Clinical Trials

NCT06735833 | RECRUITING | NA
50 Participants

MMA Embolization for Refractory Chronic Migraine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-23
Completion: 2028-12-25
Conditions
Migraine
Interventions
DEVICE
No Results Yet
NCT06735209 | ACTIVE_NOT_RECRUITING | PHASE1
22 Participants

First-in-Human PfSPZ-LARC2 Vaccination/CHMI

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-23
Completion: 2027-02-01
Conditions
Malaria
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06733363 | RECRUITING | PHASE2
344 Participants

A Cruciferous Vegetable Eating Program for the Reduction of Cancer Recurrence and Progression in Patients With Non-muscle Invasive Bladder Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-15
Completion: 2029-02-28
Conditions
Non-Muscle Invasive Bladder Carcinoma Recurrent Bladder Carcinoma Recurrent Non-Muscle Invasive Bladder Carcinoma Stage 0a Bladder Cancer AJCC v8 Stage 1 Bladder Cancer AJCC v8
Interventions
BEHAVIORAL
No Results Yet
NCT06727422 | NOT_YET_RECRUITING | PHASE2
225 Participants

Efficacy of Rifaximin With NAC in IBS-D

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-15
Completion: 2026-04-01
Conditions
IBS (Irritable Bowel Syndrome) IBS-D (Diarrhea-predominant)
Interventions
DRUG
No Results Yet
NCT06712745 | RECRUITING | EARLY_PHASE1
30 Participants

Feasibility Study of Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy (PULSAR) for Cancers of the Central Lung

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-09-19
Completion: 2028-12-31
Conditions
Cancer, Lung Metastasis
Interventions
RADIATION
No Results Yet
NCT06709521 | RECRUITING | PHASE4
150 Participants

Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-12
Completion: 2026-06-30
Conditions
Bacterial Infection
Interventions
DRUG
No Results Yet
NCT06709014 | RECRUITING | PHASE3
760 Participants

A Double-blind Dual Study Assessing Safety and Efficacy of Buntanetap in Participants With Early AD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-04
Completion: 2027-12-31
Conditions
Early Alzheimers Disease
Interventions
DRUG
No Results Yet
NCT06702917 | RECRUITING
50 Participants

GSI Cardiac on Revolution Apex - US

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-09-10
Completion: 2026-03-31
Conditions
Coronary Computed Tomographic Angiography Myocardial Infarction (MI) Cardiac Catheterization
Interventions
DEVICE OTHER
No Results Yet
NCT06701006 | RECRUITING | NA
100 Participants

Integrated Suicide Supports and Safety Planning for Youth

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-08-19
Completion: 2026-04-30
Conditions
Suicidal Ideation Suicidal Behavior
Interventions
OTHER
No Results Yet
NCT06693778 | RECRUITING
3000 Participants

Utilizing Electronic Clinical Decision Support to Enhance mTBI Care at the Primary Care Point of Entry

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2023-04-01
Completion: 2026-03-31
Conditions
Brain Concussion Mild Traumatic Brain Injury
Interventions
OTHER
No Results Yet
NCT06692907 | RECRUITING | PHASE2
72 Participants

Efficacy Study of IM Administered CssBA+dmLT Against Moderate-severe Diarrhea in Human Infection Model With ETEC Strain B7A in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-31
Completion: 2026-02-20
Conditions
Escherichia Infection
Interventions
OTHER BIOLOGICAL
No Results Yet
NCT06690996 | ACTIVE_NOT_RECRUITING | PHASE1
118 Participants

A Study of LY4005130 in Healthy Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-11-08
Completion: 2026-04-30
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT06681220 | NOT_YET_RECRUITING | PHASE1/PHASE2
166 Participants

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-17
Completion: 2029-12-31
Conditions
Relapsed Small Cell Lung Cancer Recurrent Small Cell Lung Cancer
Interventions
COMBINATION_PRODUCT DRUG
No Results Yet
NCT06675136 | RECRUITING | PHASE1
30 Participants

Nab-Paclitaxel PIPAC in Combination With Paclitaxel and Ramucirumab for the Treatment of Stomach Cancer With Peritoneal Metastases

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-29
Completion: 2029-01-14
Conditions
Clinical Stage IVB Gastric Cancer AJCC v8 Metastatic Gastric Adenocarcinoma Metastatic Malignant Neoplasm in the Peritoneum
Interventions
PROCEDURE OTHER DRUG BIOLOGICAL
No Results Yet
NCT06671613 | RECRUITING | NA
66 Participants

Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-27
Completion: 2029-12-31
Conditions
Stage IV NSCLC NSCLC Immunotherapy Fasting Mimicking Diet
Interventions
DIETARY_SUPPLEMENT COMBINATION_PRODUCT
No Results Yet
NCT06667908 | RECRUITING | PHASE2
130 Participants

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-06
Completion: 2028-12-31
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG BIOLOGICAL RADIATION
No Results Yet
NCT06667414 | RECRUITING
600 Participants

Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-02
Completion: 2028-09-24
Conditions
Huntington Disease
No Results Yet
NCT06667076 | RECRUITING | PHASE2
480 Participants

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-16
Completion: 2029-05-23
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
No Results Yet
NCT06665308 | RECRUITING
110 Participants

Cognitive Status, Fatigue and Inflammation in Patients With Immune Thrombocytopenia (ITP)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-13
Completion: 2025-12-12
Conditions
Chronic Immune Thrombocytopenia Primary Immune Thrombocytopenia Adult Immune Thrombocytopenia
Interventions
OTHER
No Results Yet
NCT06664788 | RECRUITING | NA
108 Participants

