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Clinical Trials

NCT04527549 | TERMINATED | PHASE2
5 Participants

Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-06-01
Completion: 2024-01-08
Conditions
Clinical Stage IV Cutaneous Melanoma AJCC v8 Locally Advanced Melanoma Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 Pathologic Stage IV Cutaneous Melanoma AJCC v8 Unresectable Melanoma
Interventions
DRUG
Results Available
NCT04518228 | COMPLETED
205 Participants

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2021-09-01
Completion: 2025-04-24
Conditions
HIV Infections Tuberculosis
Interventions
DRUG
No Results Yet
NCT04514861 | ACTIVE_NOT_RECRUITING | NA
53 Participants

Monitoring Local Tissue Oxygen Changes Using the Wireless Lumee Oxygen Platform in Correlation to TcPO2

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-12-18
Completion: 2027-03-30
Conditions
Peripheral Artery Disease
Interventions
DEVICE
No Results Yet
NCT04477512 | COMPLETED | PHASE1
18 Participants

Cabozantinib and Abiraterone With Checkpoint Inhibitor Immunotherapy in Metastatic Hormone Sensitive Prostate Cancer (CABIOS Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-02-19
Completion: 2021-09-09
Conditions
Metastatic Hormone Refractory Prostate Cancer
Interventions
DRUG PROCEDURE
No Results Yet
NCT04465214 | COMPLETED
49 Participants

Mobile Sensor Technologies to Assess General Symptomology of People With Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2020-11-23
Completion: 2024-04-10
Conditions
Neoplasms Solid Tumors Prostate Cancer Lung Cancer Colon Cancer
No Results Yet
NCT04440228 | COMPLETED | NA
90 Participants

TeamSTEPPS in School Mental Health

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-05-23
Completion: 2024-04-30
Conditions
Child Behavior Problem Multidisciplinary Communication Interprofessional Relations
Interventions
BEHAVIORAL
Results Available
NCT04415515 | TERMINATED | NA
592023 Participants

Standard Care Coordination Expansion Pilot

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2015-10-31
Completion: 2023-12-31
Conditions
Superutilizers, Health Care Utilization
Interventions
BEHAVIORAL
No Results Yet
NCT04384172 | COMPLETED | NA
9 Participants

Effect of Peripheral Neuromodulation on Vaginal Blood Flow

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-11-11
Completion: 2022-03-15
Conditions
Female Sexual Dysfunction Spinal Cord Injuries
Interventions
DEVICE
Results Available
NCT04375072 | COMPLETED | NA
208 Participants

Home-based tDCS and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-08-13
Completion: 2025-01-30
Conditions
Osteo Arthritis Knee
Interventions
DEVICE
Results Available
NCT04353492 | COMPLETED | PHASE3
562 Participants

An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-07-14
Completion: 2024-10-09
Conditions
Relapsing Multiple Sclerosis
Interventions
BIOLOGICAL
Results Available
NCT04349059 | RECRUITING | NA
46 Participants

The Impact of Dietary Pattern on Erectile Function

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-10-30
Completion: 2026-12-31
Conditions
Erectile Dysfunction
Interventions
OTHER
No Results Yet
NCT04325828 | ACTIVE_NOT_RECRUITING | PHASE2
31 Participants

A Study of Apalutamide Combined With GnRH Agonist in Participants With Androgen Receptor Positive Salivary Gland Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-04-07
Completion: 2021-06-09
Conditions
Salivary Gland Neoplasms
Interventions
DRUG
Results Available
NCT04305431 | RECRUITING | NA
55 Participants

Dietary Behavior Intervention in African Americans at Risk for Cardiovascular Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-02-25
Completion: 2026-12-19
Conditions
Diet Cooking
Interventions
BEHAVIORAL
No Results Yet
NCT04272086 | COMPLETED | PHASE4
140 Participants

Utility of Liposomal Bupivacaine Transversus Abdominal Plane Block for Open Myomectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-11-09
Completion: 2025-10-28
Conditions
Fibroid Uterus
Interventions
DRUG
No Results Yet
NCT04240821 | ENROLLING_BY_INVITATION | PHASE2
34 Participants

