Clinical Trials

NCT06553027 | RECRUITING | PHASE3
330 Participants

To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-20
Completion: 2026-03-31
Conditions
Parkinson Disease
Interventions
DRUG
No Results Yet
NCT06539754 | COMPLETED | NA
61 Participants

Patient Satisfaction During Cesarean Delivery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-25
Completion: 2025-11-10
Conditions
Patient Satisfaction
Interventions
BEHAVIORAL
No Results Yet
NCT06537310 | ACTIVE_NOT_RECRUITING | PHASE1
34 Participants

A Dose-escalation Study of RO7567132 as Single Agent and in Combination With Atezolizumab in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-16
Completion: 2029-06-19
Conditions
Cancer-Neoplasms
Interventions
DRUG
No Results Yet
NCT06536374 | NOT_YET_RECRUITING | PHASE2
50 Participants

Folate Study in Men With Advanced Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-06-30
Completion: 2027-12-31
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06535399 | RECRUITING | PHASE1
30 Participants

Study to Assess Drug Levels and Safety of Golcadomide (BMS-986369) in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-15
Completion: 2025-11-12
Conditions
Hepatic Impairment Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06534892 | RECRUITING | PHASE3
10356 Participants

An Extension and Crossover Vaccination Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus Given to Adults 60 Years of Age and Above Who Participated in RSV OA=ADJ-006 Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-01
Completion: 2026-09-30
Conditions
Respiratory Syncytial Virus Infections
Interventions
BIOLOGICAL
No Results Yet
NCT06531499 | RECRUITING | PHASE1
106 Participants

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naรฏve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-11
Completion: 2028-11-24
Conditions
Metastatic Castration-Resistant Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06521567 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
83 Participants

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-03-06
Completion: 2026-10-13
Conditions
Melanoma Hodgkin Lymphoma High and Low Grade Glioma Glioblastoma Multiforme (GBM) Diffuse Intrinsic Pontine Glioma (DIPG) Ependymoma Osteosarcoma Hepatic Tumors Hepatoblastoma Hepatocellular Carcinoma (HCC) Fibrolamellar Carcinoma Rhabdomyosarcoma
Interventions
DRUG
No Results Yet
NCT06518616 | RECRUITING | PHASE2
192 Participants

Meditation to Reduce Firefighter Distress

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-03
Completion: 2026-08-31
Conditions
Psychological Distress
Interventions
BEHAVIORAL
No Results Yet
NCT06507709 | RECRUITING | NA
25 Participants

Closed Sinus Augmentation With a Calcium Phosphosilicate Putty

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-08
Completion: 2027-04-30
Conditions
Dental Implant Maxillary Sinus Floor Augmentation
Interventions
PROCEDURE
No Results Yet
NCT06503146 | RECRUITING | PHASE2
320 Participants

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-09
Completion: 2028-06-01
Conditions
Sarcoma Small Cell Lung Cancer or Extrapulmonary Neuroendocrine Cancer (EP-NEC) Mesothelioma Pheochromocytoma/Paraganglioma (PPGL) Pancreatic Ductal Adenocarcinoma Ovarian Cancer Hepatocellular Carcinoma Gastric Cancer Cholangiocarcinoma Bladder Cancer
Interventions
DRUG
No Results Yet
NCT06497556 | RECRUITING | PHASE3
320 Participants

A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-23
Completion: 2027-09-30
Conditions
Non-Small Cell Lung Cancer KRAS G12C Lung Cancer
Interventions
DRUG
No Results Yet
NCT06489522 | ACTIVE_NOT_RECRUITING | NA
9 Participants

Parenting Intervention for Mothers With Substance Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-01-17
Completion: 2026-03-31
Conditions
Substance Use Disorders Children of Mothers With Substance Use Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT06487351 | NOT_YET_RECRUITING | NA
70 Participants

Intervention to Reduce Implicit Bias in Pharmacies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2027-07-31
Completion: 2029-01-31
Conditions
Bias, Implicit HIV Pre-exposure Prophylaxis
Interventions
BEHAVIORAL
No Results Yet
NCT06482437 | COMPLETED | PHASE2
81 Participants

Safety and Efficacy of NMD670 in Adult Patients With Type 1 and Type 2 Charcot-Marie-Tooth Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-30
Completion: 2025-10-28
Conditions
Charcot-Marie-Tooth Disease
Interventions
DRUG
No Results Yet
NCT06471504 | RECRUITING | NA
100 Participants

Use of Eye Tracking to Aid in Autism Risk Detection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-01-08
Completion: 2026-04-30
Conditions
Autism
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06471322 | TERMINATED | NA
2 Participants

A Multi-Disciplinary Technology-Based Care for Diabetic Ketoacidosis in Patients With Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-15
Completion: 2025-11-01
Conditions
Diabetic Ketoacidosis
Interventions
DEVICE OTHER
No Results Yet
NCT06468228 | RECRUITING | PHASE3
1280 Participants

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-27
Completion: 2026-12-31
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
NCT06462235 | RECRUITING | PHASE2
48 Participants

A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-25
Completion: 2028-07-31
Conditions
Gram-negative Bacterial Infection
Interventions
DRUG
No Results Yet
NCT06446531 | RECRUITING | PHASE1
64 Participants

Prevention of Progression of Prediabetes, Obesity and CV Risk

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-11
Completion: 2027-07-31
Conditions
Pre-Diabetes Weight, Body Cardiovascular Diseases
Interventions
DRUG
No Results Yet
NCT06441604 | RECRUITING | PHASE2
30 Participants