A Study of ETHIZIA Versus SURGICEL Original in Controlling Soft Tissue Bleeding During Open Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-16
Completion: 2026-01-30
Conditions
Hemostasis Hemostatic Techniques
Interventions
DEVICE
No Results Yet
NCT06664619 | RECRUITING | PHASE3
724 Participants

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-12
Completion: 2026-05-31
Conditions
Asthma
Interventions
DRUG
No Results Yet
NCT06663332 | RECRUITING | PHASE3
196 Participants

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-29
Completion: 2031-12-12
Conditions
Crohns Disease Colitis, Ulcerative Arthritis, Psoriatic Arthritis, Juvenile
Interventions
DRUG
No Results Yet
NCT06663319 | RECRUITING | PHASE1
170 Participants

A Study of JNJ-89402638 for Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-15
Completion: 2028-02-25
Conditions
Unresectable Metastatic Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT06662786 | RECRUITING | PHASE3
1000 Participants

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-18
Completion: 2028-12-15
Conditions
Colorectal Neoplasms
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06662162 | RECRUITING | NA
100 Participants

Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-07
Completion: 2027-03-31
Conditions
Age-Related Macular Degeneration Age-related Macular Degeneration (ARMD) Intermediate AMD Geographic Atrophy Secondary to Age-related Macular Degeneration
Interventions
DEVICE
No Results Yet
NCT06660563 | ACTIVE_NOT_RECRUITING | PHASE1
19 Participants

A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-22
Completion: 2026-09-21
Conditions
Lymphoma, Non-Hodgkin
Interventions
DRUG
No Results Yet
NCT06657144 | RECRUITING | PHASE1
154 Participants

A Study of CHS-114 in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-01
Completion: 2027-05-31
Conditions
Metastatic Solid Tumor Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06655740 | ACTIVE_NOT_RECRUITING | NA
16 Participants

Safety, Tolerability, and Effectiveness of Duodenal Mucosal RF Vapor Ablation for Insulin Elimination in Type-2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-01
Completion: 2027-06-30
Conditions
Diabetes Mellitus, Type 2
Interventions
DEVICE
No Results Yet
NCT06651528 | NOT_YET_RECRUITING | NA
264 Participants

Trauma-informed Intervention to Reduce Substance Use and to Support Community Transition

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-31
Completion: 2029-09-30
Conditions
Substance Use Disorder (SUD)
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06646289 | RECRUITING | PHASE2
42 Participants

A Follow-on Study for Second-Eye Treatment for Participants Previously Treated With Gene Therapy for X-Linked Retinitis Pigmentosa (XLRP)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-10
Completion: 2030-10-24
Conditions
X-Linked Retinitis Pigmentosa
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06635889 | RECRUITING | PHASE2
116 Participants

Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-26
Completion: 2029-10-31
Conditions
Nephrolithiasis
Interventions
DRUG OTHER
No Results Yet
NCT06635785 | RECRUITING | PHASE1/PHASE2
204 Participants

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-26
Completion: 2026-06-30
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06635148 | RECRUITING | PHASE2
311 Participants

A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-19
Completion: 2029-08-24
Conditions
Geographic Atrophy Macular Degeneration
Interventions
DRUG OTHER
No Results Yet
NCT06635135 | TERMINATED | PHASE3
48 Participants

A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-19
Completion: 2025-04-09
Conditions
Depressive Disorder, Major Anhedonia
Interventions
DRUG OTHER
No Results Yet
NCT06634589 | RECRUITING | PHASE1/PHASE2
80 Participants

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-11-27
Completion: 2028-12-02
Conditions
B-cell Malignancy Relapsed Cancer Refractory Cancer B-cell Lymphoma
Interventions
DRUG
No Results Yet
NCT06631638 | RECRUITING | NA
118 Participants

EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-30
Completion: 2027-12-31
Conditions
Osteoarthritis Traumatic Arthritis Rheumatoid Arthritis Congential Hip Dysplasia Avascular Necrosis of the Femoral Head Certain Cases of Ankylosis
Interventions
DEVICE
No Results Yet
NCT06630429 | ACTIVE_NOT_RECRUITING
100 Participants

A Pilot Study of Blood-based Biomarkers for Response to Immune Checkpoint Inhibitors

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2020-09-02
Completion: 2026-07-31
Conditions
Non-Small Cell Lung Cancer Renal Cell Carcinoma (RCC)
Interventions
OTHER
No Results Yet
NCT06628934 | ACTIVE_NOT_RECRUITING
600 Participants

Wearable Gait Sensors

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2017-06-23
Completion: 2025-12-31
Conditions
Spinocerebellar Ataxia
No Results Yet
NCT06625775 | RECRUITING | PHASE1
392 Participants

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-29
Completion: 2028-11-30
Conditions
Solid Tumor, Adult Metastatic Breast Cancer Advanced Breast Cancer HER2 Mutation-Related Tumors HER2-positive Metastatic Breast Cancer KRAS Mutant Metastatic Colorectal Cancer Metastatic Lung Cancer Metastatic Colorectal Cancer Advanced Lung Cancer HR-positive, HER2-negative Advanced Breast Cancer HER2-positive Advanced Breast Cancer
Interventions
DRUG
No Results Yet
NCT06625177 | RECRUITING | PHASE1
36 Participants

A Trial to Test the Safety and Efficacy of TEV-53408 in Treating Vitiligo

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-11-11
Completion: 2026-05-09
Conditions
Vitiligo
Interventions
DRUG
No Results Yet
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