Clinical Trials
165
Participants
A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2017-10-24
Completion:
2024-08-28
Conditions
Pulmonary Arterial Hypertension
Interventions
DRUG
OTHER
5
Participants
Deep Brain Stimulation Surgery for Focal Hand Dystonia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-01-17
Completion:
2029-02-02
Conditions
Dystonia
Focal Dystonia
Musician's Dystonia
Interventions
PROCEDURE
DEVICE
No Results Yet
26
Participants
Trial of CUDC-907 in Children and Young Adults With Relapsed or Refractory Solid Tumors, CNS Tumors, or Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2016-10-31
Completion:
2026-01-31
Conditions
Lymphoma
Neuroblastoma
Brain Tumor
Solid Tumor
Interventions
DRUG
No Results Yet
289
Participants
An Efficacy and Safety Study of Niraparib in Men With Metastatic Castration-Resistant Prostate Cancer and DNA-Repair Anomalies
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2016-08-31
Completion:
2021-01-26
Conditions
Prostatic Neoplasms
Interventions
DRUG
18
Participants
Nivolumab in Combination With Plinabulin in Patients With Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2016-08-29
Completion:
2024-11-24
Conditions
Non-small Cell Lung Cancer Metastatic
Interventions
DRUG
No Results Yet
160
Participants
A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2016-06-22
Completion:
2026-08-31
Conditions
Craniopharyngioma
Interventions
RADIATION
PROCEDURE
No Results Yet
33
Participants
DNA Vaccine Therapy in Treating Patients With Chronic Hepatitis C Virus Infection
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2016-06-06
Completion:
2020-03-04
Conditions
Chronic Hepatitis
Hepatitis C Infection
Hepatocellular Carcinoma
Interventions
BIOLOGICAL
OTHER
No Results Yet
156
Participants
PROMOTE: Identifying Predictive Markers of Response for Genitourinary Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2016-05-25
Completion:
2027-03-31
Conditions
Prostate Cancer
Advanced Renal Cell Carcinoma
Advanced Urothelial Carcinoma
Genitourinary Cancer
Interventions
OTHER
DEVICE
No Results Yet
58
Participants
Autoimmune Basis for Postural Tachycardia Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2016-02-29
Completion:
2026-10-31
Conditions
Postural Orthostatic Tachycardia Syndrome
Postural Tachycardia Syndrome
Tachycardia
Arrhythmias, Cardiac
Autonomic Nervous System Diseases
Orthostatic Intolerance
Cardiovascular Diseases
Primary Dysautonomias
Interventions
DRUG
RADIATION
PROCEDURE
OTHER
No Results Yet
677
Participants
Fluorescent Cholangiography vs White Light for Bile Ducts Identification
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2016-04-30
Completion:
2017-12-31
Conditions
Cholecystitis
Cholelithiasis
Interventions
PROCEDURE
308
Participants
Optimal Treatment for Recurrent Clostridium Difficile
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2015-12-21
Completion:
2024-08-07
Conditions
Clostridium
Difficile
Fidaxomicin
Vancomycin
Interventions
DRUG
150
Participants
Evaluation of Three Pulp Vitality Tests
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2026-01-31
Completion:
2027-12-31
Conditions
Dental Pulp Diseases
Dental Pulp Vitality Testing
Interventions
DEVICE
No Results Yet
0
Participants
Ultrasound vs Veinviewer in Patients With Difficulty IV Access
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2016-08-01
Completion:
2025-05-05
Conditions
Vascular Access Complication
Interventions
DEVICE
No Results Yet
332
Participants
A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2015-11-30
Completion:
2025-11-30
Conditions
Progressive Supranuclear Palsy
Interventions
DRUG
No Results Yet
215
Participants
A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2015-09-30
Completion:
2025-09-29
Conditions
Solid Tumors Harboring NTRK Fusion
Interventions
DRUG
No Results Yet
10000
Participants
Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2015-09-17
Completion:
2040-06-04
Conditions
Undiagnosed Diseases
Cardiovascular Disease
No Results Yet
340
Participants
Study to Assess MEDI4736 With Either AZD9150 or AZD5069 in Advanced Solid Tumors & Relapsed Metastatic Squamous Cell Carcinoma of Head & Neck
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2015-08-06
Completion:
2020-02-28
Conditions
Advanced Solid Tumors & Metastatic Squamous Cell Carcinoma of the Head and Neck
Interventions
DRUG
268
Participants
Phase I/II Study of the Anti-Programmed Death Ligand-1 Durvalumab Antibody (MEDI4736) in Combination With Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal Can...