Theophylline for Treatment of Pseudohypoparathyroidism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-05-22
Completion: 2026-12-31
Conditions
Pseudohypoparathyroidism Pseudohypoparathyroidism Type 1a Albright Hereditary Osteodystrophy
Interventions
DRUG
No Results Yet
NCT04228367 | RECRUITING | NA
104 Participants

JuggerStitch Post Market Clinical Follow-up Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-09-25
Completion: 2026-03-31
Conditions
Meniscus Tear, Tibial Meniscus Lesion
Interventions
DEVICE
No Results Yet
NCT04221438 | TERMINATED | PHASE2
3 Participants

Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-09-22
Completion: 2024-06-10
Conditions
Melanoma of Unknown Primary Metastatic Malignant Neoplasm in Lymph Node Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 Pathologic Stage IIID Cutaneous Melanoma AJCC v8 Recurrent Cutaneous Melanoma
Interventions
DRUG PROCEDURE OTHER
Results Available
NCT04216290 | ACTIVE_NOT_RECRUITING | PHASE2
95 Participants

A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-03-17
Completion: 2026-06-30
Conditions
Bladder Urothelial Carcinoma Stage III Bladder Cancer AJCC v8
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER RADIATION
No Results Yet
NCT04214067 | ACTIVE_NOT_RECRUITING | PHASE3
168 Participants

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-04-09
Completion: 2025-12-30
Conditions
Endometrial Endometrioid Adenocarcinoma Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 Stage II Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Interventions
PROCEDURE RADIATION BIOLOGICAL OTHER
No Results Yet
NCT04204616 | ACTIVE_NOT_RECRUITING | PHASE3
500 Participants

A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-01-11
Completion: 2026-10-26
Conditions
Prurigo Nodularis
Interventions
DRUG
No Results Yet
NCT04198870 | ACTIVE_NOT_RECRUITING | NA
500 Participants

MitraClip REPAIR MR Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-07-21
Completion: 2027-12-31
Conditions
Mitral Valve Regurgitation
Interventions
DEVICE PROCEDURE
No Results Yet
NCT04196530 | COMPLETED | PHASE1
40 Participants

BDB001-102: Open Label Dose Escalation of BDB001 in Combination w Atezolizumab

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-11-21
Completion: 2024-07-31
Conditions
Tumor, Solid
Interventions
DRUG
No Results Yet
NCT04196374 | COMPLETED | NA
48 Participants

Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-06-09
Completion: 2025-05-30
Conditions
Seemingly Healthy Genetic Predisposition to Disease
Interventions
GENETIC
No Results Yet
NCT04166409 | RECRUITING | PHASE3
170 Participants

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-01-31
Completion: 2030-12-31
Conditions
Low Grade Astrocytoma Low Grade Glioma Metastatic Low Grade Astrocytoma Metastatic Low Grade Glioma WHO Grade 1 Glioma WHO Grade 2 Glioma
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT04150614 | RECRUITING | PHASE4
90 Participants

BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-05-14
Completion: 2026-07-31
Conditions
Nausea With Vomiting Chemotherapy-Induced
Interventions
DRUG
No Results Yet
NCT04145141 | RECRUITING
500 Participants

National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2021-07-28
Completion: 2025-12-31
Conditions
Hepatocellular Carcinoma Liver Cancer Cholangiocarcinoma
No Results Yet
NCT04122976 | ACTIVE_NOT_RECRUITING
805 Participants

A Study in Which Non-metastatic Castration-resistant Prostate Cancer (nmCRPC) Patients for Whom a Decision to Treat With Darolutamide Has Been Made Before Enrollment Are Observed and Certain Outcomes Are Described

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2020-01-30
Completion: 2026-07-07
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT04122196 | COMPLETED | PHASE2/PHASE3
118 Participants

Perioperative Pregabalin in Ureteroscopy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-06-01
Completion: 2023-07-01
Conditions
Kidney Stone Pain, Postoperative Addiction Opioid Use
Interventions
DRUG
Results Available
NCT04115306 | RECRUITING | PHASE1/PHASE2
61 Participants

