Clinical Trials

NCT06830798 | RECRUITING | PHASE3
450 Participants

Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-19
Completion: 2028-01-28
Conditions
Delayed Graft Function DGF Kidney Transplant
Interventions
DRUG
No Results Yet
NCT06824181 | RECRUITING | PHASE3
580 Participants

Study of Mixed Vaccination Schedules With a 21-valent Pneumococcal Conjugate Vaccine and a 20-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-27
Completion: 2027-08-26
Conditions
Pneumococcal Immunization
Interventions
BIOLOGICAL
No Results Yet
NCT06822426 | RECRUITING | PHASE3
200 Participants

Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-14
Completion: 2027-01-31
Conditions
Central Line Associated Blood Stream Infections (CLABSI)
Interventions
DRUG
No Results Yet
NCT06822374 | WITHDRAWN | PHASE2/PHASE3
0 Participants

Hypertonic Saline in Posterior Spinal Fusion

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-31
Completion: 2028-05-31
Conditions
Scoliosis Idiopathic Scoliosis;Congenital
Interventions
DRUG
No Results Yet
NCT06821997 | RECRUITING | PHASE2
20 Participants

NALIRIFOX Before Surgery for the Treatment of Borderline Resectable Pancreatic Ductal Adenocarcinoma, Nectar Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-01
Completion: 2027-03-01
Conditions
Borderline Resectable Pancreatic Ductal Adenocarcinoma
Interventions
PROCEDURE DRUG
No Results Yet
NCT06817382 | RECRUITING | PHASE1
12 Participants

A Study to Investigate the Safety and Biodistribution of a Single Intrathecal (IT) Injection of INS1201 in Ambulatory Males With Duchenne Muscular Dystrophy (DMD)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-22
Completion: 2028-01-31
Conditions
Duchenne Muscular Dystrophy
Interventions
GENETIC
No Results Yet
NCT06813014 | NOT_YET_RECRUITING | PHASE4
400 Participants

Pharmacogenetics of Response to Sitagliptin (PRS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-31
Completion: 2031-12-31
Conditions
Diabetes
Interventions
PROCEDURE
No Results Yet
NCT06810505 | RECRUITING | PHASE3
420 Participants

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-13
Completion: 2031-03-31
Conditions
Chronic Migraine
Interventions
DRUG
No Results Yet
NCT06809595 | RECRUITING | PHASE3
250 Participants

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-29
Completion: 2026-11-30
Conditions
Generalized Anxiety Disorder
Interventions
OTHER DRUG
No Results Yet
NCT06808984 | RECRUITING | PHASE2
120 Participants

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-09
Completion: 2027-07-27
Conditions
Agitation Alzheimer Disease
Interventions
DRUG
No Results Yet
NCT06807463 | RECRUITING | PHASE2
48 Participants

A Trial to Assess the Efficacy and Safety of TEV-53408 in Adults With Celiac Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-31
Completion: 2026-09-15
Conditions
Celiac Disease
Interventions
DRUG
No Results Yet
NCT06807424 | RECRUITING | PHASE3
750 Participants

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced Participants With Active Psoriatic Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-09
Completion: 2027-02-10
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
NCT06794996 | RECRUITING | PHASE2
45 Participants

Inaxaplin in Participants With Proteinuric APOL1 Mediated Kidney Disease With or Without Comorbidities

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-04
Completion: 2026-12-30
Conditions
Proteinuric Kidney Disease
Interventions
DRUG
No Results Yet
NCT06792695 | RECRUITING | PHASE2
120 Participants

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-12
Completion: 2027-05-31
Conditions
Metastatic Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT06792552 | RECRUITING | PHASE1
414 Participants

A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-26
Completion: 2028-02-29
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06790693 | RECRUITING | PHASE3
450 Participants
NCT06788990 | RECRUITING | PHASE2/PHASE3
650 Participants

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-28
Completion: 2028-04-30
Conditions
Metastatic Head and Neck Squamous Cell Carcinoma Recurrent Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT06788522 | NOT_YET_RECRUITING | PHASE4
40120 Participants

The Effects of Orexin Antagonism on Fear Extinction in PTSD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-01
Completion: 2032-03-01
Conditions
Insomnia PTSD
Interventions
DRUG
No Results Yet
NCT06786572 | RECRUITING | NA
48 Participants

Interoceptive Training Enhanced Mindfulness

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-09-10
Completion: 2027-03-31
Conditions
Anxiety Sensitivity
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT06786494 | COMPLETED | NA
20 Participants

Tart Cherry Juice for Sleep in Older Adults With Insomnia: A Pilot Study of Feasibility and Comprehensive Mechanisms

