Clinical Trials

Showing trials with last updates posted in 2025.

NCT05355701 | RECRUITING | PHASE1
156 Participants

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-07-05
Completion: 2027-03-28
Conditions
Melanoma Non-Small-Cell Lung Cancer Thyroid Cancer Glioma
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05348733 | RECRUITING
4500 Participants

A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2022-06-13
Completion: 2026-09-30
Conditions
Chronic Kidney Disease Type 2 Diabetes Mellitus
Interventions
DRUG
No Results Yet
NCT05346354 | RECRUITING | PHASE2/PHASE3
12 Participants

Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-06-23
Completion: 2026-03-31
Conditions
Neuromyelitis Optica Spectrum Disorder
Interventions
DRUG
No Results Yet
NCT05343572 | RECRUITING | EARLY_PHASE1
90 Participants

Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-01
Completion: 2026-12-31
Conditions
Asherman Syndrome Atrophic Endometrium Recurrent Implantation Failure
Interventions
DRUG
No Results Yet
NCT05325281 | TERMINATED | PHASE1
8 Participants

CPI-613 (Devimistat) in Combination With Chemoradiation in Patients With Pancreatic Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-10-31
Completion: 2025-07-08
Conditions
Pancreas Adenocarcinoma
Interventions
DRUG RADIATION
No Results Yet
NCT05309577 | COMPLETED | NA
21 Participants

Self-Care for Dementia Caregivers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-03-07
Completion: 2024-12-01
Conditions
Aging Mental Disorder Eating, Healthy Physical Inactivity Prodromal Symptoms Sleep Alzheimer Disease Dementia Circadian Rhythm Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT05306340 | ACTIVE_NOT_RECRUITING | PHASE3
373 Participants

A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-08-03
Completion: 2025-07-16
Conditions
Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT05302063 | ACTIVE_NOT_RECRUITING | NA
28 Participants

A Study to Evaluate the Effect of Spinal Cord Stimulation (SCS) on Painful Diabetic Peripheral Neuropathy (pDPN)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-09-22
Completion: 2026-04-30
Conditions
Chronic Pain
Interventions
DEVICE
No Results Yet
NCT05269394 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
197 Participants

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-12-22
Completion: 2028-04-30
Conditions
Alzheimers Disease Dementia Alzheimers Disease, Familial
Interventions
DRUG
No Results Yet
NCT05261633 | RECRUITING
80 Participants

Diffusion MRI of the Abdomen

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-22
Completion: 2026-06-30
Conditions
Abdominal Imaging
Interventions
DEVICE
No Results Yet
NCT05256303 | COMPLETED | NA
160 Participants

Rural Hospital-Level Care at Home for Acutely Ill Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-02-16
Completion: 2023-12-17
Conditions
Infections Heart Failure Chronic Obstructive Pulmonary Disease Asthma Gout Flare Chronic Kidney Diseases Hypertensive Urgency Atrial Fibrillation Rapid Anticoagulation Diabetes and Its Complications End of Life/Desires Only Medical Management
Interventions
OTHER
No Results Yet
NCT05256225 | RECRUITING | PHASE3
360 Participants

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-11-16
Completion: 2027-10-31
Conditions
Endometrial Carcinoma Endometrial Clear Cell Adenocarcinoma Endometrial Dedifferentiated Carcinoma Endometrial Endometrioid Adenocarcinoma Endometrial Mixed Cell Adenocarcinoma Endometrial Serous Adenocarcinoma Endometrial Undifferentiated Carcinoma Uterine Corpus Carcinosarcoma
Interventions
PROCEDURE DRUG RADIATION OTHER
No Results Yet
NCT05239741 | RECRUITING | PHASE3
100 Participants

Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-04-02
Completion: 2028-09-19
Conditions
Colorectal Neoplasms
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT05237934 | RECRUITING
300 Participants

Tissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2022-04-25
Completion: 2032-12-31
Conditions
Neuroendocrine Tumors Carcinoma, Neuroendocrine
No Results Yet
NCT05236010 | RECRUITING | NA
108 Participants

Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-01-21
Completion: 2026-04-01
Conditions
Traumatic Brain Injury
Interventions
DEVICE OTHER
No Results Yet
NCT05231785 | RECRUITING | PHASE1
60 Participants

A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-02-04
Completion: 2029-03-28
Conditions
Early-Onset Alzheimer Disease
Interventions
DRUG
No Results Yet
NCT05224336 | RECRUITING | PHASE1
20 Participants

Psilocybin-assisted Therapy for Phantom Limb Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-10-03
Completion: 2024-03-07
Conditions
Phantom Limb Pain
Interventions
DRUG
No Results Yet
NCT05210114 | RECRUITING | NA
30 Participants

Cutaneous Hydration Assessment in SCD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-01-21
Completion: 2026-12-31
Conditions
Sickle Cell Disease
Interventions
DEVICE
No Results Yet
NCT05199571 | COMPLETED | PHASE4
99 Participants

Study of Efficacy and Safety of Ofatumumab in Relapsing Multiple Sclerosis (RMS) Patients in China

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-07-22
Completion: 2025-02-13
Conditions
Relapsing Multiple Sclerosis
Interventions
BIOLOGICAL
NCT05172596 | TERMINATED | PHASE2
146 Participants

PHE885 CAR-T Therapy in Adult Participants With Relapsed and Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-03-03
Completion: 2025-05-21
Conditions
Multiple Myeloma
Interventions
BIOLOGICAL
No Results Yet
NCT05171647 | ACTIVE_NOT_RECRUITING | PHASE3
242 Participants
NCT05170412 | RECRUITING
80 Participants

Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2022-05-26
Completion: 2026-12-31
Conditions
Sickle Cell Disease
No Results Yet
NCT05161169 | COMPLETED | NA
500 Participants

Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-12-21
Completion: 2025-06-30
Conditions
Genetic Predisposition to Disease Hereditary Diseases
Interventions
GENETIC
No Results Yet
NCT05156398 | RECRUITING | PHASE3
640 Participants

Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-02-28
Completion: 2031-11-29
Conditions
Migraine
Interventions
DRUG
No Results Yet
NCT05146739 | ACTIVE_NOT_RECRUITING | PHASE1
8 Participants

Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-10-10
Completion: 2025-03-31
Conditions
Acute Myeloid Leukemia Post Cytotoxic Therapy Myelodysplastic Syndrome Post Cytotoxic Therapy Myeloid Leukemia Associated With Down Syndrome Recurrent Acute Myeloid Leukemia Recurrent Mixed Phenotype Acute Leukemia Recurrent Myelodysplastic Syndrome Refractory Acute Myeloid Leukemia Refractory Mixed Phenotype Acute Leukemia Refractory Myelodysplastic Syndrome
Interventions
DRUG
No Results Yet
NCT05145062 | ACTIVE_NOT_RECRUITING
8 Participants

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2021-12-21
Completion: 2038-07-14
Conditions
Blood and Lymphatic Diseases
Interventions
DRUG
No Results Yet
NCT05142189 | RECRUITING | PHASE1
280 Participants

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-06-17
Completion: 2030-02-28
Conditions
Non-Small Cell Lung Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT05141019 | ACTIVE_NOT_RECRUITING | NA
492 Participants

Trial of Preemptive Pharmacogenetics in Underserved Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-08-01
Completion: 2025-09-08
Conditions
Use of Prescription Medications Pharmacogenetic Testing
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05133531 | RECRUITING | PHASE3
190 Participants

A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-08-01
Completion: 2027-01-28
Conditions
Paroxysmal Nocturnal Hemoglobinuria
Interventions
DRUG
No Results Yet
NCT05119335 | TERMINATED | PHASE1/PHASE2
120 Participants

A Study of NKT2152, a HIF2ฮฑ Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-10-26
Completion: 2025-08-22
Conditions
ccRCC Clear Cell Renal Cell Carcinoma Kidney Cancer Kidney Neoplasms Renal Cancer Renal Neoplasms Recurrent Renal Cell Carcinoma Metastatic Renal Cell Carcinoma Refractory Renal Cell Carcinoma Advanced Renal Cell Carcinoma Hypoxia Renal Cell Carcinoma Hypoxia Inducible Factor (HIF) HIF2ฮฑ Inhibitor Hypoxia Inducible Factor 2 Alpha (HIF-2 Alpha) Hypoxia Inducible Factor 2ฮฑ (HIF-2ฮฑ) Clear Cell
Interventions
DRUG
No Results Yet
NCT05116163 | COMPLETED | NA
201 Participants

Breaking Implicit Bias Habits: An Individuation Pilot Study In Rheumatology

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-06-17
Completion: 2024-09-27
Conditions
Systemic Lupus Erythematosus Rheumatoid Arthritis Inflammatory Arthritis Osteoarthritis
Interventions
BEHAVIORAL OTHER
NCT05112679 | COMPLETED | NA
6 Participants

Limb Health and Socket Pressure in Response to Powered Ankle Protheses

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-11-15
Completion: 2023-07-19
Conditions
Pressure Ulcer, Ankle Prosthesis User Prosthesis Durability Mobility Limitation Skin Wound Amputation; Traumatic, Foot Amputation Limb Deficiencies
Interventions
DEVICE
NCT05109728 | RECRUITING | PHASE1
60 Participants

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-05-10
Completion: 2026-06-05
Conditions
Glioblastoma
Interventions
DRUG OTHER
No Results Yet
NCT05099965 | COMPLETED | PHASE2
90 Participants

Trial to Evaluate the Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA)-Based Anti-Cytomegalovirus (CMV) Vaccine (Triplexยฎ)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-11-02
Completion: 2024-11-08
Conditions
Cytomegalovirus Infections HIV Infections Vaccine
Interventions
BIOLOGICAL
No Results Yet
NCT05099172 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
370 Participants

First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-10-25
Completion: 2026-11-30
Conditions
Advanced Non-small Cell Lung Cancer EGFR Mutation HER2 Mutation
Interventions
DRUG
No Results Yet
NCT05099003 | RECRUITING | PHASE1/PHASE2
132 Participants

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-05-31
Completion: 2027-06-30
Conditions
Malignant Glioma
Interventions
PROCEDURE RADIATION DRUG
No Results Yet
NCT05094115 | RECRUITING | NA
600 Participants

Enhancing Resiliency and Optimizing Readiness in Military Personnel

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-10-04
Completion: 2026-09-30
Conditions
Resilience, Psychological Stress, Physiological
Interventions
BEHAVIORAL
No Results Yet
NCT05085548 | ACTIVE_NOT_RECRUITING | PHASE1
58 Participants

ProAgio in Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-10-29
Completion: 2025-12-31
Conditions
Advanced Pancreatic Cancer Solid Tumor Malignancies
Interventions
DRUG
No Results Yet
NCT05076266 | TERMINATED
14 Participants

COVID-19 Related Financial Hardship and Distress in Women Who Decline TMIST (EA1151) Participation

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2022-03-14
Completion: 2023-02-02
Conditions
Breast Cancer, NOS
Interventions
OTHER
NCT05065047 | TERMINATED | PHASE1
6 Participants

Belantamab Mafadotin Maintenance Therapy After Salvage Autologous Hematopoietic Cell Transplantation in Patients With Relapse Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-01-05
Completion: 2025-11-06
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
Previous
Sorted by latest updates
Next
Showing 40 trials per page ยท Total 107726 trials