Clinical Trials
Showing trials with last updates posted in 2025.
5
Participants
A Study of Efgartigimod in Patients With IgG4-Related Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-12
Completion:
2028-03-01
Conditions
IgG4-related Disease
Interventions
DRUG
No Results Yet
140
Participants
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-07
Completion:
2029-11-30
Conditions
Colorectal Cancer
Interventions
DRUG
No Results Yet
300
Participants
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-14
Completion:
2026-12-06
Conditions
COVID-19 Infection
Interventions
DRUG
No Results Yet
645
Participants
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-27
Completion:
2026-06-30
Conditions
Ulcerative Colitis
Inflammatory Bowel Diseases
Colitis
Colitis, Ulcerative
Interventions
DRUG
OTHER
No Results Yet
20
Participants
Study of Deucravacitinib for Refractory Adults With Dermatomyositis/Juvenile Dermatomyositis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-17
Completion:
2028-03-30
Conditions
Myositis
Dermatomyositis
Interventions
DRUG
No Results Yet
37
Participants
Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2027-06-14
Conditions
Locally Advanced Lung Non-Small Cell Carcinoma
Metastatic Lung Non-Small Cell Carcinoma
Stage III Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
Interventions
PROCEDURE
DRUG
BIOLOGICAL
No Results Yet
155
Participants
Development of an Educational Patient Decision Aid (Treatments in Advanced Cancer - Decision Aid, TA-DA) to Promote Shared Decision Making for Third-line or Beyond Palliative Systemic Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-10
Completion:
2028-07-31
Conditions
Advanced Cancer
Interventions
OTHER
No Results Yet
50
Participants
Interview of Patients With HR+/HER2- Metastatic Breast Cancer Who Received Capivasertib + Fulvestrant
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-31
Completion:
2025-12-31
Conditions
Metastatic Breast Cancer
Interventions
OTHER
No Results Yet
1000
Participants
Clinical Genetics Branch Eligibility Screening Survey
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-17
Completion:
2035-01-01
Conditions
Melanoma
Li-Fraumeni Syndrome
Pulmonary Blastoma
Chordoma
Congenital Bone Marrow Failure Syndromes
Costello Syndrome
Fanconi Anemia
CFC Syndrome (CFCS)
Legius Syndrome
RASopathies
No Results Yet
694
Participants
A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-03
Completion:
2031-12-31
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
23
Participants
Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-17
Completion:
2028-08-18
Conditions
Muscle Weakness
Problems Moving Their Arms and Legs
Interventions
DEVICE
No Results Yet
400
Participants
Breaking Fasts Ahead of Cardiac Caths
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-10-13
Completion:
2026-06-30
Conditions
Stable Angina (SA)
Unstable Angina (UA)
NSTEMI - Non-ST Segment Elevation MI
Interventions
BEHAVIORAL
No Results Yet
30
Participants
Development of an Interview-Informed Timeline Follow-Back (TLFB) for Opioid Use in the Era of Fentanyl
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-17
Completion:
2027-05-31
Conditions
Substance Use Disorders (SUDs)
No Results Yet
15
Participants
Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-31
Completion:
2027-07-31
Conditions
Pancreatic Insufficiency
Cystic Fibrosis-related Diabetes
Interventions
DRUG
No Results Yet
180
Participants
Tibulizumab Skin Healing and Inflammation Evaluation for Lasting Defense
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-16
Completion:
2026-09-30
Conditions
Hidradenitis Suppurativa (HS)
Interventions
BIOLOGICAL
OTHER
No Results Yet
50
Participants
A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-17
Completion:
2026-08-31
Conditions
Cardiometabolic Risk Factors
Mental Health
No Results Yet
18
Participants
177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-17
Completion:
2032-07-01
Conditions
Thyroid Cancer
Interventions
DIAGNOSTIC_TEST
OTHER
DRUG
No Results Yet
150
Participants
An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-07
Completion:
2032-04-19
Conditions
Metastatic Hormone-sensitive Prostate Cancer
Interventions
DRUG
No Results Yet
982
Participants
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-10-03
Completion:
2028-01-30
Conditions
Cachexia
Metastatic Pancreatic Ductal Adenocarcinoma
