Clinical Trials

Showing trials with last updates posted in 2025.

NCT06577441 | RECRUITING | PHASE2
54 Participants

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-06-12
Completion: 2027-03-01
Conditions
Myelodysplastic Syndrome
Interventions
PROCEDURE DRUG
No Results Yet
NCT06575660 | COMPLETED | NA
22 Participants

Digital Support for Mental Health Intervention in Patients With Inflammatory Bowel Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-23
Completion: 2025-10-09
Conditions
Inflammatory Bowel Diseases Anxiety Depression Ulcerative Colitis Crohn Disease
Interventions
BEHAVIORAL
No Results Yet
NCT06571110 | RECRUITING | NA
45 Participants

Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-03-15
Completion: 2026-04-01
Conditions
Fibromyalgia
Interventions
PROCEDURE
No Results Yet
NCT06570798 | RECRUITING | PHASE2
98 Participants

A Phase 2a Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-16
Completion: 2028-09-15
Conditions
Systemic Lupus Erythematosus Active Refractory Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
NCT06568549 | RECRUITING | PHASE4
350 Participants

Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf®/TRAC Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-06-13
Completion: 2030-12-31
Conditions
Kidney Transplantation Mycophenolate Mofetil
Interventions
DRUG
No Results Yet
NCT06566417 | COMPLETED
400 Participants

Social Media as a Risk Tool for HIV Prevention Needs

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-01
Completion: 2025-05-15
Conditions
HIV Prevention HIV Preexposure Prophylaxis
No Results Yet
NCT06565416 | RECRUITING | NA
225 Participants

Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-06-01
Completion: 2026-07-31
Conditions
Opioid Use Disorder Opioid Misuse Chronic Pain
Interventions
BEHAVIORAL
No Results Yet
NCT06559306 | RECRUITING | PHASE3
752 Participants

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-07-25
Completion: 2026-12-30
Conditions
Depressive Disorder, Major
Interventions
DRUG
No Results Yet
NCT06557265 | RECRUITING | PHASE1/PHASE2
96 Participants

A Phase 1/2 Study of NKX019, a CD19 Chimeric Antigen Receptor Natural Killer (CAR NK) Cell Therapy, in Subjects With Autoimmune Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-13
Completion: 2027-04-30
Conditions
Lupus Nephritis Primary Membranous Nephropathy
Interventions
DRUG
No Results Yet
NCT06553027 | RECRUITING | PHASE3
330 Participants

To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-20
Completion: 2026-03-31
Conditions
Parkinson Disease
Interventions
DRUG
No Results Yet
NCT06539754 | COMPLETED | NA
61 Participants

Patient Satisfaction During Cesarean Delivery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-25
Completion: 2025-11-10
Conditions
Patient Satisfaction
Interventions
BEHAVIORAL
No Results Yet
NCT06537310 | ACTIVE_NOT_RECRUITING | PHASE1
34 Participants

A Dose-escalation Study of RO7567132 as Single Agent and in Combination With Atezolizumab in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-16
Completion: 2029-06-19
Conditions
Cancer-Neoplasms
Interventions
DRUG
No Results Yet
NCT06536374 | NOT_YET_RECRUITING | PHASE2
50 Participants

Folate Study in Men With Advanced Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-06-30
Completion: 2027-12-31
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06535399 | RECRUITING | PHASE1
30 Participants

Study to Assess Drug Levels and Safety of Golcadomide (BMS-986369) in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-15
Completion: 2025-11-12
Conditions
Hepatic Impairment Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06534892 | RECRUITING | PHASE3
10356 Participants

An Extension and Crossover Vaccination Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus Given to Adults 60 Years of Age and Above Who Participated in RSV OA=ADJ-006 Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-01
Completion: 2026-09-30
Conditions
Respiratory Syncytial Virus Infections
Interventions
BIOLOGICAL
No Results Yet
NCT06531499 | RECRUITING | PHASE1
106 Participants

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-11
Completion: 2028-11-24
Conditions
Metastatic Castration-Resistant Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06521567 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
83 Participants

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-03-06
Completion: 2026-10-13
Conditions
Melanoma Hodgkin Lymphoma High and Low Grade Glioma Glioblastoma Multiforme (GBM) Diffuse Intrinsic Pontine Glioma (DIPG) Ependymoma Osteosarcoma Hepatic Tumors Hepatoblastoma Hepatocellular Carcinoma (HCC) Fibrolamellar Carcinoma Rhabdomyosarcoma
Interventions
DRUG
No Results Yet
NCT06518616 | RECRUITING | PHASE2
192 Participants

Meditation to Reduce Firefighter Distress

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-03
Completion: 2026-08-31
Conditions
Psychological Distress
Interventions
BEHAVIORAL
No Results Yet
NCT06507709 | RECRUITING | NA
25 Participants

Closed Sinus Augmentation With a Calcium Phosphosilicate Putty

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-08
Completion: 2027-04-30
Conditions
Dental Implant Maxillary Sinus Floor Augmentation
Interventions
PROCEDURE
No Results Yet
NCT06503146 | RECRUITING | PHASE2
320 Participants

