Clinical Trials

NCT04657146 | SUSPENDED
40 Participants

Longitudinal Assessment of Marrow and Blood in Patients With Glioblastoma

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-05
Completion: 2027-11-01
Conditions
Glioblastoma
Interventions
OTHER
No Results Yet
NCT04649242 | RECRUITING | PHASE3
2100 Participants

Randomized Study in Children and Adolescents With Migraine: Acute Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-01-15
Completion: 2029-01-09
Conditions
Pediatric Migraine
Interventions
DRUG
No Results Yet
NCT04647487 | COMPLETED | PHASE1
87 Participants

A Study of LY3484356 in Women With Breast Cancer Before Having Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-04-21
Completion: 2022-11-11
Conditions
Breast Cancer
Interventions
DRUG
NCT04628767 | RECRUITING | PHASE2/PHASE3
249 Participants

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-11-12
Completion: 2027-09-30
Conditions
Renal Pelvis and Ureter Urothelial Carcinoma
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT04628494 | ACTIVE_NOT_RECRUITING | PHASE3
484 Participants

A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-01-13
Completion: 2025-10-13
Conditions
Diffuse Large B-cell Lymphoma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT04622332 | COMPLETED | PHASE1
45 Participants

A Pilot Study to Assess Safety and Efficacy of SIR1-365 in Patients With Severe COVID-19

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-12-18
Completion: 2021-11-27
Conditions
Corona Virus Infection
Interventions
DRUG
NCT04614103 | RECRUITING | PHASE2
170 Participants

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-05-07
Completion: 2030-12-31
Conditions
Metastatic Non Small Cell Lung Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT04613596 | RECRUITING | PHASE2/PHASE3
806 Participants

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-12-02
Completion: 2028-10-31
Conditions
Advanced Non-Small Cell Lung Cancer Metastatic Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT04606095 | RECRUITING | NA
150 Participants

Explosive Synchronization of Brain Network Activity in Chronic Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-11-13
Completion: 2026-02-20
Conditions
Fibromyalgia Healthy Volunteers
Interventions
DIAGNOSTIC_TEST DEVICE
No Results Yet
NCT04561518 | RECRUITING
1500 Participants

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2020-11-23
Completion: 2030-09-01
Conditions
Transthyretin-Mediated Amyloidosis ATTR Amyloidosis
No Results Yet
NCT04551430 | ACTIVE_NOT_RECRUITING | PHASE2
105 Participants

Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-01-05
Completion: 2027-02-01
Conditions
Metastatic Soft-tissue Sarcoma
Interventions
DRUG
No Results Yet
NCT04551170 | ACTIVE_NOT_RECRUITING | PHASE2
34 Participants

Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-07-13
Completion: 2026-12-31
Conditions
Pseudohypoparathyroidism Albright Hereditary Osteodystrophy Pseudohypoparathyroidism Type 1a
Interventions
DRUG
No Results Yet
NCT04543591 | ACTIVE_NOT_RECRUITING | PHASE3
148 Participants

Ravulizumab in Thrombotic Microangiopathy After Hematopoietic Stem Cell Transplant

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-12-10
Completion: 2025-09-19
Conditions
Thrombotic Microangiopathy
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT04527549 | TERMINATED | PHASE2
5 Participants

Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-06-01
Completion: 2024-01-08
Conditions
Clinical Stage IV Cutaneous Melanoma AJCC v8 Locally Advanced Melanoma Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 Pathologic Stage IV Cutaneous Melanoma AJCC v8 Unresectable Melanoma
Interventions
DRUG
NCT04518228 | COMPLETED
205 Participants

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2021-09-01
Completion: 2025-04-24
Conditions
HIV Infections Tuberculosis
Interventions
DRUG
No Results Yet
NCT04514861 | ACTIVE_NOT_RECRUITING | NA
53 Participants

Monitoring Local Tissue Oxygen Changes Using the Wireless Lumee Oxygen Platform in Correlation to TcPO2

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-12-18
Completion: 2027-03-30
Conditions
Peripheral Artery Disease
Interventions
DEVICE
No Results Yet
NCT04477512 | COMPLETED | PHASE1
18 Participants

Cabozantinib and Abiraterone With Checkpoint Inhibitor Immunotherapy in Metastatic Hormone Sensitive Prostate Cancer (CABIOS Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-02-19
Completion: 2021-09-09
Conditions
Metastatic Hormone Refractory Prostate Cancer
Interventions
DRUG PROCEDURE
No Results Yet
NCT04465214 | COMPLETED
49 Participants

Mobile Sensor Technologies to Assess General Symptomology of People With Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2020-11-23
Completion: 2024-04-10
Conditions
Neoplasms Solid Tumors Prostate Cancer Lung Cancer Colon Cancer
No Results Yet
NCT04440228 | COMPLETED | NA
90 Participants

TeamSTEPPS in School Mental Health

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2022-05-23
Completion: 2024-04-30
Conditions
Child Behavior Problem Multidisciplinary Communication Interprofessional Relations
Interventions
BEHAVIORAL
NCT04415515 | TERMINATED | NA
592023 Participants

Standard Care Coordination Expansion Pilot

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2015-10-31
Completion: 2023-12-31
Conditions
Superutilizers, Health Care Utilization
Interventions
BEHAVIORAL
No Results Yet
NCT04384172 | COMPLETED | NA
9 Participants

