Clinical Trials
101
Participants
A Clinical Study That Will Evaluate How Well SEP-363856 Works and How Safe it is in People With Schizophrenia That Switch to SEP-363856 From Their Current Antipsychotic Medication
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-12-19
Completion:
2024-04-01
Conditions
Schizophrenia
Interventions
DRUG
966
Participants
A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135), Daratumumab, Lenalidomide or Elranatamab and Lenalidomide Compared With Daratumumab, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-11-10
Completion:
2028-03-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
614
Participants
Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-02-06
Completion:
2027-01-12
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL
No Results Yet
182
Participants
Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-11-25
Completion:
2026-02-25
Conditions
Colitis Ulcerative
Interventions
DRUG
No Results Yet
45155
Participants
Suicide Prevention for Justice Involved Managed Care Subscribers
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-09-01
Completion:
2024-09-03
Conditions
Suicide and Self-harm
Interventions
BEHAVIORAL
15
Participants
Withdrawal of Tiratricol Treatment in Males With Monocarboxylate Transporter 8 Deficiency (MCT8 Deficiency)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-07-21
Completion:
2025-09-03
Conditions
Monocarboxylate Transporter 8 Deficiency
Allan-Herndon-Dudley Syndrome
Interventions
DRUG
No Results Yet
84
Participants
A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-09-30
Completion:
2026-09-30
Conditions
Solid Tumor
Metastatic Cancer
Interventions
DRUG
RADIATION
No Results Yet
34
Participants
Remote Cognitive Assessment for Surgical Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2022-06-29
Completion:
2024-02-29
Conditions
Mild Cognitive Impairment
Delirium
No Results Yet
214
Participants
A Study in People With Systemic Sclerosis to Test Whether Avenciguat (BI 685509) Has an Effect on Lung Function and Other Systemic Sclerosis Symptoms
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-12-13
Completion:
2025-10-22
Conditions
Scleroderma, Systemic
Interventions
DRUG
No Results Yet
153
Participants
Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-09-13
Completion:
2025-12-31
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
PROCEDURE
No Results Yet
280
Participants
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-11-22
Completion:
2034-03-30
Conditions
Alzheimers Disease
Dementia
Alzheimers Disease, Familial
Interventions
DRUG
No Results Yet
26
Participants
Trial of Suvorexant for Sleep in Children With Autism
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-08-09
Completion:
2028-02-28
Conditions
Autism
Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
76
Participants
A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-10-24
Completion:
2027-01-31
Conditions
Duchenne Muscular Dystrophy
Interventions
DRUG
No Results Yet
26
Participants
Trial of Zolpidem for Sleep in Children With Autism
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-08-09
Completion:
2028-04-30
Conditions
Autism
Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
124
Participants
A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-11-30
Completion:
2027-02-02
Conditions
Melanoma
Glioma
Thyroid Cancer
Non-Small Cell Lung Cancer
Malignant Neoplasms
Brain Neoplasms
Colorectal Cancer
Interventions
DRUG
No Results Yet
90
Participants
A Study Evaluating the Efficacy and Safety of Cevostamab in Prior B Cell Maturation Antigen (BCMA)-Exposed Participants With Relapsed/Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-10-17
Completion:
2027-02-26
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
20
Participants
A Study of Imlunestrant (LY3484356) in Healthy Women
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-09-12
Completion:
2022-11-30
Conditions
Healthy
Interventions
DRUG
26
Participants
Trial of Diphenhydramine for Sleep in Children With Autism
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-08-09
Completion:
2027-12-31
Conditions
Autism
Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
102
Participants
JAB-2485 Activity in Adult Patients With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-12-20
Completion:
2026-08-31
Conditions
Solid Tumors
ER+ Breast Cancer
Triple Negative Breast Cancer, TNBC
ARID1A Gene Mutation
Small Cell Lung Cancer, SCLC
Interventions
DRUG
No Results Yet
40
Participants
An Intervention to Enhance Well-Being in Trauma Exposed New Mothers
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-02-13
Completion:
2025-09-01
Conditions
Post-traumatic Stress Disorder
Dissociation
Maternal Care Patterns
Infant Behavior
Maternal Behavior
Maternal Distress
Mood Disturbance
Emotional Regulation
Interventions
DEVICE
No Results Yet
100
Participants
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-11-08
Completion:
2029-01-28
Conditions