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2015-06-29
Completion:
2026-04-01
Conditions
Colorectal Neoplasms
Breast Neoplasms
Interventions
DRUG
No Results Yet
200
Participants
Compassionate Access of the Miltenyi Device for CD34+ Cell Selection
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2015-05-06
Completion:
2027-05-01
Conditions
Blood And Marrow Transplantation
Interventions
BIOLOGICAL
DEVICE
No Results Yet
49331
Participants
Women's Health Initiative Strong and Healthy Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2015-04-02
Completion:
2024-12-31
Conditions
Myocardial Infarction
Stroke
Cardiovascular Mortality
Hip Fractures
Falls
Mortality
Venous Thromboembolic Event
Peripheral Artery Disease
Physical Function
Coronary Revascularization
Mobility and Independence
Clinical (Non-hip) Fractures
Sleep
Depressive Symptoms
Interventions
BEHAVIORAL
No Results Yet
100
Participants
Relationship Between Endoscopic Ultrasound Staging and Degree of Stricture in Esophageal Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2012-04-30
Completion:
2014-04-30
Conditions
Esophageal Cancer
Interventions
PROCEDURE
No Results Yet
239
Participants
An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2015-04-22
Completion:
2022-09-15
Conditions
Urothelial Cancer
Interventions
DRUG
24
Participants
Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2014-10-09
Completion:
2027-07-31
Conditions
Lipodystrophy
Diabetes
Hyperlipidemia
Interventions
DRUG
No Results Yet
29
Participants
Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2014-10-14
Completion:
2027-07-31
Conditions
Diabetes
Lipodystrophy
Hyperlipidemia
Interventions
DRUG
No Results Yet
982
Participants
An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2014-11-26
Completion:
2018-03-19
Conditions
Prostatic Neoplasms
Interventions
DRUG
70
Participants
HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2014-04-30
Completion:
2026-12-31
Conditions
Fanconi Anemia
Severe Marrow Failure
Myelodysplastic Syndrome (MDS)
Acute Myelogenous Leukemia (AML)
Interventions
DRUG
BIOLOGICAL
No Results Yet
300
Participants
Deep Brain Stimulation Therapy in Movement Disorders
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2014-04-02
Completion:
2030-12-01
Conditions
Parkinson's Disease
Interventions
DEVICE
No Results Yet
50
Participants
Modulation of Molecular Fingerprinting in Pediatric Sepsis
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2014-03-31
Completion:
2027-06-30
Conditions
Systemic Inflammatory Response Syndrome
Interventions
PROCEDURE
No Results Yet
300
Participants
MR Imaging of Perinatal Brain Injury
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2009-07-01
Completion:
2028-12-31
Conditions
Perinatal White Matter Brain Injury
Interventions
DEVICE
BEHAVIORAL
No Results Yet
1207
Participants
A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2013-10-14
Completion:
2017-05-19
Conditions
Prostatic Neoplasms
Interventions
DRUG
83
Participants
Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2013-05-31
Completion:
2027-05-31
Conditions
Newly Diagnosed Ewing Sarcoma
Interventions
DRUG
DEVICE
PROCEDURE
RADIATION
No Results Yet
44
Participants
Ibrutinib in Treating Patients With Relapsed Hairy Cell Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2013-04-30
Completion:
2029-12-31
Conditions
Hairy Cell Leukemia
Hairy Cell Leukemia Variant
Recurrent Hairy Cell Leukemia
Recurrent Hairy Cell Leukemia Variant
Interventions
PROCEDURE
DRUG
No Results Yet
50
Participants
Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-07-01
Completion:
2028-06-30
Conditions
PPA
Non-fluent Aphasia
Apraxia of Speech
Primary Progressive Non-fluent Aphasia
Primary Progressive Aphasia
Interventions
DRUG
No Results Yet
490
Participants
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2012-12-31
Completion:
2028-04-30
Conditions
Alzheimers Disease
Dementia
Alzheimers Disease, Familial
Interventions
DRUG
No Results Yet
0
Participants
Surveying Parents About Genome Screening of Newborns
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Conditions
Parents of Healthy Newborns
Interventions
OTHER
No Results Yet
4800
Participants
RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2012-11-19
Completion:
2035-05-31
Conditions
Pain
Interventions
DEVICE
No Results Yet
70
Participants
Spironolactone for Pulmonary Arterial Hypertension
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2014-01-10
Completion:
2026-12-31
Conditions
Pulmonary Arterial Hypertension
Interventions
DRUG
No Results Yet
178
Participants
Decitabine, Cytarabine, and Daunorubicin Hydrochloride in Treating Patients With Acute Myeloid Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2011-09-16
Completion:
2016-02-11
Conditions
Acute Myeloid Leukemia
Adult Acute Basophilic Leukemia
Adult Acute Monoblastic Leukemia
Adult Acute Monocytic Leukemia
Adult Acute Myeloid Leukemia With Maturation
Adult Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3); MLLT3-KMT2A
Adult Acute Myeloid Leukemia Without Maturation
Adult Acute Myelomonocytic Leukemia
Alkylating Agent-Related Acute Myeloid Leukemia
Secondary Acute Myeloid Leukemia
Interventions
DRUG
OTHER
No Results Yet
360
Participants
Promoting Breast Cancer Screening in Women Who Survived Childhood Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2010-07-31
Completion:
2026-07-31
Conditions
Cancer
Interventions
BEHAVIORAL
No Results Yet
131
Participants
IMAAGEN: Impact of Abiraterone Acetate in Prostate-Specific Antigen
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2011-05-04
Completion:
2013-12-24
Conditions
Prostate Cancer
Prostatic Neoplasm
Interventions
DRUG
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