Clinical Trials
Showing trials with last updates posted in 2025.
125
Participants
Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-09
Completion:
2026-06-30
Conditions
Kidney Disease
Peritoneal Dialysis (PD)
End Stage Kidney Disease (ESRD)
Interventions
DEVICE
No Results Yet
153
Participants
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-21
Completion:
2033-12-04
Conditions
Heterozygous Familial Hypercholesterolemia (HeFH)
Interventions
DRUG
No Results Yet
60
Participants
A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-09
Completion:
2027-07-31
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
25
Participants
Microsurgery and Periodontal Healing
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-31
Completion:
2027-05-31
Conditions
Periodontal Diseases
Interventions
PROCEDURE
No Results Yet
32
Participants
The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-31
Completion:
2027-09-30
Conditions
Dental Implantation
Missing Teeth
Periodontitis, Adult
Mucositis
Interventions
DEVICE
No Results Yet
24
Participants
Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-05
Completion:
2026-09-30
Conditions
Pain, Acute
Interventions
DRUG
No Results Yet
10
Participants
Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-29
Completion:
2030-08-31
Conditions
Arrhythmogenic Cardiomyopathy
PKP2-ACM
PKP2-ARVC
No Results Yet
50
Participants
SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2028-01-01
Conditions
Soft Tissue Sarcoma
Interventions
DRUG
No Results Yet
80
Participants
CAR T-cell Long-Term Follow-Up, Quality of Life and Adverse Reactions
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-10-24
Completion:
2028-07-31
Conditions
B-Cell Acute Lymphoblastic Leukemia (B-ALL)
No Results Yet
300
Participants
Study of Lenacapavir as a Once-Yearly Injection for HIV Pre-exposure Prophylaxis (PrEP)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-22
Completion:
2028-09-30
Conditions
HIV Pre-exposure Prophylaxis
Interventions
DRUG
No Results Yet
4390
Participants
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-31
Completion:
2027-07-22
Conditions
Human Immunodeficiency Virus (HIV)
HIV Pre-Exposure Prophylaxis
Interventions
DRUG
No Results Yet
0
Participants
Measuring Acute Drug Demand in Humans II
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-15
Completion:
2027-12-01
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
351
Participants
A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-27
Completion:
2027-10-30
Conditions
Metastatic Gastric Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Interventions
DRUG
No Results Yet
144
Participants
Implementation of a Beauty Salon-Based Strategy for Blood Pressure Management Among Women
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2028-05-31
Conditions
Hypertension
Interventions
BEHAVIORAL
No Results Yet
50
Participants
A Food Security Intervention for the Prevention of Cancer in Low-income Families
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2026-10-30
Conditions
Obesity-Related Malignant Neoplasm
Interventions
BEHAVIORAL
OTHER
No Results Yet
1000
Participants
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naรฏve.
