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Clinical Trials

NCT06922604 | RECRUITING | PHASE1
20 Participants

Glofitamab With Obinutuzumab Pre-treatment for the Treatment of Central Nervous System Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-30
Completion: 2029-01-02
Conditions
Primary Central Nervous System Lymphoma Secondary Central Nervous System Lymphoma
Interventions
PROCEDURE BIOLOGICAL
No Results Yet
NCT06919965 | RECRUITING | PHASE3
220 Participants

A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-09-10
Completion: 2028-04-06
Conditions
Non-Muscle Invasive Bladder Neoplasms
Interventions
DRUG
No Results Yet
NCT06919471 | RECRUITING | NA
90 Participants

Assessing User Satisfaction and Adherence to an Abbreviated Dietary Tracking App (MySnackTracker) Versus Full-intake Dietary Monitoring

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-08
Completion: 2028-05-01
Conditions
Dietary Monitoring
Interventions
OTHER
No Results Yet
NCT06916767 | RECRUITING | PHASE1
18 Participants

Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-15
Completion: 2027-12-31
Conditions
Relapsed CLL Refractory CLL Refractory Lymphoma
Interventions
DRUG
No Results Yet
NCT06915025 | RECRUITING | PHASE3
500 Participants

Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-09
Completion: 2032-10-31
Conditions
Epithelial Ovarian Cancer Ovarian Cancer Fallopian Tube Cancer Primary Peritoneal Carcinoma
Interventions
DRUG
No Results Yet
NCT06914128 | RECRUITING | PHASE1/PHASE2
370 Participants

A First-in-human Study to Learn How Safe BAY 3713372 is and How it Works in Participants With MTAP-deleted Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-21
Completion: 2029-06-17
Conditions
MTAP-deleted Solid Tumors
Interventions
DRUG
No Results Yet
NCT06911008 | RECRUITING | PHASE1
42 Participants

MTI-301 for the Treatment of Metastatic or Unresectable and Refractory Solid Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-07
Completion: 2027-04-09
Conditions
Metastatic Malignant Solid Neoplasm Refractory Malignant Solid Neoplasm Unresectable Malignant Solid Neoplasm
Interventions
PROCEDURE OTHER BIOLOGICAL
No Results Yet
NCT06910813 | RECRUITING | PHASE1/PHASE2
30 Participants

DFT383 in Pediatric Participants With Nephropathic Cystinosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-02
Completion: 2031-03-14
Conditions
Nephropathic Cystinosis
Interventions
GENETIC
No Results Yet
NCT06910761 | RECRUITING | PHASE2
35 Participants

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-05
Completion: 2028-10-02
Conditions
Anatomic Stage IV Breast Cancer AJCC v8 Metastatic Breast Carcinoma Metastatic Lung Non-Small Cell Carcinoma Metastatic Malignant Neoplasm in the Leptomeninges Stage IV Lung Cancer AJCC v8
Interventions
PROCEDURE RADIATION OTHER
No Results Yet
NCT06907979 | NOT_YET_RECRUITING | NA
24 Participants

Cannabis and Processing Emotions Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-31
Completion: 2027-05-31
Conditions
Cannabis Use Disorder, Severe
Interventions
DEVICE
No Results Yet
NCT06907875 | RECRUITING | PHASE1/PHASE2
9 Participants

A First-in-human Study of EPI-321 in Facioscapulohumeral Muscular Dystrophy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-08
Completion: 2031-03-31
Conditions
Facioscapulohumeral Muscular Dystrophy
Interventions
BIOLOGICAL
No Results Yet
NCT06906926 | RECRUITING | NA
80 Participants

Harmony TPV EMEA PMS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-30
Completion: 2027-07-31
Conditions
Severe Pulmonary Valve Regurgitation
Interventions
RADIATION
No Results Yet
NCT06903897 | RECRUITING | NA
68000 Participants

Social Needs Screening and Chronic Diseases Study (WE CARE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-08
Completion: 2028-09-30
Conditions
Hyperlipidemias Diabetes Depression Pediatric Asthma Hypertension
Interventions
OTHER
No Results Yet
NCT06902480 | NOT_YET_RECRUITING | NA
24 Participants

Dairy Choline Bioavailability

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-30
Completion: 2026-08-31
Conditions
Post-menopausal Women Post-menopausal Status
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06895681 | NOT_YET_RECRUITING
50000 Participants

UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-31
Completion: 2035-12-31
Conditions
Solid Tumor Solid Tumor, Adult Somatic Mutation Solid Tumor, Unspecified, Adult Hereditary Cancer
Interventions
PROCEDURE OTHER
No Results Yet
NCT06892522 | RECRUITING | PHASE1/PHASE2
440 Participants

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion Alone or in Combination With Oral, IV, Subcutaneous Daratumumab; Lenalidomide; Dexamethasone; Carfilzomib

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-30
Completion: 2036-02-29
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06883305 | RECRUITING | PHASE3
990 Participants

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-18
Completion: 2029-03-13
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06878404 | RECRUITING | PHASE3
540 Participants

A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naรฏve Participants With Active Psoriatic Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-21
Completion: 2026-05-27
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
NCT06878261 | RECRUITING | PHASE3
990 Participants

