGICAL
No Results Yet
NCT07086976 | RECRUITING | PHASE3
90 Participants

A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-18
Completion: 2028-05-31
Conditions
Autoimmune Haemolytic Anaemia
Interventions
DRUG
No Results Yet
NCT07085338 | RECRUITING | PHASE2
54 Participants

A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-10
Completion: 2028-02-01
Conditions
Neuroblastoma Recurrent
Interventions
DRUG
No Results Yet
NCT07085325 | NOT_YET_RECRUITING
184 Participants

CSIMEMPHIS: Long-term Follow-up of Medulloblastoma Survivors That Received Craniospinal Irradiation

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2030-10-31
Conditions
Medulloblastoma
No Results Yet
NCT07084168 | RECRUITING | NA
30 Participants

Multimedia Aid for Genetic Testing in Gynecologic Oncology

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-10
Completion: 2026-10-30
Conditions
Ovary Cancer Endometrial Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT07076485 | RECRUITING | PHASE2
768 Participants

Shortening Adjuvant Photon and Proton Irradiation (SAPPHIRe-II): A 4 Cohort, Randomized, Phase II Multi-center Trial Evaluating Shorter Schedules of Adjuvant Regional Nodal Irradiation Among Women and Men With Node-positive and High-risk Node-negative Invasive Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-19
Completion: 2029-01-01
Conditions
Breast Cancer
Interventions
RADIATION
No Results Yet
NCT07076212 | RECRUITING | PHASE2
52 Participants

Evaluating NALIRIFOX vs Modified Gemcitabine, Nab-Paclitaxel and Cisplatin in Patients With Locally Advanced and Metastatic Pancreatic Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-07
Completion: 2028-05-31
Conditions
Metastatic Pancreatic Adenocarcinoma Locally Advanced Pancreatic Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT07071623 | RECRUITING | PHASE3
4580 Participants

A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-10
Completion: 2027-10-18
Conditions
Human Immunodeficiency Virus (HIV) HIV Pre-Exposure Prophylaxis
Interventions
DRUG
No Results Yet
NCT07071519 | RECRUITING | PHASE3
120 Participants

A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-28
Completion: 2034-07-31
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
NCT07065240 | RECRUITING | PHASE2
360 Participants

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-06-19
Completion: 2027-03-31
Conditions
Major Depressive Disorder (MDD) Major Depressive Disorder With Anxious Distress
Interventions
DRUG
No Results Yet
NCT07064473 | RECRUITING | PHASE3
11800 Participants

A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-22
Completion: 2029-12-14
Conditions
Diabetes Mellitus, Type 2 Hypertension Cardiovascular Diseases
Interventions
DRUG
No Results Yet
NCT07063745 | RECRUITING | PHASE2/PHASE3
590 Participants

A Study to Compare the Combination of BMS-986504 With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-28
Completion: 2031-08-12
Conditions
Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Interventions
DRUG OTHER
No Results Yet
NCT07063654 | COMPLETED | NA
17 Participants

Mobile Health Program for Teens With Congenital Heart Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-17
Completion: 2025-11-02
Conditions
Congenital Heart Disease in Adolescence Health Behavior
Interventions
BEHAVIORAL
No Results Yet
NCT07061977 | RECRUITING | PHASE3
336 Participants

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-05
Completion: 2030-12-31
Conditions
Locally Advanced Cervical Adenocarcinoma Locally Advanced Cervical Adenosquamous Carcinoma Locally Advanced Cervical Squamous Cell Carcinoma Stage IIIA Cervical Cancer FIGO 2018 Stage IIIB Cervical Cancer FIGO 2018 Stage IIIC1 Cervical Cancer FIGO 2018 Stage IIIC2 Cervical Cancer FIGO 2018 Stage IVA Cervical Cancer FIGO 2018
Interventions
PROCEDURE RADIATION DRUG BIOLOGICAL
No Results Yet
NCT07061964 | RECRUITING | PHASE2
111 Participants

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-06-01
Completion: 2027-07-31
Conditions
Muscle Invasive Bladder Urothelial Carcinoma Stage II Bladder Cancer AJCC v8 Stage IIIA Bladder Cancer AJCC v8
Interventions
PROCEDURE BIOLOGICAL RADIATION OTHER
No Results Yet
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