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Clinical Trials

NCT05947851 | RECRUITING | PHASE3
735 Participants

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-08-08
Completion: 2032-06-01
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell Leukemia, Chronic Lymphocytic Small-Cell Lymphoma Lymphoma, Small Lymphocytic CLL SLL
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05946941 | RECRUITING | PHASE3
756 Participants

A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-09-11
Completion: 2026-11-18
Conditions
Sjögren's Syndrome
Interventions
DRUG OTHER
No Results Yet
NCT05939414 | RECRUITING | PHASE3
450 Participants

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-03-12
Completion: 2028-04-25
Conditions
Oligometastatic Prostate Cancer (OMPC)
Interventions
DRUG
No Results Yet
NCT05936996 | COMPLETED
258 Participants

Prospective Clinical Registry Evaluating Contemporary MANTA Outcomes

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-15
Completion: 2025-06-20
Conditions
Femoral Arteriotomy Closure
Interventions
DEVICE
No Results Yet
NCT05935748 | TERMINATED | PHASE2
18 Participants

Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-07-28
Completion: 2025-06-30
Conditions
ccRCC Clear Cell Renal Cell Carcinoma Kidney Cancer Kidney Neoplasms Renal Cancer Renal Neoplasms Recurrent Renal Cell Carcinoma Metastatic Renal Cell Carcinoma Refractory Renal Cell Carcinoma Advanced Renal Cell Carcinoma Carcinoma Neoplasms Carcinoma, Renal Cell Neoplasms, Glandular and Epithelial Neoplasm by Histology Adenocarcinoma Urologic Neoplasms Urogenital Neoplasms Neoplasms by Site Kidney Diseases Urologic Diseases
Interventions
DRUG OTHER
No Results Yet
NCT05916313 | ACTIVE_NOT_RECRUITING | PHASE1
18 Participants

A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-30
Completion: 2026-02-23
Conditions
Glioma
Interventions
DRUG
No Results Yet
NCT05906095 | ENROLLING_BY_INVITATION | NA
10160 Participants

Pragmatic Trial to Increase Quality of Care in State Veterans Homes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-08
Completion: 2026-07-31
Conditions
Long-Term Care Accidental Falls
Interventions
BEHAVIORAL
No Results Yet
NCT05896267 | COMPLETED | NA
64 Participants

SpO2 Data Collection in Pediatric Patients Using INVSENSOR00061

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-05-15
Completion: 2023-06-22
Conditions
Spo2
Interventions
DEVICE
Results Available
NCT05892393 | RECRUITING | PHASE1
20 Participants

Imaging Study of [89Zr]DFO-YS5 for Detecting CD46 Positive Malignancy in Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-06-16
Completion: 2026-08-01
Conditions
Multiple Myeloma Plasma Cell Myeloma
Interventions
DRUG PROCEDURE OTHER
No Results Yet
NCT05889988 | ACTIVE_NOT_RECRUITING
36 Participants

A Study of Ado-trastuzumab Emtansine (T-DM1)-Induced Peripheral Neuropathy in HER2-positive Breast Cancer Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-06-12
Completion: 2026-06-30
Conditions
Breast Neoplasm
No Results Yet
NCT05882058 | RECRUITING | PHASE2
174 Participants

DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-10-13
Completion: 2026-10-30
Conditions
Small Cell Lung Carcinoma Neuroendocrine Neoplasms Extra-pulmonary Neuroendocrine Carcinoma
Interventions
DRUG
No Results Yet
NCT05879835 | RECRUITING | NA
124 Participants

KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children With Intestinal Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-21
Completion: 2026-06-30
Conditions
Pediatric Intestinal Failure
Interventions
DEVICE
No Results Yet
NCT05855109 | COMPLETED
1304 Participants

Developing a Screening Tool for Interstitial Lung Disease in People With Rheumatoid Arthritis Using Risk Factors

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-27
Completion: 2025-06-19
Conditions
Arthritis, Rheumatoid Lung Diseases, Interstitial
No Results Yet
NCT05853367 | RECRUITING | PHASE1
178 Participants

Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-07-06
Completion: 2028-02-12
Conditions
Metastatic Solid Tumors Advanced Solid Tumors
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05852210 | ACTIVE_NOT_RECRUITING
30 Participants

Forward Looking InfraRed Imaging and Severity Score in Complex Regional Pain Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-04-01
Completion: 2025-12-01
Conditions
CRPS (Complex Regional Pain Syndromes)
Interventions
OTHER
No Results Yet
NCT05839951 | COMPLETED
818 Participants

An Observational Study Called STAR-T to Learn More About the Sequential Treatment With Regorafenib and TAS-102 in Adults With Metastatic Colorectal Cancer Under Real World Conditions

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-04-24
Completion: 2025-04-30
Conditions
Metastatic Colorectal Cancer (mCRC)
Interventions
DRUG
No Results Yet
NCT05831085 | RECRUITING | NA
1500 Participants

Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-14
Completion: 2027-06-30
Conditions
Coronary Artery Stenosis
Interventions
PROCEDURE
No Results Yet
NCT05811754 | ACTIVE_NOT_RECRUITING
2844 Participants

Safety of Herpes Zoster Subunit (HZ/su) Vaccine During Pregnancy in Adult Women With Immunocompromised Conditions

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2022-05-09
Completion: 2028-03-31
Conditions
Herpes Zoster
Interventions
OTHER
No Results Yet
NCT05805826 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
779 Participants

To Understand the Safety and Effects of a C. Difficile Vaccine With New Adds-Ons That Will Be Given to Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-03-23
Completion: 2031-06-19
Conditions
Clostridoides Difficile Associated Disease
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT05802173 | COMPLETED | PHASE2
71 Participants

Study of TDM-105795 Following Topical Administration in Male Subjects With Androgenetic Alopecia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-03-06
Completion: 2023-11-08
Conditions
Alopecia, Androgenetic
Interventions
DRUG
Results Available
NCT05774600 | COMPLETED | NA
1120 Participants

Virtual Sun Safe Workplaces Ph II (SSW Works)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-06-01
Completion: 2025-02-25
Conditions
Skin Cancer Occupational Exposure
Interventions
BEHAVIORAL
No Results Yet
NCT05773274 | RECRUITING | PHASE2
100 Participants

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-12
Completion: 2026-04-30
Conditions
Metastatic Digestive System Neuroendocrine Tumor G1 Metastatic Digestive System Neuroendocrine Tumor G2 Unresectable Digestive System Neuroendocrine Tumor G1 Unresectable Digestive System Neuroendocrine Tumor G2
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT05769777 | RECRUITING | PHASE2
901 Participants

Open Label, Long-term Study Evaluating Safety and Efficacy of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-04-03
Completion: 2031-06-11
Conditions
Dermatitis Atopic
Interventions
DRUG
No Results Yet
NCT05759013 | ENROLLING_BY_INVITATION | NA
272 Participants

Pivotal Evaluation of Abdominal Neuromuscular Electrical Stimulation (VentFree) for Weaning From Mechanical Ventilation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-15
Completion: 2025-12-31
Conditions
Respiration, Artificial Ventilators, Mechanical
Interventions
DEVICE
No Results Yet
NCT05757141 | RECRUITING | PHASE1/PHASE2
50 Participants

An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-03-13
Completion: 2027-11-30
Conditions
Vanishing White Matter Disease
Interventions
DRUG
No Results Yet
NCT05741853 | RECRUITING | NA
60 Participants

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-05-01
Completion: 2027-11-30
Conditions
Primary Progressive Aphasia Dementia Dementia, Frontotemporal Alzheimer Disease Neurodegenerative Diseases Frontotemporal Lobar Degeneration Apraxia, Motor Dysarthria Communication Disorders Language Disorders Speech Disorders Neurocognitive Disorders Aphasia Bilingual Aphasia
Interventions
BEHAVIORAL
No Results Yet
NCT05741528 | COMPLETED | PHASE3
75 Participants

