Clinical Trials
Showing trials with last updates posted in 2025.
285
Participants
A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-05
Completion:
2026-08-21
Conditions
Obesity
Overweight
Overweight With One Weight Related Comorbidity
Interventions
DRUG
No Results Yet
347
Participants
A Study of Mezagitamab in Adults With Primary IgA Nephropathy Kidney Condition
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-15
Completion:
2028-09-07
Conditions
Kidney Disease
Interventions
DRUG
No Results Yet
36
Participants
Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2029-05-31
Conditions
Melanoma
Interventions
DRUG
No Results Yet
140
Participants
Biventricular Remodeling in Transcatheter Tricuspid Valve Replacement - Acute Hemodynamic Instability Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2026-01-31
Completion:
2026-05-01
Conditions
Tricuspid Regurgitation
Heart Failure
Structural Heart Disease
Interventional Cardiology
No Results Yet
50
Participants
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-26
Completion:
2030-12-30
Conditions
Malignant Neoplasm
Interventions
BIOLOGICAL
No Results Yet
73
Participants
Zelenectide Pevedotin in NECTIN4 Amplified Advanced or Metastatic Non-small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-18
Completion:
2028-08-31
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
10
Participants
Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-15
Completion:
2026-10-30
Conditions
Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
24
Participants
Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-31
Completion:
2027-05-31
Conditions
Ovarian Cancer
Interventions
DRUG
No Results Yet
450
Participants
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-18
Completion:
2028-06-13
Conditions
Bipolar Disorder Type I With Mania
Interventions
DRUG
No Results Yet
416
Participants
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-18
Completion:
2027-01-08
Conditions
Chronic Kidney Disease
Interventions
DRUG
No Results Yet
122
Participants
A First-in-Human Study Using BDC-4182 as a Single Agent in Advanced Gastric and Gastroesophageal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-26
Completion:
2027-05-31
Conditions
Gastric Cancer Adenocarcinoma Metastatic
Gastroesophageal Adenocarcinoma
Interventions
DRUG
No Results Yet
17
Participants
Comparison of Urinary Flow Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-06
Completion:
2026-12-31
Conditions
Urinary Retention
Interventions
DEVICE
No Results Yet
150
Participants
BID LTM Digital Intervention in Aging
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-20
Completion:
2027-12-31
Conditions
Long-Term Memory
Inhibitory Control
Interventions
BEHAVIORAL
No Results Yet
84
Participants
Visual Perception in Schizophrenia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-03
Completion:
2027-01-31
Conditions
Schizophrenia Disorders
Bipolar Disorder
Schizo Affective Disorder
Interventions
OTHER
No Results Yet
37
Participants
Effect of Phenytoin or Itraconazole on How BGB-16673 is Absorbed and Removed From the Body in Healthy Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-04-03
Completion:
2025-10-13
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
1170
Participants
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-10-28
Completion:
2027-04-01
Conditions
Chronic Kidney Disease(CKD)
Type 2 DM
Type 2 Diabetes Mellitus (T2DM)
Interventions
OTHER
No Results Yet
800
Participants
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-10-28
Completion:
2027-04-01
Conditions
Chronic Kidney Disease(CKD)
Type 2 DM
Type 2 Diabetes Mellitus (T2DM)
Interventions
OTHER
No Results Yet
48
Participants
Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2026-07-19
Completion:
2029-06-02
Conditions
Locally Advanced Adrenal Cortical Carcinoma
Metastatic Adrenal Cortical Carcinoma
Recurrent Adrenal Cortical Carcinoma
Stage III Adrenal Cortical Carcinoma AJCC v8
Stage IV Adrenal Cortical Carcinoma AJCC v8
Unresectable Adrenal Cortical Carcinoma
Interventions
PROCEDURE
DRUG
BIOLOGICAL
No Results Yet
420
Participants
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI Versus AAA617 in PSMA Positive First-line mCRPC
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-11
Completion:
2029-04-09
Conditions
Metastatic Castration Resistant Prostate Cancer (mCRPC)
Interventions
DRUG
No Results Yet
594
Participants
A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-02
Completion:
2027-08-31
Conditions
Advanced Lung Cancer
Interventions
BIOLOGICAL
No Results Yet
50
Participants
A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-09
