Clinical Trials

NCT05566275 | COMPLETED
34 Participants

Remote Cognitive Assessment for Surgical Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2022-06-29
Completion: 2024-02-29
Conditions
Mild Cognitive Impairment Delirium
No Results Yet
NCT05559580 | ACTIVE_NOT_RECRUITING | PHASE2
214 Participants

A Study in People With Systemic Sclerosis to Test Whether Avenciguat (BI 685509) Has an Effect on Lung Function and Other Systemic Sclerosis Symptoms

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-12-13
Completion: 2025-10-22
Conditions
Scleroderma, Systemic
Interventions
DRUG
No Results Yet
NCT05554393 | RECRUITING | PHASE2
153 Participants

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-13
Completion: 2025-12-31
Conditions
Acute Myeloid Leukemia
Interventions
DRUG PROCEDURE
No Results Yet
NCT05552157 | RECRUITING | PHASE2/PHASE3
280 Participants

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-22
Completion: 2034-03-30
Conditions
Alzheimers Disease Dementia Alzheimers Disease, Familial
Interventions
DRUG
No Results Yet
NCT05546554 | RECRUITING | PHASE2
26 Participants

Trial of Suvorexant for Sleep in Children With Autism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-08-09
Completion: 2028-02-28
Conditions
Autism Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
NCT05540860 | ACTIVE_NOT_RECRUITING | PHASE2
76 Participants

A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-10-24
Completion: 2027-01-31
Conditions
Duchenne Muscular Dystrophy
Interventions
DRUG
No Results Yet
NCT05540574 | RECRUITING | PHASE2
26 Participants

Trial of Zolpidem for Sleep in Children With Autism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-08-09
Completion: 2028-04-30
Conditions
Autism Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
NCT05538130 | RECRUITING | PHASE1
124 Participants

A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-11-30
Completion: 2027-02-02
Conditions
Melanoma Glioma Thyroid Cancer Non-Small Cell Lung Cancer Malignant Neoplasms Brain Neoplasms Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT05535244 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
90 Participants

A Study Evaluating the Efficacy and Safety of Cevostamab in Prior B Cell Maturation Antigen (BCMA)-Exposed Participants With Relapsed/Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-10-17
Completion: 2027-02-26
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05509816 | COMPLETED | PHASE1
20 Participants

A Study of Imlunestrant (LY3484356) in Healthy Women

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-09-12
Completion: 2022-11-30
Conditions
Healthy
Interventions
DRUG
NCT05501678 | RECRUITING | PHASE2
26 Participants

Trial of Diphenhydramine for Sleep in Children With Autism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-08-09
Completion: 2027-12-31
Conditions
Autism Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
NCT05490472 | RECRUITING | PHASE1/PHASE2
102 Participants

JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-12-20
Completion: 2026-08-31
Conditions
Solid Tumors ER+ Breast Cancer Triple Negative Breast Cancer, TNBC ARID1A Gene Mutation Small Cell Lung Cancer, SCLC
Interventions
DRUG
No Results Yet
NCT05474534 | ACTIVE_NOT_RECRUITING | NA
40 Participants

An Intervention to Enhance Well-Being in Trauma Exposed New Mothers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-02-13
Completion: 2025-09-01
Conditions
Post-traumatic Stress Disorder Dissociation Maternal Care Patterns Infant Behavior Maternal Behavior Maternal Distress Mood Disturbance Emotional Regulation
Interventions
DEVICE
No Results Yet
NCT05457283 | RECRUITING | PHASE3
100 Participants

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-11-08
Completion: 2029-01-28
Conditions
Chronic Kidney Disease Proteinuria Children
Interventions
DRUG
No Results Yet
NCT05440344 | COMPLETED | PHASE1
27 Participants

A Study of Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-07-05
Completion: 2024-02-28
Conditions
Hepatic Insufficiency Healthy
Interventions
DRUG
NCT05420064 | RECRUITING | NA
1000 Participants

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-12-01
Completion: 2026-05-31
Conditions
BRCA1 Mutation POLD1 Gene Mutation CDKN2A Mutation BRCA2 Mutation POLE Gene Mutation APC Gene Mutation ATM Gene Mutation MLH1 Gene Mutation BARD1 Gene Mutation MSH2 Gene Mutation BRIP1 Gene Mutation MSH6 Gene Mutation CHEK2 Gene Mutation PMS2 Gene Mutation PALB2 Gene Mutation EPCAM Gene Mutation RAD51C Gene Mutation BMPR1A Gene Mutation RAD51D Gene Mutation SMAD4 PTEN Gene Mutation GREM1
Interventions
BEHAVIORAL
No Results Yet
NCT05415215 | COMPLETED | PHASE3
346 Participants

A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-07-05
Completion: 2024-11-20
Conditions
Early Breast Cancer Locally Advanced Breast Cancer Inflammatory Breast Cancer
Interventions
DRUG PROCEDURE RADIATION
No Results Yet
NCT05413291 | RECRUITING
4000 Participants

Natural History Protocol for Movement Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2022-10-17
Completion: 2030-12-31
Conditions
Movement Disorder Tremor Parkinson's Disease
No Results Yet
NCT05408507 | ACTIVE_NOT_RECRUITING | NA
70 Participants

Care Planning Framework in Advanced Cancer (ABC123)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-02-15
Completion: 2025-12-22
Conditions
Advanced Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT05400122 | SUSPENDED | PHASE1
12 Participants