Interventions
DRUG
No Results Yet
40
Participants
A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2026-02-15
Completion:
2027-08-29
Conditions
HIV-1-infection
Interventions
BIOLOGICAL
No Results Yet
366
Participants
A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-15
Completion:
2029-10-12
Conditions
Plaque Psoriasis
Interventions
DRUG
OTHER
No Results Yet
40
Participants
Alpha-Stim AIDยฎ Together With Life Coaching for the Support of Burnout Symptoms in Healthcare Workers
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2026-12-15
Conditions
Psychiatric Disorder
Interventions
PROCEDURE
OTHER
BEHAVIORAL
No Results Yet
100
Participants
Study of IgPro20 to Prevent Infection in People With Multiple Myeloma and Hypogammaglobulinemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-08
Completion:
2029-05-08
Conditions
Multiple Myeloma
Hypogammaglobulinemia
Hypogammaglobulinemia, Acquired
Interventions
DRUG
No Results Yet
586
Participants
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-14
Completion:
2028-09-11
Conditions
Alzheimer's Disease
Interventions
DRUG
OTHER
No Results Yet
586
Participants
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-21
Completion:
2028-09-11
Conditions
Alzheimer's Disease
Interventions
DRUG
OTHER
No Results Yet
365
Participants
Aerodynamic Measurements in the Pediatric Population
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-31
Completion:
2030-12-31
Conditions
Normal Voice
Interventions
DEVICE
No Results Yet
294
Participants
JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-29
Completion:
2027-11-30
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
68
Participants
Piloting a Patient Navigator Program for Weight Loss
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-15
Completion:
2027-02-15
Conditions
Obesity
Overweight
Interventions
BEHAVIORAL
No Results Yet
436
Participants
A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-21
Completion:
2027-09-30
Conditions
Severe Asthma
Interventions
DRUG
No Results Yet
285
Participants
A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-05
Completion:
2026-08-21
Conditions
Obesity
Overweight
Overweight With One Weight Related Comorbidity
Interventions
DRUG
No Results Yet
347
Participants
A Study of Mezagitamab in Adults With Primary IgA Nephropathy Kidney Condition
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-15
Completion:
2028-09-07
Conditions
Kidney Disease
Interventions
DRUG
No Results Yet
36
Participants
Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2029-05-31
Conditions
Melanoma
Interventions
DRUG
No Results Yet
160
Participants
A Clinical Study of V940 and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-29
Completion:
2028-07-22
Conditions
Malignant Melanoma
Interventions
BIOLOGICAL
OTHER
No Results Yet
140
Participants
Biventricular Remodeling in Transcatheter Tricuspid Valve Replacement - Acute Hemodynamic Instability Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2026-01-31
Completion:
2026-05-01
Conditions
Tricuspid Regurgitation
Heart Failure
Structural Heart Disease
Interventional Cardiology
No Results Yet
300
Participants
Deciphering the Genetic Architecture of Autoimmune Diseases
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-17
Completion:
2030-04-22
Conditions
Autoimmune Diseases
No Results Yet
30
Participants
Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-17
Completion:
2028-07-14
Conditions
Lung Transplantation
Interventions
DRUG
No Results Yet
50
Participants
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-26
Completion:
2030-12-30
Conditions
Malignant Neoplasm
Interventions
BIOLOGICAL
No Results Yet
30
Participants
VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commercial Off-The-Shelf (COTS) Catheters
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-17
Completion:
2026-12-01
Conditions
Ventricular Arrhythmia
Interventions
DEVICE
No Results Yet
73
Participants
Zelenectide Pevedotin in NECTIN4 Amplified Advanced or Metastatic Non-small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-18
Completion:
2028-08-31
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
10
Participants
Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-15
Completion:
2026-10-30
Conditions
Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
Showing 40 trials per page ยท Total 107627 trials