Clinical Trials
Showing trials with last updates posted in 2025.
6
Participants
Lower-Limb Exoskeleton Technology for Non-Ambulatory Individuals With Spinal Cord Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2026-01-01
Completion:
2026-12-01
Conditions
Spinal Cord Injuries
Interventions
DEVICE
No Results Yet
423
Participants
A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-30
Completion:
2026-11-30
Conditions
Dry Eye Disease
Interventions
DRUG
No Results Yet
150
Participants
A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-30
Completion:
2026-12-31
Conditions
Viral Hepatitis
Interventions
DRUG
No Results Yet
178
Participants
Study of GS-5319 in Adults With Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-28
Completion:
2028-05-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
564
Participants
How the Method of Bladder Emptying After Epidural Placement in Labor Affects Postpartum Voiding
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-30
Completion:
2026-08-31
Conditions
Urinary Retention
Urinary Tract Infection (Diagnosis)
Postpartum Acute Urinary Retention
Postpartum Care
Voiding Dysfunction
Interventions
PROCEDURE
No Results Yet
32
Participants
A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-15
Completion:
2026-11-30
Conditions
Lumbosacral Radiculopathy
Sciatica
Chronic Low Back Pain With a Neuropathic Component
Radiculopathy Lumbar
Chronic Pain (Back / Neck)
Interventions
BEHAVIORAL
No Results Yet
200
Participants
Blinatumomab Consolidation in Real World
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-28
Completion:
2029-05-14
Conditions
B-Cell Acute Lymphoblastic Leukaemia
No Results Yet
40
Participants
Learning How to Implement and Use a Ketogenic Diet to Improve Mental Health
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-01
Completion:
2025-12-01
Conditions
Medical Keto Diet
Interventions
OTHER
No Results Yet
8
Participants
Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-10-27
Completion:
2027-11-30
Conditions
Brain Neoplasms
Interventions
DEVICE
No Results Yet
50
Participants
Lock and Protect: Reducing Adolescent Access to Lethal Means of Suicide
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-11
Completion:
2026-12-31
Conditions
Suicide
Suicide Attempt
Adolescent Suicidality
Suicide Ideation
Interventions
BEHAVIORAL
No Results Yet
96
Participants
Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-07
Completion:
2032-03-31
Conditions
BRAF V600 Mutation
Low-grade Glioma
Low Grade Glioma of Brain
Recurrent Low Grade Glioma
Interventions
DRUG
PROCEDURE
No Results Yet
10
Participants
Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2026-02-01
Completion:
2026-12-31
Conditions
NF1
Neurofibromatosis
Cutaneous Neurofibroma
Neurofibroma
Von Recklinghausen Disease
Neurofibromas
Interventions
DRUG
No Results Yet
900
Participants
Eat Well Heart Failure
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-10-22
Completion:
2026-12-31
Conditions
Congestive Heart Failure Chronic
Interventions
BEHAVIORAL
OTHER
No Results Yet
596
Participants
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-05
Completion:
2028-09-15
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
33
Participants
ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2030-10-04
Conditions
Recurrent Diffuse Large B-Cell Lymphoma
Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Recurrent Grade 3b Follicular Lymphoma
Recurrent High-Grade B-Cell Lymphoma
Recurrent Indolent B-Cell Non-Hodgkin Lymphoma
Recurrent Primary Mediastinal Large B-Cell Lymphoma
Refractory Diffuse Large B-Cell Lymphoma
Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Refractory Grade 3b Follicular Lymphoma
Refractory High-Grade B-Cell Lymphoma
Refractory Indolent B-Cell Non-Hodgkin Lymphoma
Refractory Primary Mediastinal Large B-Cell Lymphoma
Interventions
PROCEDURE
BIOLOGICAL
No Results Yet
40
Participants
Effect of Ketone Esters on Liver Fat Content and Metabolic Function
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-26
Completion:
2027-07-31
Conditions
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Obesity
Overweight (BMI > 25)
Interventions
DRUG
OTHER
No Results Yet
39
Participants
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-05
Completion:
2026-12-31
Conditions
Wound Healing and Prevention
Oral Inflammation
Photobiomodulation
Post-operative Pain Management
Tooth Extraction Site Healing
Interventions
OTHER
No Results Yet
208
Participants
A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-06
Completion:
2027-01-12
Conditions
Respiratory Syncytial Virus Infections
Interventions
BIOLOGICAL
No Results Yet
100
Participants
Real-world Outcomes Among Patients With Melanoma Treated With Neoadjuvant Nivolumab+Relatlimab or Nivolumab+Ipilimumab
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-11
Completion:
2025-11-06
Conditions
Melanoma
Interventions
BIOLOGICAL
No Results Yet
90
Participants
A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-18