Completion:
2026-01-31
Conditions
Phosphomannomutase 2 Deficiency
PMM2-CDG
Interventions
DRUG
No Results Yet
594
Participants
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-04-11
Completion:
2027-12-13
Conditions
Lymphoma, Large B-Cell, Diffuse
Interventions
BIOLOGICAL
DRUG
No Results Yet
100
Participants
A Single-Arm Study Evaluating the Effectiveness and Safety of Suzetrigine (SUZ) for Acute Pain After Aesthetic or Reconstructive Surgeries
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-03-21
Completion:
2025-10-24
Conditions
Acute Pain
Interventions
DRUG
No Results Yet
135
Participants
A Placebo-Controlled Study Evaluating the Effects of Arrabina P on Satiety in Healthy Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-04-15
Completion:
2025-10-28
Conditions
Satiety
Appetite Regulation
Weight Control
Interventions
DIETARY_SUPPLEMENT
OTHER
No Results Yet
250
Participants
A Study to Evaluate the Efficacy and Safety of KarXT in Acutely Psychotic Japanese Adult Participants With Schizophrenia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-06-10
Completion:
2028-09-23
Conditions
Schizophrenia
Interventions
DRUG
OTHER
No Results Yet
420
Participants
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-06
Completion:
2027-12-01
Conditions
NSCLC (Non-small Cell Lung Cancer)
Non-Small Cell Lung Cancer
NSCLC
NSCLC (Non-small Cell Lung Carcinoma)
NSCLC (Advanced Non-small Cell Lung Cancer)
Interventions
DRUG
No Results Yet
530
Participants
A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-06-17
Completion:
2028-09-30
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
18
Participants
A Study to Test How Well BI 3000202 is Tolerated by People With Type 1 Interferonopathies
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-29
Completion:
2026-12-06
Conditions
Type 1 Interferonopathies
Interventions
DRUG
No Results Yet
150
Participants
A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-06-04
Completion:
2027-03-31
Conditions
Dravet Syndrome
Interventions
DRUG
OTHER
No Results Yet
100
Participants
New York Better Breathing Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-15
Completion:
2028-03-15
Conditions
Localized Lung Carcinoma
Stage I Lung Cancer AJCC v8
Stage II Lung Cancer AJCC v8
Stage III Lung Cancer AJCC v8
Interventions
PROCEDURE
OTHER
No Results Yet
550
Participants
A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-04-16
Completion:
2028-02-24
Conditions
RSV Infection
Interventions
BIOLOGICAL
No Results Yet
160
Participants
A Study of Raludotatug Deruxtecan (R-DXd) in People With Gastrointestinal Cancers (MK-5909-005)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-04-01
Completion:
2026-07-06
Conditions
Gastrointestinal Cancer
Interventions
BIOLOGICAL
No Results Yet
360
Participants
A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-03
Completion:
2030-02-18
Conditions
Castration-Resistant Prostatic Cancer
Metastasis
Interventions
DRUG
No Results Yet
120
Participants
WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-10
Completion:
2027-12-31
Conditions
Diabetes
Weight Loss
Interventions
BEHAVIORAL
PROCEDURE
No Results Yet
75
Participants
Study of Adaptive Immunotherapy With VEGFR-TKI in Patients With Advanced RCC
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-02-25
Completion:
2028-02-29
Conditions
Renal Cell Carcinoma
Clear Cell Renal Cell Carcinoma
Interventions
DRUG
No Results Yet
605
Participants
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-01
Completion:
2028-02-29
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
250
Participants
A Study of BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-04-10
Completion:
2028-05-15
Conditions
CLL
Chronic Lymphocytic Leukemia
Interventions
DRUG
No Results Yet
315
Participants
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-04-29
Completion:
2026-11-30
Conditions
Generalized Anxiety Disorder (GAD)
Interventions
DRUG
No Results Yet
144
Participants
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-03-03
Completion:
2027-08-31
Conditions
Obese or Overweight Healthy Volunteers
Type 2 Diabetes Mellitus (T2DM)
Interventions
DRUG
No Results Yet
54
Participants
A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-02-19
Completion:
2028-08-19
Conditions
Well Differentiated Liposarcoma
Dedifferentiated Liposarcoma
Liposarcoma
Myxoid Liposarcoma
Round Cell Liposarcoma
Myxoid Pleomorphic Liposarcoma
Pleomorphic Liposarcoma
Unresectable Liposarcoma
Unresectable Dedifferentiated Liposarcoma
Interventions
DRUG
No Results Yet
Showing 40 trials per page ยท Total 107726 trials