Phase 1/1b/2 Study of Oral PMD-026 in Patients With Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-11-14
Completion: 2026-09-30
Conditions
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT04102371 | ACTIVE_NOT_RECRUITING | PHASE3
8800 Participants

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-08-25
Completion: 2026-01-31
Conditions
Shock Septic
Interventions
DRUG
No Results Yet
NCT04083976 | ACTIVE_NOT_RECRUITING | PHASE2
316 Participants

A Study of Erdafitinib in Participants With Advanced Solid Tumors and Fibroblast Growth Factor Receptor (FGFR) Gene Alterations

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-11-20
Completion: 2023-12-04
Conditions
Advanced Solid Tumor
Interventions
DRUG
Results Available
NCT04074512 | AVAILABLE

Copper Histidinate Treatment for Menkes Disease

Study Type: EXPANDED_ACCESS
Last Updated: 2025-11-12
Conditions
Menkes Disease
Interventions
DRUG
No Results Yet
NCT04064060 | RECRUITING | PHASE3
665 Participants

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-08-12
Completion: 2028-05-12
Conditions
Myelodysplastic Syndromes (MDS) Beta-thalassemia Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis
Interventions
DRUG
No Results Yet
NCT04033445 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
1064 Participants

A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-09-26
Completion: 2023-09-19
Conditions
Ulcerative Colitis
Interventions
DRUG
Results Available
NCT04026386 | RECRUITING | NA
75 Participants

A Center Based Early Intervention Program For Preschoolers With Developmental Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-10-19
Completion: 2034-12-30
Conditions
Development Disorder, Child Developmental Disability Development Delay Autism Spectrum Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT04008797 | RECRUITING | PHASE1/PHASE2
301 Participants

A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-07-11
Completion: 2027-08-31
Conditions
Endometrial Neoplasms Neoplasms Carcinoma, Hepatocellular Liver Neoplasms Colorectal Neoplasms
Interventions
DRUG
No Results Yet
NCT04008368 | RECRUITING | PHASE1/PHASE2
32 Participants

Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-10-24
Completion: 2030-01-30
Conditions
Myeloid Chimerism
Interventions
DEVICE
No Results Yet
NCT04001829 | ACTIVE_NOT_RECRUITING | PHASE2
249 Participants

Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-08-09
Completion: 2023-09-19
Conditions
Anatomic Stage I Breast Cancer AJCC v8 Anatomic Stage IA Breast Cancer AJCC v8 Anatomic Stage IB Breast Cancer AJCC v8 Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage IIA Breast Cancer AJCC v8 Anatomic Stage IIB Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IIIA Breast Cancer AJCC v8 Anatomic Stage IIIB Breast Cancer AJCC v8 Anatomic Stage IIIC Breast Cancer AJCC v8 Invasive Breast Carcinoma Prognostic Stage I Breast Cancer AJCC v8 Prognostic Stage IA Breast Cancer AJCC v8 Prognostic Stage IB Breast Cancer AJCC v8 Prognostic Stage II Breast Cancer AJCC v8 Prognostic Stage IIA Breast Cancer AJCC v8 Prognostic Stage IIB Breast Cancer AJCC v8 Prognostic Stage III Breast Cancer AJCC v8 Prognostic Stage IIIA Breast Cancer AJCC v8 Prognostic Stage IIIB Breast Cancer AJCC v8 Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions
DRUG OTHER
Results Available
NCT03987386 | ACTIVE_NOT_RECRUITING | PHASE3
186 Participants

Conventional or Hypofractionated Radiation Therapy in Treating Patients With Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-05-30
Completion: 2027-11-01
Conditions
Stage I Prostate Cancer AJCC v8 Stage II Prostate Cancer AJCC v8 Stage III Prostate Cancer AJCC v8 Stage IVA Prostate Cancer AJCC v8
Interventions
RADIATION OTHER
No Results Yet
NCT03986021 | RECRUITING
400 Participants

Reproductive Axis Maturation in the Early Post-Menarchal Years

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2019-12-19
Completion: 2029-07-01
Conditions
Reproductive Physiological Processes Pediatrics Adolescent Health Adolescent Development
No Results Yet
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