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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06685835 | ACTIVE_NOT_RECRUITING | PHASE2
214 Participants

A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-16
Completion: 2026-05-22
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
NCT06685757 | RECRUITING | PHASE3
120 Participants

A Trial of Felzartamab in Kidney Transplant Recipients With Late Antibody-Mediated Rejection (AMR)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-03
Completion: 2026-12-01
Conditions
Antibody-mediated Rejection
Interventions
DRUG
No Results Yet
NCT06685718 | RECRUITING | PHASE1
93 Participants

A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-26
Completion: 2028-04-30
Conditions
Non-Small Cell Lung Cancer Lung Cancer NSCLC NSCLC (Non-small Cell Lung Carcinoma) EGFR Activating Mutation EGFR Mutation-Related Tumors
Interventions
DRUG
No Results Yet
NCT06682988 | RECRUITING | PHASE2
110 Participants

A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-28
Completion: 2028-03-31
Conditions
Advanced High-Grade Epithelial Ovarian Primary Peritoneal Fallopian Tube Cancers High Folate Receptor-Alpha Expression Platinum Resistant
Interventions
DRUG
No Results Yet
NCT06680830 | RECRUITING | PHASE2
150 Participants

A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-01-17
Completion: 2026-09-30
Conditions
Parkinson Disease Parkinson Idiopathic Parkinson Disease Early Parkinson Disease (Early PD) Parkinson Disease, Idiopathic
Interventions
DRUG OTHER
No Results Yet
NCT06680479 | RECRUITING | PHASE1
30 Participants

Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-01
Completion: 2027-04-30
Conditions
HIV-1
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06679140 | RECRUITING | PHASE3
2330 Participants

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-08
Completion: 2026-12-06
Conditions
COVID-19 SARS-CoV-2 Infection
Interventions
DRUG
No Results Yet
NCT06670638 | RECRUITING
50 Participants

Development of a Novel Endoscopic Index and Patient-reported Outcome Measure for Clinical Trials in Participants With Permanent Ileostomy

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-19
Completion: 2026-06-30
Conditions
Crohns Disease
No Results Yet
NCT06667700 | RECRUITING | PHASE3
3082 Participants

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-02
Completion: 2031-01-26
Conditions
Coronavirus Disease (COVID-19)
Interventions
DRUG
No Results Yet
NCT06662500 | RECRUITING | NA
158 Participants

FORWARD CAD IDE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-04
Completion: 2026-08-31
Conditions
Coronary Arterial Disease (CAD)
Interventions
DEVICE
No Results Yet
NCT06659640 | RECRUITING | PHASE1/PHASE2
120 Participants

A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-11
Completion: 2028-01-05
Conditions
Hereditary Hemorrhagic Telangiectasia
Interventions
DRUG
No Results Yet
NCT06655844 | RECRUITING | NA
30 Participants

Sana Device for Post-Treatment Lyme Disease Syndrome Chronic Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-04
Completion: 2026-03-31
Conditions
Post-treatment Lyme Disease Syndrome Chronic Pain
Interventions
DEVICE
No Results Yet
NCT06654843 | RECRUITING | NA
630 Participants

Free Time For Wellness 2+

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-15
Completion: 2026-09-30
Conditions
Physical Inactivity
Interventions
BEHAVIORAL
No Results Yet
NCT06651632 | RECRUITING | NA
280 Participants

WATER IV Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-02-03
Completion: 2027-07-31
Conditions
Localized Prostate Cancer
Interventions
DEVICE PROCEDURE
No Results Yet
NCT06647498 | RECRUITING | PHASE2/PHASE3
280 Participants

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-22
Completion: 2034-03-31
Conditions
Alzheimers Disease Dementia Alzheimers Disease, Familial
Interventions
DRUG
No Results Yet
NCT06645145 | COMPLETED | NA
170 Participants

Language Learning and Language Experience

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-31
Completion: 2025-08-30
Conditions
Typically Developing Children Ages 3 to 6
Interventions
BEHAVIORAL
No Results Yet
NCT06644664 | RECRUITING | NA
300 Participants

Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-24
Completion: 2026-08-31
Conditions
Tobacco-Related Carcinoma
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06643481 | ACTIVE_NOT_RECRUITING | PHASE2
251 Participants

A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-17
Completion: 2026-09-21
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06641466 | RECRUITING | PHASE3
723 Participants

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-03-11
Completion: 2026-11-29
Conditions
Menstrual Migraine
Interventions
DRUG
No Results Yet
NCT06638554 | RECRUITING | NA
6000 Participants

Integrating Telehealth to Advance Lung Cancer Screening

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-07-09
Completion: 2027-01-31
Conditions
Early Detection of Cancer Telemedicine Decision Making
Interventions
BEHAVIORAL
No Results Yet
NCT06637501 | ACTIVE_NOT_RECRUITING | PHASE2
94 Participants