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-15
Completion: 2025-08-13
Conditions
Sleep Problems Insomnia
Interventions
OTHER
No Results Yet
NCT06785012 | RECRUITING | PHASE2
124 Participants

A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-26
Completion: 2026-06-26
Conditions
Depressive Disorder, Major
Interventions
DRUG
No Results Yet
NCT06780111 | RECRUITING | PHASE1/PHASE2
228 Participants

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-30
Completion: 2032-01-04
Conditions
Esophageal Squamous Cell Carcinoma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06779851 | RECRUITING | PHASE1
100 Participants

A Study to Evaluate Safety and Tolerability of BPT567 in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-15
Completion: 2027-12-31
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06777368 | RECRUITING
225 Participants

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-06
Completion: 2029-03-31
Conditions
Aortic Stenosis
Interventions
DEVICE
No Results Yet
NCT06773962 | RECRUITING | PHASE2
62 Participants

A Phase 2a Multicenter Clinical Trial of TB006 in Participants With Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-20
Completion: 2025-12-29
Conditions
Parkinson's Disease (PD)
Interventions
DRUG
No Results Yet
NCT06771115 | COMPLETED | PHASE2
176 Participants

Phase 2a Placebo-Controlled Study of VTX3232 Alone or in Combination With Semaglutide in Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-07
Completion: 2025-09-10
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06767319 | COMPLETED
79 Participants

Prospective, Multi-center, Non-interventional, Open Label, Randomized (Depth of Focus Testing Sequences), Clinical Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-18
Completion: 2025-03-11
Conditions
Depth of Focus
Interventions
OTHER
No Results Yet
NCT06756932 | RECRUITING | PHASE1
120 Participants

BGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-04
Completion: 2027-07-30
Conditions
Hormone-receptor-positive Breast Cancer HER2-negative Breast Cancer Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT06750094 | RECRUITING | PHASE3
700 Participants

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-12
Completion: 2027-12-15
Conditions
Colorectal Neoplasms
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06749496 | COMPLETED | NA
134 Participants

Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-07
Completion: 2025-03-20
Conditions
Astigmatism
Interventions
DEVICE
No Results Yet
NCT06747117 | RECRUITING
300 Participants

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-18
Completion: 2028-06-30
Conditions
Lower Extremity Acute Limb Ischemia LE ALI
Interventions
DEVICE
No Results Yet
NCT06745921 | ACTIVE_NOT_RECRUITING | PHASE1
30 Participants

Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-24
Completion: 2026-10-01
Conditions
West Nile Viral Infection
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06745024 | RECRUITING | PHASE3
280 Participants

Comparing Radiation Therapy to Usual Care for Patients With High-Risk Bone Asymptomatic Metastases, PREEMPT Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-14
Completion: 2029-02-01
Conditions
Metastatic Malignant Neoplasm in the Bone Metastatic Malignant Solid Neoplasm
Interventions
OTHER PROCEDURE RADIATION
No Results Yet
NCT06742996 | RECRUITING | PHASE3
300 Participants

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-05
Completion: 2029-03-31
Conditions
Mantle Cell Lymphoma B Cell Lymphoma
Interventions
DRUG
No Results Yet
NCT06742853 | COMPLETED | PHASE1
81 Participants

A Study to Investigate the Pharmacokinetics, Safety, Tolerability, and Efficacy of AZD0780 With Ezetimibe Combinations in Healthy Adults With Elevated LDL-C.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-20
Completion: 2025-10-29
Conditions
Dyslipidemia
Interventions
DRUG
No Results Yet
NCT06741969 | RECRUITING | PHASE3
600 Participants

Nipocalimab in Moderate to Severe Sjogren's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-04
Completion: 2028-01-01
Conditions
Sjogrens Syndrome
Interventions
DRUG
No Results Yet
NCT06741228 | RECRUITING | PHASE3
200 Participants

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Voyage)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-11
Completion: 2026-05-31
Conditions
Generalized Anxiety Disorder
Interventions
OTHER DRUG
No Results Yet
NCT06739811 | RECRUITING | NA
40 Participants

Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-26
Completion: 2026-06-30
Conditions
Type I Diabetes
Interventions
DEVICE
No Results Yet
NCT06736990 | RECRUITING | PHASE2
150 Participants

A Phase 2 Study of CAL101 in Patients With Idiopathic Pulmonary Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-20
Completion: 2027-08-31
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
DRUG
No Results Yet
NCT06735950 | NOT_YET_RECRUITING | NA
200 Participants

The Volunteering-in-Place Program for Apathetic Assisted Living Residents With ADRD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-31
Completion: 2027-12-31
Conditions
Apathy in Dementia
Interventions
BEHAVIORAL
No Results Yet
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