Completion:
2028-05-31
Conditions
Autoimmune Haemolytic Anaemia
Interventions
DRUG
No Results Yet
54
Participants
A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-10
Completion:
2028-02-01
Conditions
Neuroblastoma Recurrent
Interventions
DRUG
No Results Yet
184
Participants
CSIMEMPHIS: Long-term Follow-up of Medulloblastoma Survivors That Received Craniospinal Irradiation
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-31
Completion:
2030-10-31
Conditions
Medulloblastoma
No Results Yet
30
Participants
Multimedia Aid for Genetic Testing in Gynecologic Oncology
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-10-10
Completion:
2026-10-30
Conditions
Ovary Cancer
Endometrial Cancer
Interventions
BEHAVIORAL
No Results Yet
768
Participants
Shortening Adjuvant Photon and Proton Irradiation (SAPPHIRe-II): A 4 Cohort, Randomized, Phase II Multi-center Trial Evaluating Shorter Schedules of Adjuvant Regional Nodal Irradiation Among Women and Men With Node-positive and High-risk Node-negative Invasive Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-19
Completion:
2029-01-01
Conditions
Breast Cancer
Interventions
RADIATION
No Results Yet
52
Participants
Evaluating NALIRIFOX vs Modified Gemcitabine, Nab-Paclitaxel and Cisplatin in Patients With Locally Advanced and Metastatic Pancreatic Adenocarcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-07
Completion:
2028-05-31
Conditions
Metastatic Pancreatic Adenocarcinoma
Locally Advanced Pancreatic Adenocarcinoma
Interventions
DRUG
No Results Yet
4580
Participants
A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-10
Completion:
2027-10-18
Conditions
Human Immunodeficiency Virus (HIV)
HIV Pre-Exposure Prophylaxis
Interventions
DRUG
No Results Yet
120
Participants
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-28
Completion:
2034-07-31
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
360
Participants
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-06-19
Completion:
2027-03-31
Conditions
Major Depressive Disorder (MDD)
Major Depressive Disorder With Anxious Distress
Interventions
DRUG
No Results Yet
11800
Participants
A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-22
Completion:
2029-12-14
Conditions
Diabetes Mellitus, Type 2
Hypertension
Cardiovascular Diseases
Interventions
DRUG
No Results Yet
590
Participants
A Study to Compare the Combination of BMS-986504 With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-28
Completion:
2031-08-12
Conditions
Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Interventions
DRUG
OTHER
No Results Yet
17
Participants
Mobile Health Program for Teens With Congenital Heart Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-17
Completion:
2025-11-02
Conditions
Congenital Heart Disease in Adolescence
Health Behavior
Interventions
BEHAVIORAL
No Results Yet
336
Participants
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-05
Completion:
2030-12-31
Conditions
Locally Advanced Cervical Adenocarcinoma
Locally Advanced Cervical Adenosquamous Carcinoma
Locally Advanced Cervical Squamous Cell Carcinoma
Stage IIIA Cervical Cancer FIGO 2018
Stage IIIB Cervical Cancer FIGO 2018
Stage IIIC1 Cervical Cancer FIGO 2018
Stage IIIC2 Cervical Cancer FIGO 2018
Stage IVA Cervical Cancer FIGO 2018
Interventions
PROCEDURE
RADIATION
DRUG
BIOLOGICAL
No Results Yet
111
Participants
Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2026-06-01
Completion:
2027-07-31
Conditions
Muscle Invasive Bladder Urothelial Carcinoma
Stage II Bladder Cancer AJCC v8
Stage IIIA Bladder Cancer AJCC v8
Interventions
PROCEDURE
BIOLOGICAL
RADIATION
OTHER
No Results Yet
125
Participants
Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-09
Completion:
2026-06-30
Conditions
Kidney Disease
Peritoneal Dialysis (PD)
End Stage Kidney Disease (ESRD)
Interventions
DEVICE
No Results Yet
153
Participants
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-21
Completion:
2033-12-04
Conditions
Heterozygous Familial Hypercholesterolemia (HeFH)
Interventions
DRUG
No Results Yet
60
Participants
A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-09
Completion:
2027-07-31
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
25
Participants
Microsurgery and Periodontal Healing
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-31
Completion:
2027-05-31
Conditions
Periodontal Diseases
Interventions
PROCEDURE
No Results Yet
32
Participants
The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-31
Completion:
2027-09-30
Conditions
Dental Implantation
Missing Teeth
Periodontitis, Adult
Mucositis
Interventions
DEVICE
No Results Yet
24
Participants
Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-05
Completion:
2026-09-30
Conditions
Pain, Acute
Interventions
DRUG
No Results Yet
10
Participants
Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-29
Completion:
2030-08-31
Conditions
Arrhythmogenic Cardiomyopathy
PKP2-ACM
PKP2-ARVC
No Results Yet
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