A Study to Investigate Sonrotoclax Combined With Zanubrutinib Versus Zanubrutinib Alone in Participants With Previously Untreated Chronic Lymphocytic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-14
Completion: 2027-10-31
Conditions
Chronic Lymphocytic Leukemia
Interventions
DRUG
No Results Yet
NCT06636383 | RECRUITING
140 Participants

Glycogen Storage Disease Type Ia (GSDIa) Disease Monitoring Program

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-04
Completion: 2036-12-31
Conditions
Glycogen Storage Disease Type Ia
Interventions
OTHER
No Results Yet
NCT06625593 | RECRUITING | PHASE1
168 Participants

A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-09
Completion: 2026-12-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06619756 | COMPLETED | NA
2 Participants

Anomia Treatment Predictors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-18
Completion: 2025-10-01
Conditions
Anomia (Word-Finding Impairment) Aphasia
Interventions
BEHAVIORAL
No Results Yet
NCT06616272 | RECRUITING | NA
40 Participants

Cervical Spine Focused Treatment for Patients With Persistent Concussion Symptoms and Neck Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-28
Completion: 2025-12-15
Conditions
Brain Concussion Neck Pain
Interventions
OTHER
No Results Yet
NCT06615752 | RECRUITING | PHASE1/PHASE2
99 Participants

Green Tea and Quercetin in Combination With Docetaxel Chemotherapy in Castration-resistant Prostate Cancer Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-03-31
Completion: 2028-04-30
Conditions
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Interventions
DRUG
No Results Yet
NCT06615479 | RECRUITING | PHASE3
440 Participants

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-03-12
Completion: 2027-12-30
Conditions
Relapsed or Refractory Multiple Myeloma (RRMM)
Interventions
DRUG
No Results Yet
NCT06613100 | RECRUITING | PHASE1
40 Participants

Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-25
Completion: 2027-01-22
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06610617 | COMPLETED | NA
48 Participants

Neuromodulation of Central Sensory Integration to Improve Postural Control

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-14
Completion: 2025-06-17
Conditions
Survivorship Quality of Life Cognitive Deficits, Mild
Interventions
DEVICE
No Results Yet
NCT06606028 | RECRUITING
200 Participants

Tumor-Informed ctDNA Testing of Head & Neck Intent Treatment of Squamous Cell Carcinoma

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-09
Completion: 2028-12-30
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
PROCEDURE OTHER
No Results Yet
NCT06605196 | NOT_YET_RECRUITING | NA
364 Participants

Improving Cancer Prevention and Control Through Academic-local Public Health Department Partnerships

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2027-12-31
Conditions
Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06601699 | RECRUITING | NA
48 Participants

Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 2

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-27
Completion: 2027-07-31
Conditions
Healthy
Interventions
DEVICE
No Results Yet
NCT06601686 | RECRUITING | NA
12 Participants

Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 1

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-01-08
Completion: 2026-10-31
Conditions
Healthy
Interventions
DEVICE
No Results Yet
NCT06601296 | RECRUITING | PHASE2
15 Participants

Radiotherapy in Combination With Checkpoint Inhibition for Patients With Metastatic Kidney Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-01
Completion: 2027-10-31
Conditions
Metastatic Renal Cell Carcinoma ( mRCC) OligoProgressive Metastatic Disease
Interventions
DRUG
No Results Yet
NCT06600906 | RECRUITING
70 Participants

Hyperpolarized 13C MRI to Predict Response in Pancreatic Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-01
Completion: 2030-08-01
Conditions
Pancreatic Ductal Adenocarcinoma Metastatic Pancreatic Ductal Adenocarcinoma Locally Advanced Pancreatic Ductal Adenocarcinoma
Interventions
DRUG PROCEDURE
No Results Yet
NCT06596473 | RECRUITING | PHASE1
21 Participants

A Study of BG-C477 in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-03
Completion: 2028-10-27
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06594705 | RECRUITING | NA
50 Participants

The JenaValve ALIGN-AR LVAD Registry

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-09
Completion: 2026-08-31
Conditions
Aortic Regurgitation Aortic Valve Insufficiency Aortic Insufficiency Aortic Valve Disease Left Ventricular Dysfunction
Interventions
DEVICE
No Results Yet
NCT06589596 | RECRUITING | PHASE1
237 Participants

An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-11
Completion: 2027-06-30
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06580080 | RECRUITING | NA
1850 Participants

Evaluation of Are You Ready?

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-15
Completion: 2028-03-31
Conditions
Teen Pregnancy Prevention
Interventions
BEHAVIORAL
No Results Yet
NCT06578247 | RECRUITING | PHASE3
700 Participants

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-19
Completion: 2030-06-26
Conditions
Leukemia
Interventions
DRUG
No Results Yet
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