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-28
Completion:
2028-09-12
Conditions
Metastatic Castration Sensitive Prostate Cancer (mCSPC)
Hormone Sensitive Prostate Cancer
Prostate Cancer
Cancer of the Prostate
Interventions
DRUG
No Results Yet
42
Participants
Phase I/II Clinical Trial of Universal Donor CD33 CAR Natural Killer Cells for AML
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2026-04-01
Completion:
2032-07-01
Conditions
Relapsed/Refractory AML
Interventions
BIOLOGICAL
No Results Yet
42
Participants
Biomarker-Guided Ruxolitinib for the Prevention of Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-09
Completion:
2028-04-05
Conditions
Hematopoietic and Lymphatic System Neoplasm
Interventions
OTHER
PROCEDURE
DRUG
No Results Yet
5
Participants
A Study of Efgartigimod in Patients With IgG4-Related Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-12
Completion:
2028-03-01
Conditions
IgG4-related Disease
Interventions
DRUG
No Results Yet
140
Participants
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-07
Completion:
2029-11-30
Conditions
Colorectal Cancer
Interventions
DRUG
No Results Yet
300
Participants
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-14
Completion:
2026-12-06
Conditions
COVID-19 Infection
Interventions
DRUG
No Results Yet
645
Participants
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-27
Completion:
2026-06-30
Conditions
Ulcerative Colitis
Inflammatory Bowel Diseases
Colitis
Colitis, Ulcerative
Interventions
DRUG
OTHER
No Results Yet
37
Participants
Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2027-06-14
Conditions
Locally Advanced Lung Non-Small Cell Carcinoma
Metastatic Lung Non-Small Cell Carcinoma
Stage III Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
Interventions
PROCEDURE
DRUG
BIOLOGICAL
No Results Yet
155
Participants
Development of an Educational Patient Decision Aid (Treatments in Advanced Cancer - Decision Aid, TA-DA) to Promote Shared Decision Making for Third-line or Beyond Palliative Systemic Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-10
Completion:
2028-07-31
Conditions
Advanced Cancer
Interventions
OTHER
No Results Yet
50
Participants
Interview of Patients With HR+/HER2- Metastatic Breast Cancer Who Received Capivasertib + Fulvestrant
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-31
Completion:
2025-12-31
Conditions
Metastatic Breast Cancer
Interventions
OTHER
No Results Yet
694
Participants
A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-03
Completion:
2031-12-31
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
400
Participants
Breaking Fasts Ahead of Cardiac Caths
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-10-13
Completion:
2026-06-30
Conditions
Stable Angina (SA)
Unstable Angina (UA)
NSTEMI - Non-ST Segment Elevation MI
Interventions
BEHAVIORAL
No Results Yet
15
Participants
Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-31
Completion:
2027-07-31
Conditions
Pancreatic Insufficiency
Cystic Fibrosis-related Diabetes
Interventions
DRUG
No Results Yet
150
Participants
An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-07
Completion:
2032-04-19
Conditions
Metastatic Hormone-sensitive Prostate Cancer
Interventions
DRUG
No Results Yet
982
Participants
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-10-03
Completion:
2028-01-30
Conditions
Cachexia
Metastatic Pancreatic Ductal Adenocarcinoma
Interventions
DRUG
No Results Yet
40
Participants
A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2026-02-15
Completion:
2027-08-29
Conditions
HIV-1-infection
Interventions
BIOLOGICAL
No Results Yet
366
Participants
A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-15
Completion:
2029-10-12
Conditions
Plaque Psoriasis
Interventions
DRUG
OTHER
No Results Yet
40
Participants
Alpha-Stim AIDยฎ Together With Life Coaching for the Support of Burnout Symptoms in Healthcare Workers
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2026-12-15
Conditions
Psychiatric Disorder
Interventions
PROCEDURE
OTHER
BEHAVIORAL
No Results Yet
100
Participants
Study of IgPro20 to Prevent Infection in People With Multiple Myeloma and Hypogammaglobulinemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-08
Completion:
2029-05-08
Conditions
Multiple Myeloma
Hypogammaglobulinemia
Hypogammaglobulinemia, Acquired
Interventions
DRUG
No Results Yet
586
Participants
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-14
Completion:
2028-09-11
Conditions
Alzheimer's Disease
Interventions
DRUG
OTHER
No Results Yet
586
Participants
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-21
Completion:
2028-09-11
Conditions
Alzheimer's Disease
Interventions
DRUG
OTHER
No Results Yet
365
Participants
Aerodynamic Measurements in the Pediatric Population
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-31
Completion:
2030-12-31
Conditions
Normal Voice
Interventions
DEVICE
No Results Yet
294
Participants
JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-29
Completion:
2027-11-30
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
68
Participants
Piloting a Patient Navigator Program for Weight Loss
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-15
Completion:
2027-02-15
Conditions
Obesity
Overweight
Interventions
BEHAVIORAL
No Results Yet
436
Participants
A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-21
Completion:
2027-09-30
Conditions
Severe Asthma
Interventions
DRUG
No Results Yet
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