Extended-release Buprenorphine as a Novel Low-dose Induction Strategy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-27
Completion: 2026-07-31
Conditions
Opioid Use Disorder
Interventions
DRUG
No Results Yet
NCT06434233 | RECRUITING | PHASE4
120 Participants

Opioid Use After Laparoscopic Salpingectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-04-25
Completion: 2026-11-30
Conditions
Opioid Use Post-operative Pain Sterility, Female
Interventions
DRUG
No Results Yet
NCT06434207 | RECRUITING
10 Participants

Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-31
Completion: 2025-12-31
Conditions
Congenital Heart Disease Single-ventricle Thrombosis
Interventions
OTHER
No Results Yet
NCT06430801 | RECRUITING | PHASE3
1200 Participants

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-05
Completion: 2028-10-30
Conditions
Crohn's Disease
Interventions
DRUG OTHER
No Results Yet
NCT06428396 | RECRUITING | PHASE2
120 Participants

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-27
Completion: 2027-05-05
Conditions
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT06422884 | RECRUITING | PHASE2
200 Participants

A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-15
Completion: 2026-10-31
Conditions
Idiopathic Pulmonary Fibrosis Progressive Fibrosing Interstitial Lung Disease
Interventions
DRUG
No Results Yet
NCT06422806 | RECRUITING | PHASE3
365 Participants

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-11
Completion: 2026-06-30
Conditions
Metastatic Dedifferentiated Liposarcoma Metastatic Undifferentiated Pleomorphic Sarcoma Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 Unresectable Dedifferentiated Liposarcoma Unresectable Undifferentiated Pleomorphic Sarcoma
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT06421636 | RECRUITING | PHASE2
95 Participants

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent ฮฒ-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-30
Completion: 2028-01-24
Conditions
Non-Transfusion Dependent Beta-Thalassemia (NTDT)
Interventions
DRUG
No Results Yet
NCT06418711 | TERMINATED | PHASE3
132 Participants

ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-11
Completion: 2025-11-10
Conditions
MAC Lung Disease Treatment Refractory MAC Lung Disease Mycobacterium Infections, Nontuberculous
Interventions
DRUG
No Results Yet
NCT06417775 | RECRUITING | PHASE3
496 Participants

Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-10
Completion: 2027-06-30
Conditions
Migraine
Interventions
DRUG
No Results Yet
NCT06413498 | RECRUITING | PHASE3
450 Participants

A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-23
Completion: 2028-07-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06413173 | RECRUITING | NA
160 Participants

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-07-25
Completion: 2028-09-30
Conditions
Brain Concussion Brain Trauma Attention Concentration Difficulty Brain Injuries Brain Injuries, Traumatic Neurocognitive Dysfunction Attention Impaired Memory Impairment Mild Traumatic Brain Injury Mild Cognitive Impairment Post Concussive Symptoms
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT06412666 | RECRUITING | PHASE2/PHASE3
55 Participants

A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-05-29
Completion: 2030-01-31
Conditions
Pediatric Symptomatic Obstructive Hypertrophic Cardiomyopathy
Interventions
DRUG
No Results Yet
NCT06405347 | COMPLETED | NA
612 Participants

The M-Well Inpatient Whole Health Bundle

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-12
Completion: 2025-10-22
Conditions
Patient Satisfaction
Interventions
BEHAVIORAL
No Results Yet
NCT06395415 | RECRUITING | NA
46 Participants

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-25
Completion: 2026-02-28
Conditions
Electronic Nicotine Delivery Systems Tobacco Products Cigarette Smoking
Interventions
BEHAVIORAL
No Results Yet
NCT06395103 | RECRUITING | PHASE1/PHASE2
90 Participants

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-16
Completion: 2029-03-31
Conditions
B-cell Acute Lymphoblastic Leukemia Diffuse Large B-cell Lymphoma Burkitt Lymphoma Neuroblastoma Ewing Sarcoma
Interventions
BIOLOGICAL
No Results Yet
NCT06386315 | RECRUITING | PHASE2
112 Participants

Reduced Dose Radiotherapy for the Treatment of Indolent Non-Hodgkin Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-05-15
Completion: 2026-05-30
Conditions
Indolent B-Cell Non-Hodgkin Lymphoma Recurrent Indolent B-Cell Non-Hodgkin Lymphoma Refractory Indolent B-Cell Non-Hodgkin Lymphoma Recurrent Indolent Non-Hodgkin Lymphoma Refractory Indolent Non-Hodgkin Lymphoma
Interventions
PROCEDURE RADIATION OTHER
No Results Yet
NCT06384573 | ACTIVE_NOT_RECRUITING | PHASE3
43 Participants

DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-10
Completion: 2030-06-30
Conditions
Alzheimer's Disease Dementia Alzheimer's Disease, Familial
Interventions
DRUG
No Results Yet
NCT06380322 | RECRUITING
650 Participants

Military Health and Nutrition Examination Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-24
Completion: 2026-12-01
Conditions
Hypertension Type 2 Diabetes Dyslipidemias Cardiovascular Diseases
No Results Yet
NCT06369285 | RECRUITING | PHASE2
150 Participants

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-19
Completion: 2027-06-30
Conditions
Hormone Receptor Positive HER-2 Negative Breast Cancer Metastatic Breast Cancer Recurrent Breast Cancer
Interventions
DRUG
No Results Yet
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