An Extension Study to a Clinical Study That Will Continue to Evaluate the Effectiveness and Safety of SEP-363856 in People With Schizophrenia That Switch to SEP-363856 From Their From Their Current Antipsychotic Medication

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-03-31
Completion: 2024-09-23
Conditions
Schizophrenia
Interventions
DRUG
Results Available
NCT05738824 | RECRUITING
500 Participants

Natural History of Inflammatory Muscle Diseases

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-06-01
Completion: 2032-02-25
Conditions
Inflammation In Skeletal Muscle
No Results Yet
NCT05731141 | RECRUITING
1200 Participants

A Prospective Natural History Study of Lymphatic Anomalies

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-03-20
Completion: 2026-12-31
Conditions
Lymphatic Diseases Lymphatic Abnormalities
No Results Yet
NCT05719441 | RECRUITING | PHASE2
48 Participants

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-19
Completion: 2028-04-06
Conditions
Acute HIV Infection
Interventions
BIOLOGICAL OTHER DRUG
No Results Yet
NCT05695027 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
250 Participants

Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-03-14
Completion: 2026-06-30
Conditions
Primary Open Angle Glaucoma
Interventions
DRUG
No Results Yet
NCT05691478 | RECRUITING | PHASE2/PHASE3
1122 Participants

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-03-03
Completion: 2030-03-20
Conditions
High Grade Osteosarcoma Localized Osteosarcoma Metastatic Osteosarcoma Secondary Osteosarcoma
Interventions
PROCEDURE DRUG
No Results Yet
NCT05686070 | COMPLETED | PHASE3
12327 Participants

A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-01-26
Completion: 2025-10-23
Conditions
Prevention of Ischemic Stroke Acute Non-cardioembolic Ischemic Stroke High-risk Transient Ischemic Attack
Interventions
DRUG
No Results Yet
NCT05672316 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
28 Participants

Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-05-11
Completion: 2025-05-10
Conditions
Advanced Colorectal Adenocarcinoma Advanced Microsatellite Stable Colorectal Carcinoma Metastatic Colorectal Adenocarcinoma Metastatic Microsatellite Stable Colorectal Carcinoma Stage III Colorectal Cancer AJCC v8 Stage IV Colorectal Cancer AJCC v8
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT05663866 | ACTIVE_NOT_RECRUITING | PHASE2
68 Participants

Premedication to Reduce Amivantamab Associated Infusion Related Reactions

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-05-18
Completion: 2024-03-29
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
Results Available
NCT05648968 | RECRUITING | PHASE3
90 Participants

A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-12-30
Completion: 2026-03-02
Conditions
Warm Autoimmune Hemolytic Anemia (wAIHA)
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT05642325 | ACTIVE_NOT_RECRUITING | PHASE3
256 Participants

Vamikibart in Participants With Uveitic Macular Edema

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-03-23
Completion: 2025-05-07
Conditions
Uveitic Macular Edema
Interventions
DRUG OTHER
No Results Yet
NCT05640102 | RECRUITING
111 Participants

Observational Study Evaluating the Efficacy and Safety of Zanubrutinib in Participants With Waldenström Macroglobulinemia

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-03-03
Completion: 2026-12-31
Conditions
Waldenstrom Macroglobulinemia
Interventions
DRUG
No Results Yet
NCT05634369 | RECRUITING | PHASE1/PHASE2
50 Participants

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-11-14
Completion: 2026-12-01
Conditions
Pediatric Sarcoma, Refractory Pediatric Sarcoma, Relapsed
Interventions
BIOLOGICAL
No Results Yet
NCT05633667 | RECRUITING | PHASE2
593 Participants

Study of Novel Treatment Combinations in Patients With Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-03-16
Completion: 2029-09-30
Conditions
Lung Cancer Advanced or Metastatic Non-Small-Cell Lung Cancer Resectable Non-Small-Cell Lung Cancer
Interventions
DRUG
No Results Yet
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