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-09-09
Completion: 2025-12-31
Conditions
Colorectal Cancer Hematologic Malignancy Rectum Cancer Acute Myeloid Leukemia Myelodysplastic Syndromes Acute Lymphoblastic Leukemia Chronic Myeloid Leukemia Chronic Lymphocytic Leukemia Hodgkin Lymphoma Non Hodgkin Lymphoma Myeloproliferative Syndrome Plasma Cell Myeloma Gastric Cancer Esophageal Cancer Esophagus Cancer Gastric Cancer, Metastatic Unresectable Esophageal Cancer Metastatic Esophageal Cancer
Interventions
DRUG
No Results Yet
NCT05398627 | ACTIVE_NOT_RECRUITING | NA
100 Participants

Neurofeedback for Borderline Personality Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-09-02
Completion: 2026-04-30
Conditions
Borderline Personality Disorder
Interventions
DEVICE
No Results Yet
NCT05379985 | RECRUITING | PHASE1/PHASE2
754 Participants

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-05-31
Completion: 2027-05-31
Conditions
Non-small Cell Lung Cancer (NSCLC) Colorectal Cancer (CRC) Pancreatic Ductal Adenocarcinoma (PDAC) Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT05379270 | COMPLETED | NA
82 Participants

Intergenerational Transmission of Low-calorie Sweeteners Via Breast Milk

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-02-28
Completion: 2022-12-02
Conditions
Breastfeeding
Interventions
OTHER
NCT05376891 | RECRUITING
700 Participants

Met Non Small Cell Cancer Registry (MOMENT)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2022-10-04
Completion: 2028-04-28
Conditions
Cancer
No Results Yet
NCT05355701 | RECRUITING | PHASE1
156 Participants

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-07-05
Completion: 2027-03-28
Conditions
Melanoma Non-Small-Cell Lung Cancer Thyroid Cancer Glioma
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05348733 | RECRUITING
4500 Participants

A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2022-06-13
Completion: 2026-09-30
Conditions
Chronic Kidney Disease Type 2 Diabetes Mellitus
Interventions
DRUG
No Results Yet
NCT05346354 | RECRUITING | PHASE2/PHASE3
12 Participants

Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-06-23
Completion: 2026-03-31
Conditions
Neuromyelitis Optica Spectrum Disorder
Interventions
DRUG
No Results Yet
NCT05343572 | RECRUITING | EARLY_PHASE1
90 Participants

Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-01
Completion: 2026-12-31
Conditions
Asherman Syndrome Atrophic Endometrium Recurrent Implantation Failure
Interventions
DRUG
No Results Yet
NCT05325281 | TERMINATED | PHASE1
8 Participants

CPI-613 (Devimistat) in Combination With Chemoradiation in Patients With Pancreatic Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-10-31
Completion: 2025-07-08
Conditions
Pancreas Adenocarcinoma
Interventions
DRUG RADIATION
No Results Yet
NCT05306340 | ACTIVE_NOT_RECRUITING | PHASE3
373 Participants

A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-08-03
Completion: 2025-07-16
Conditions
Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT05302063 | ACTIVE_NOT_RECRUITING | NA
28 Participants

A Study to Evaluate the Effect of Spinal Cord Stimulation (SCS) on Painful Diabetic Peripheral Neuropathy (pDPN)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-09-22
Completion: 2026-04-30
Conditions
Chronic Pain
Interventions
DEVICE
No Results Yet
NCT05269394 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
197 Participants

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-12-22
Completion: 2028-04-30
Conditions
Alzheimers Disease Dementia Alzheimers Disease, Familial
Interventions
DRUG
No Results Yet
NCT05261633 | RECRUITING
80 Participants

Diffusion MRI of the Abdomen

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-22
Completion: 2026-06-30
Conditions
Abdominal Imaging
Interventions
DEVICE
No Results Yet
NCT05256303 | COMPLETED | NA
160 Participants

Rural Hospital-Level Care at Home for Acutely Ill Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-02-16
Completion: 2023-12-17
Conditions
Infections Heart Failure Chronic Obstructive Pulmonary Disease Asthma Gout Flare Chronic Kidney Diseases Hypertensive Urgency Atrial Fibrillation Rapid Anticoagulation Diabetes and Its Complications End of Life/Desires Only Medical Management
Interventions
OTHER
No Results Yet
NCT05256225 | RECRUITING | PHASE3
360 Participants

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-11-16
Completion: 2027-10-31
Conditions
Endometrial Carcinoma Endometrial Clear Cell Adenocarcinoma Endometrial Dedifferentiated Carcinoma Endometrial Endometrioid Adenocarcinoma Endometrial Mixed Cell Adenocarcinoma Endometrial Serous Adenocarcinoma Endometrial Undifferentiated Carcinoma Uterine Corpus Carcinosarcoma
Interventions
PROCEDURE DRUG RADIATION OTHER
No Results Yet
NCT05239741 | RECRUITING | PHASE3
100 Participants

Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-04-02
Completion: 2028-09-19
Conditions
Colorectal Neoplasms
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT05237934 | RECRUITING
300 Participants

Tissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2022-04-25
Completion: 2032-12-31
Conditions
Neuroendocrine Tumors Carcinoma, Neuroendocrine
No Results Yet
NCT05236010 | RECRUITING | NA
108 Participants

Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-01-21
Completion: 2026-04-01
Conditions
Traumatic Brain Injury
Interventions
DEVICE OTHER
No Results Yet
NCT05231785 | RECRUITING | PHASE1
60 Participants

A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-02-04
Completion: 2029-03-28
Conditions
Early-Onset Alzheimer Disease
Interventions
DRUG
No Results Yet
NCT05224336 | RECRUITING | PHASE1
20 Participants

Psilocybin-assisted Therapy for Phantom Limb Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-10-03
Completion: 2024-03-07
Conditions
Phantom Limb Pain
Interventions
DRUG
No Results Yet
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