Chronic Kidney Disease
Proteinuria
Children
Interventions
DRUG
No Results Yet
27
Participants
A Study of Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-07-05
Completion:
2024-02-28
Conditions
Hepatic Insufficiency
Healthy
Interventions
DRUG
1000
Participants
An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-12-01
Completion:
2026-05-31
Conditions
BRCA1 Mutation
POLD1 Gene Mutation
CDKN2A Mutation
BRCA2 Mutation
POLE Gene Mutation
APC Gene Mutation
ATM Gene Mutation
MLH1 Gene Mutation
BARD1 Gene Mutation
MSH2 Gene Mutation
BRIP1 Gene Mutation
MSH6 Gene Mutation
CHEK2 Gene Mutation
PMS2 Gene Mutation
PALB2 Gene Mutation
EPCAM Gene Mutation
RAD51C Gene Mutation
BMPR1A Gene Mutation
RAD51D Gene Mutation
SMAD4
PTEN Gene Mutation
GREM1
Interventions
BEHAVIORAL
No Results Yet
346
Participants
A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-07-05
Completion:
2024-11-20
Conditions
Early Breast Cancer
Locally Advanced Breast Cancer
Inflammatory Breast Cancer
Interventions
DRUG
PROCEDURE
RADIATION
No Results Yet
4000
Participants
Natural History Protocol for Movement Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2022-10-17
Completion:
2030-12-31
Conditions
Movement Disorder
Tremor
Parkinson's Disease
No Results Yet
70
Participants
Care Planning Framework in Advanced Cancer (ABC123)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-02-15
Completion:
2025-12-22
Conditions
Advanced Cancer
Interventions
BEHAVIORAL
No Results Yet
12
Participants
Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-09-09
Completion:
2025-12-31
Conditions
Colorectal Cancer
Hematologic Malignancy
Rectum Cancer
Acute Myeloid Leukemia
Myelodysplastic Syndromes
Acute Lymphoblastic Leukemia
Chronic Myeloid Leukemia
Chronic Lymphocytic Leukemia
Hodgkin Lymphoma
Non Hodgkin Lymphoma
Myeloproliferative Syndrome
Plasma Cell Myeloma
Gastric Cancer
Esophageal Cancer
Esophagus Cancer
Gastric Cancer, Metastatic
Unresectable Esophageal Cancer
Metastatic Esophageal Cancer
Interventions
DRUG
No Results Yet
100
Participants
Neurofeedback for Borderline Personality Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-09-02
Completion:
2026-04-30
Conditions
Borderline Personality Disorder
Interventions
DEVICE
No Results Yet
754
Participants
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-05-31
Completion:
2027-05-31
Conditions
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Pancreatic Ductal Adenocarcinoma (PDAC)
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
82
Participants
Intergenerational Transmission of Low-calorie Sweeteners Via Breast Milk
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-02-28
Completion:
2022-12-02
Conditions
Breastfeeding
Interventions
OTHER
700
Participants
Met Non Small Cell Cancer Registry (MOMENT)
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2022-10-04
Completion:
2028-04-28
Conditions
Cancer
No Results Yet
156
Participants
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-07-05
Completion:
2027-03-28
Conditions
Melanoma
Non-Small-Cell Lung Cancer
Thyroid Cancer
Glioma
Interventions
DRUG
BIOLOGICAL
No Results Yet
4500
Participants
A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2022-06-13
Completion:
2026-09-30
Conditions
Chronic Kidney Disease
Type 2 Diabetes Mellitus
Interventions
DRUG
No Results Yet
12
Participants
Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-06-23
Completion:
2026-03-31
Conditions
Neuromyelitis Optica Spectrum Disorder
Interventions
DRUG
No Results Yet
90
Participants
Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-11-01
Completion:
2026-12-31
Conditions
Asherman Syndrome
Atrophic Endometrium
Recurrent Implantation Failure
Interventions
DRUG
No Results Yet
8
Participants
CPI-613 (Devimistat) in Combination With Chemoradiation in Patients With Pancreatic Adenocarcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-10-31
Completion:
2025-07-08
Conditions
Pancreas Adenocarcinoma
Interventions
DRUG
RADIATION
No Results Yet
21
Participants
Self-Care for Dementia Caregivers
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-03-07
Completion:
2024-12-01
Conditions
Aging
Mental Disorder
Eating, Healthy
Physical Inactivity
Prodromal Symptoms
Sleep
Alzheimer Disease
Dementia
Circadian Rhythm Disorders
Interventions
BEHAVIORAL
No Results Yet
373
Participants
A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-08-03
Completion:
2025-07-16
Conditions
Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
28
Participants
A Study to Evaluate the Effect of Spinal Cord Stimulation (SCS) on Painful Diabetic Peripheral Neuropathy (pDPN)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-09-22
Completion:
2026-04-30
Conditions
Chronic Pain
Interventions
DEVICE
No Results Yet
197
Participants
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-12-22
Completion:
2028-04-30
Conditions
Alzheimers Disease
Dementia
Alzheimers Disease, Familial
Interventions
DRUG
No Results Yet
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