Effect of Peripheral Neuromodulation on Vaginal Blood Flow

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-11-11
Completion: 2022-03-15
Conditions
Female Sexual Dysfunction Spinal Cord Injuries
Interventions
DEVICE
NCT04375072 | COMPLETED | NA
208 Participants

Home-based tDCS and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-08-13
Completion: 2025-01-30
Conditions
Osteo Arthritis Knee
Interventions
DEVICE
NCT04353492 | COMPLETED | PHASE3
562 Participants

An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-07-14
Completion: 2024-10-09
Conditions
Relapsing Multiple Sclerosis
Interventions
BIOLOGICAL
NCT04349059 | RECRUITING | NA
46 Participants

The Impact of Dietary Pattern on Erectile Function

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-10-30
Completion: 2026-12-31
Conditions
Erectile Dysfunction
Interventions
OTHER
No Results Yet
NCT04325828 | ACTIVE_NOT_RECRUITING | PHASE2
31 Participants

A Study of Apalutamide Combined With GnRH Agonist in Participants With Androgen Receptor Positive Salivary Gland Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-04-07
Completion: 2021-06-09
Conditions
Salivary Gland Neoplasms
Interventions
DRUG
NCT04305431 | RECRUITING | NA
55 Participants

Dietary Behavior Intervention in African Americans at Risk for Cardiovascular Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-02-25
Completion: 2026-12-19
Conditions
Diet Cooking
Interventions
BEHAVIORAL
No Results Yet
NCT04272086 | COMPLETED | PHASE4
140 Participants

Utility of Liposomal Bupivacaine Transversus Abdominal Plane Block for Open Myomectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-11-09
Completion: 2025-10-28
Conditions
Fibroid Uterus
Interventions
DRUG
No Results Yet
NCT04240821 | ENROLLING_BY_INVITATION | PHASE2
34 Participants

Theophylline for Treatment of Pseudohypoparathyroidism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-05-22
Completion: 2026-12-31
Conditions
Pseudohypoparathyroidism Pseudohypoparathyroidism Type 1a Albright Hereditary Osteodystrophy
Interventions
DRUG
No Results Yet
NCT04228367 | RECRUITING | NA
104 Participants

JuggerStitch Post Market Clinical Follow-up Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-09-25
Completion: 2026-03-31
Conditions
Meniscus Tear, Tibial Meniscus Lesion
Interventions
DEVICE
No Results Yet
NCT04221438 | TERMINATED | PHASE2
3 Participants

Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-09-22
Completion: 2024-06-10
Conditions
Melanoma of Unknown Primary Metastatic Malignant Neoplasm in Lymph Node Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 Pathologic Stage IIID Cutaneous Melanoma AJCC v8 Recurrent Cutaneous Melanoma
Interventions
DRUG PROCEDURE OTHER
NCT04216290 | ACTIVE_NOT_RECRUITING | PHASE2
95 Participants

A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-03-17
Completion: 2026-06-30
Conditions
Bladder Urothelial Carcinoma Stage III Bladder Cancer AJCC v8
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER RADIATION
No Results Yet
NCT04214067 | ACTIVE_NOT_RECRUITING | PHASE3
168 Participants

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-04-09
Completion: 2025-12-30
Conditions
Endometrial Endometrioid Adenocarcinoma Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 Stage II Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Interventions
PROCEDURE RADIATION BIOLOGICAL OTHER
No Results Yet
NCT04204616 | ACTIVE_NOT_RECRUITING | PHASE3
500 Participants

A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-01-11
Completion: 2026-10-26
Conditions
Prurigo Nodularis
Interventions
DRUG
No Results Yet
NCT04198870 | ACTIVE_NOT_RECRUITING | NA
500 Participants

MitraClip REPAIR MR Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-07-21
Completion: 2027-12-31
Conditions
Mitral Valve Regurgitation
Interventions
DEVICE PROCEDURE
No Results Yet
NCT04196530 | COMPLETED | PHASE1
40 Participants

BDB001-102: Open Label Dose Escalation of BDB001 in Combination w Atezolizumab

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-11-21
Completion: 2024-07-31
Conditions
Tumor, Solid
Interventions
DRUG
No Results Yet
NCT04196374 | COMPLETED | NA
48 Participants

Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-06-09
Completion: 2025-05-30
Conditions
Seemingly Healthy Genetic Predisposition to Disease
Interventions
GENETIC
No Results Yet
NCT04166409 | RECRUITING | PHASE3
170 Participants

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-01-31
Completion: 2030-12-31
Conditions
Low Grade Astrocytoma Low Grade Glioma Metastatic Low Grade Astrocytoma Metastatic Low Grade Glioma WHO Grade 1 Glioma WHO Grade 2 Glioma
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT04150614 | RECRUITING | PHASE4
90 Participants

BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-05-14
Completion: 2026-07-31
Conditions
Nausea With Vomiting Chemotherapy-Induced
Interventions
DRUG
No Results Yet
NCT04145141 | RECRUITING
500 Participants

National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2021-07-28
Completion: 2025-12-31
Conditions
Hepatocellular Carcinoma Liver Cancer Cholangiocarcinoma
No Results Yet
NCT04122976 | ACTIVE_NOT_RECRUITING
805 Participants

A Study in Which Non-metastatic Castration-resistant Prostate Cancer (nmCRPC) Patients for Whom a Decision to Treat With Darolutamide Has Been Made Before Enrollment Are Observed and Certain Outcomes Are Described

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2020-01-30
Completion: 2026-07-07
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
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