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-09
Completion: 2028-06-01
Conditions
Sarcoma Small Cell Lung Cancer or Extrapulmonary Neuroendocrine Cancer (EP-NEC) Mesothelioma Pheochromocytoma/Paraganglioma (PPGL) Pancreatic Ductal Adenocarcinoma Ovarian Cancer Hepatocellular Carcinoma Gastric Cancer Cholangiocarcinoma Bladder Cancer
Interventions
DRUG
No Results Yet
NCT06497556 | RECRUITING | PHASE3
320 Participants

A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-23
Completion: 2027-09-30
Conditions
Non-Small Cell Lung Cancer KRAS G12C Lung Cancer
Interventions
DRUG
No Results Yet
NCT06489522 | ACTIVE_NOT_RECRUITING | NA
9 Participants

Parenting Intervention for Mothers With Substance Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-01-17
Completion: 2026-03-31
Conditions
Substance Use Disorders Children of Mothers With Substance Use Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT06487351 | NOT_YET_RECRUITING | NA
70 Participants

Intervention to Reduce Implicit Bias in Pharmacies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2027-07-31
Completion: 2029-01-31
Conditions
Bias, Implicit HIV Pre-exposure Prophylaxis
Interventions
BEHAVIORAL
No Results Yet
NCT06482437 | COMPLETED | PHASE2
81 Participants

Safety and Efficacy of NMD670 in Adult Patients With Type 1 and Type 2 Charcot-Marie-Tooth Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-30
Completion: 2025-10-28
Conditions
Charcot-Marie-Tooth Disease
Interventions
DRUG
No Results Yet
NCT06471504 | RECRUITING | NA
100 Participants

Use of Eye Tracking to Aid in Autism Risk Detection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-01-08
Completion: 2026-04-30
Conditions
Autism
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06471322 | TERMINATED | NA
2 Participants

A Multi-Disciplinary Technology-Based Care for Diabetic Ketoacidosis in Patients With Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-15
Completion: 2025-11-01
Conditions
Diabetic Ketoacidosis
Interventions
DEVICE OTHER
No Results Yet
NCT06468228 | RECRUITING | PHASE3
1280 Participants

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-27
Completion: 2026-12-31
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
NCT06462235 | RECRUITING | PHASE2
48 Participants

A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-25
Completion: 2028-07-31
Conditions
Gram-negative Bacterial Infection
Interventions
DRUG
No Results Yet
NCT06446531 | RECRUITING | PHASE1
64 Participants

Prevention of Progression of Prediabetes, Obesity and CV Risk

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-11
Completion: 2027-07-31
Conditions
Pre-Diabetes Weight, Body Cardiovascular Diseases
Interventions
DRUG
No Results Yet
NCT06441604 | RECRUITING | PHASE2
30 Participants

Extended-release Buprenorphine as a Novel Low-dose Induction Strategy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-27
Completion: 2026-07-31
Conditions
Opioid Use Disorder
Interventions
DRUG
No Results Yet
NCT06434233 | RECRUITING | PHASE4
120 Participants

Opioid Use After Laparoscopic Salpingectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-04-25
Completion: 2026-11-30
Conditions
Opioid Use Post-operative Pain Sterility, Female
Interventions
DRUG
No Results Yet
NCT06434207 | RECRUITING
10 Participants

Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-31
Completion: 2025-12-31
Conditions
Congenital Heart Disease Single-ventricle Thrombosis
Interventions
OTHER
No Results Yet
NCT06430801 | RECRUITING | PHASE3
1200 Participants

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-05
Completion: 2028-10-30
Conditions
Crohn's Disease
Interventions
DRUG OTHER
No Results Yet
NCT06428396 | RECRUITING | PHASE2
120 Participants

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-27
Completion: 2027-05-05
Conditions
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT06422884 | RECRUITING | PHASE2
200 Participants

A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-15
Completion: 2026-10-31
Conditions
Idiopathic Pulmonary Fibrosis Progressive Fibrosing Interstitial Lung Disease
Interventions
DRUG
No Results Yet
NCT06422806 | RECRUITING | PHASE3
365 Participants

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-11
Completion: 2026-06-30
Conditions
Metastatic Dedifferentiated Liposarcoma Metastatic Undifferentiated Pleomorphic Sarcoma Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 Unresectable Dedifferentiated Liposarcoma Unresectable Undifferentiated Pleomorphic Sarcoma
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT06421636 | RECRUITING | PHASE2
95 Participants

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-30
Completion: 2028-01-24
Conditions
Non-Transfusion Dependent Beta-Thalassemia (NTDT)
Interventions
DRUG
No Results Yet
NCT06418711 | TERMINATED | PHASE3
132 Participants

ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-11
Completion: 2025-11-10
Conditions
MAC Lung Disease Treatment Refractory MAC Lung Disease Mycobacterium Infections, Nontuberculous
Interventions
DRUG
No Results Yet
NCT06417775 | RECRUITING | PHASE3
496 Participants

Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-10
Completion: 2027-06-30
Conditions
Migraine
Interventions
DRUG
No Results Yet
NCT06413498 | RECRUITING | PHASE3
450 Participants

A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-23
Completion: 2028-07-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
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