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-25
Completion: 2029-03-13
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06878131 | RECRUITING
40 Participants

Precision-MRD: Prospective Observational Study of Biomarker-directed Systemic Therapy for Colorectal Cancer Patients With Minimal Residual Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-18
Completion: 2026-12-22
Conditions
Colorectal Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06877676 | APPROVED_FOR_MARKETING

Pre-Approval Expanded Access Study for TAR-200 Treating Physician Use

Study Type: EXPANDED_ACCESS
Last Updated: 2025-11-10
Conditions
Non-Muscle Invasive Bladder Neoplasms
Interventions
DRUG
No Results Yet
NCT06876259 | NOT_YET_RECRUITING | NA
300 Participants

Artificial Intelligence Diagnostic Decision Support to Reduce Antimicrobial Prescriptions in Young Children With Colds

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-30
Completion: 2026-11-30
Conditions
Acute Otitis Media (AOM) Upper Respiratory Infection
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06871579 | RECRUITING | NA
25 Participants

Study of the Esophageal String Test (EST) for the Diagnosis of Helicobacter Pylori

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-11
Completion: 2026-01-30
Conditions
Helicobacter Pylori
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06870812 | RECRUITING | NA
600 Participants

Rapid Evacuation and Access of Cerebral Hemorrhage Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-27
Completion: 2030-03-31
Conditions
Stroke Hemorrhagic
Interventions
PROCEDURE OTHER
No Results Yet
NCT06866288 | COMPLETED | NA
32 Participants

Belongingness in Nursing Through Mindfulness - BEING Mindful: A Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-29
Completion: 2025-10-14
Conditions
Mindfulness Sense of Belonging
Interventions
BEHAVIORAL
No Results Yet
NCT06866106 | RECRUITING | NA
50 Participants

Well-being in IBS: Strengths and Happiness (WISH) 2.0

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-30
Completion: 2028-04-30
Conditions
Irritable Bowel Syndrome
Interventions
BEHAVIORAL
No Results Yet
NCT06864858 | COMPLETED | NA
53 Participants

Clinical Evaluation of Two Cosmetic Contact Lenses

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-30
Completion: 2025-05-05
Conditions
Visual Acuity
Interventions
DEVICE
No Results Yet
NCT06863961 | RECRUITING | PHASE2
160 Participants

A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-01
Completion: 2026-07-13
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
NCT06863129 | RECRUITING | NA
334 Participants

Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-01
Completion: 2029-06-01
Conditions
Metastatic Bone Disease
Interventions
PROCEDURE
No Results Yet
NCT06860594 | RECRUITING | PHASE1
30 Participants

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-30
Completion: 2027-06-30
Conditions
Astrocytoma, IDH-Mutant, Grade 2 Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-Mutant Recurrent Adult Diffuse Midline Glioma, H3 K27-Mutant Recurrent Astrocytoma, IDH-Mutant Recurrent Astrocytoma, IDH-Mutant, Grade 3 Recurrent Astrocytoma, IDH-Mutant, Grade 4 Recurrent Glioblastoma, IDH-Wildtype
Interventions
PROCEDURE RADIATION DRUG
No Results Yet
NCT06858813 | RECRUITING | PHASE1
232 Participants

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-14
Completion: 2030-09-30
Conditions
Hepatocellular Cancer Squamous-Cell Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06855498 | RECRUITING | PHASE3
600 Participants

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-28
Completion: 2028-02-28
Conditions
Hidradenitis Suppurativa (HS)
Interventions
DRUG
No Results Yet
NCT06852222 | RECRUITING | PHASE3
600 Participants

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-04
Completion: 2029-06-22
Conditions
Leukemia, Myeloid, Acute
Interventions
DRUG
No Results Yet
NCT06850922 | RECRUITING | PHASE1/PHASE2
546 Participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603 Administered Alone or in Combination With Aflibercept or Faricimab in Participants With Diabetic Macular Edema

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-06-22
Completion: 2027-04-30
Conditions
Diabetic Macular Edema
Interventions
DRUG
No Results Yet
NCT06845358 | NOT_YET_RECRUITING | PHASE1
64 Participants

Safety and Challenge Study of BCG TICE(R) Vaccination to Test Tuberculosis Immunity in Heathy Humans

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-28
Completion: 2026-09-01
Conditions
Tuberculosis
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06843239 | RECRUITING | PHASE2
80 Participants

Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-06
Completion: 2026-12-31
Conditions
Systemic Sclerosis (SSc) Scleroderma
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06841354 | RECRUITING | PHASE3
1000 Participants

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-16
Completion: 2030-05-18
Conditions
Triple Negative Breast Neoplasms
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06834347 | RECRUITING | PHASE3
210 Participants

A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-12
Completion: 2027-01-08
Conditions
Chronic Rhinosinusitis With Nasal Polyps
Interventions
DRUG
No Results Yet
NCT06833294 | RECRUITING
48 Participants

GentleFit Non-Invasive Ventilation (NIV) Interface Trial

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-24
Completion: 2026-10-30
Conditions
Device Ineffective Device Induced Injury
Interventions
DEVICE
No Results Yet
NCT06832618 | RECRUITING | PHASE3
240 Participants

A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-17
Completion: 2026-07-13
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
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