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Clinical Trials

NCT06624228 | ACTIVE_NOT_RECRUITING | PHASE3
684 Participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-21
Completion: 2026-02-03
Conditions
Psoriatic Arthritis
Interventions
DRUG
No Results Yet
NCT06624085 | RECRUITING | PHASE1
50 Participants

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-28
Completion: 2030-03-31
Conditions
Lymphoma
Interventions
DRUG
No Results Yet
NCT06620042 | COMPLETED | PHASE2
20 Participants

FMRI of Patients Receiving IV Ketamine for Treatment Resistant Bipolar Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-11-12
Completion: 2025-10-31
Conditions
Bipolar Depression Treatment Resistant Bipolar Depression
Interventions
DRUG OTHER
No Results Yet
NCT06618534 | RECRUITING | PHASE2
1120 Participants

Azithromycin for Meningococcal Carriage

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-11-12
Completion: 2026-05-31
Conditions
Meningococcal Infections
Interventions
DRUG
No Results Yet
NCT06615050 | RECRUITING | PHASE3
572 Participants

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-02
Completion: 2031-01-17
Conditions
Graft-versus-host Disease (GVHD)
Interventions
DRUG
No Results Yet
NCT06614309 | RECRUITING | NA
45 Participants

Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-24
Completion: 2026-04-30
Conditions
Long COVID
Interventions
OTHER
No Results Yet
NCT06613568 | RECRUITING | NA
50 Participants

Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-06
Completion: 2027-03-31
Conditions
End Stage Kidney Disease
Interventions
DEVICE
No Results Yet
NCT06608485 | RECRUITING
165 Participants

A Study of HARMONIC 700 Shears With Advanced Hemostasis in Pediatric and Adult Surgical Procedures

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-23
Completion: 2026-05-15
Conditions
Pediatric Surgical Procedures Adult Surgical Procedures Adult Gynecological Procedures Adult Urological Procedures Adult Thoracic Procedures
Interventions
DEVICE
No Results Yet
NCT06608212 | ACTIVE_NOT_RECRUITING
150000 Participants

An Observational Study to Learn More About How Safe Finerenone is and How Well it Works in People With Chronic Kidney Disease and Type 2 Diabetes in Routine Medical Care in the United States

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-09
Completion: 2025-12-31
Conditions
Chronic Kidney Disease Type 2 Diabetes Mellitus
Interventions
DRUG
No Results Yet
NCT06607458 | RECRUITING | PHASE2
90 Participants

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-08-05
Completion: 2026-12-31
Conditions
Refractory Metastatic Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT06596577 | ENROLLING_BY_INVITATION | PHASE3
18000 Participants

Nudging Effective and Equitable Delivery of Specialty Palliative Care

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-08-06
Completion: 2028-03-01
Conditions
Serious Illness Palliative
Interventions
BEHAVIORAL
No Results Yet
NCT06595953 | RECRUITING | PHASE2
150 Participants

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-04
Completion: 2029-10-01
Conditions
Psychiatric Disorders Anxiety Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT06593483 | COMPLETED | NA
120 Participants

Increasing Effectiveness of an Alcohol Use Reduction Exercise Using Self-Talk Videos

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-15
Completion: 2024-11-26
Conditions
Heavy Drinking
Interventions
BEHAVIORAL
No Results Yet
NCT06589115 | WITHDRAWN | NA
0 Participants

Blood Flow Restriction Therapy Improves Tibial Plateau Fracture Recovery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-01
Completion: 2027-12-01
Conditions
Tibial Plateau Fractures
Interventions
OTHER
No Results Yet
NCT06588738 | ACTIVE_NOT_RECRUITING | PHASE3
840 Participants

A Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-20
Completion: 2025-09-23
Conditions
Plaque Psoriasis
Interventions
DRUG
No Results Yet
NCT06588634 | RECRUITING | NA
200 Participants

The PERSEVERE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-16
Completion: 2026-12-31
Conditions
Pulmonary Embolism Pulmonary Thromboembolism
Interventions
DEVICE PROCEDURE
No Results Yet
NCT06586112 | ACTIVE_NOT_RECRUITING | PHASE3
840 Participants

A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-25
Completion: 2025-09-19
Conditions
Plaque Psoriasis
Interventions
DRUG
No Results Yet
NCT06585774 | RECRUITING | PHASE3
240 Participants

A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-21
Completion: 2027-09-28
Conditions
Chronic Graft-versus-host-disease
Interventions
DRUG
No Results Yet
NCT06581406 | RECRUITING | PHASE2/PHASE3
280 Participants

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-17
Completion: 2030-01-31
Conditions
Metastatic Uveal Melanoma
Interventions
BIOLOGICAL
No Results Yet
NCT06579794 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated: 2025-11-10
No Results Yet
NCT06577025 | ACTIVE_NOT_RECRUITING | PHASE2
43 Participants

A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-20
Completion: 2030-07-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06576427 | RECRUITING | NA
145 Participants

Selective Pulmonary-artery Intervention to Reduce Acute Right-heart tEnsion-II

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-15
Completion: 2026-02-28
Conditions
Pulmonary Embolism
Interventions
DEVICE
No Results Yet
NCT06576076 | RECRUITING | NA
200 Participants

Cannabis, Linked Emotions, and Adolescent Risk Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-18
Completion: 2028-12-31
Conditions
Cannabis Use Depression Suicidal Ideation Adolescent Behavior
Interventions
BEHAVIORAL
No Results Yet
NCT06575192 | RECRUITING | PHASE3
783 Participants

Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-11-05
Completion: 2029-12-31
Conditions
Breast Reconstruction
Interventions
DEVICE OTHER
No Results Yet
NCT06571383 | ACTIVE_NOT_RECRUITING | PHASE4
500 Participants

STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-17
Completion: 2028-11-15
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06567717 | RECRUITING | PHASE2
60 Participants

Zinc and Nicotinamide Riboside for Idiopathic Pulmonary Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-03
Completion: 2027-01-31
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
DRUG OTHER
No Results Yet
NCT06552741 | RECRUITING
10000 Participants

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-04
Completion: 2045-01-01
Conditions
Substance Use Disorder Alcohol Use Disorder
No Results Yet
NCT06551506 | ACTIVE_NOT_RECRUITING | PHASE4
181 Participants

The Immunology and Safety of Maternal RSV Vaccination (ABRYSVO), Infant Nirsevimab (BEYFORTUS) Immunization, or Both Products

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-19
Completion: 2026-05-31
Conditions
Respiratory Syncytial Virus Infection
Interventions
BIOLOGICAL
No Results Yet
NCT06550895 | ACTIVE_NOT_RECRUITING | PHASE2
11 Participants

A Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-16
Completion: 2026-08-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06549595 | RECRUITING | PHASE3
1015 Participants

A Study of AZD0486 Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-07
Completion: 2031-11-26
Conditions
Untreated Follicular Lymphoma
Interventions
DRUG
No Results Yet
NCT06549036 | NOT_YET_RECRUITING | NA
228 Participants

Veteran Peer Navigators to Promote Shared Decision Making for PSA Screening

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-05
Completion: 2028-03-01
Conditions
Prostate Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06548360 | RECRUITING | PHASE3
180 Participants

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-24
Completion: 2026-08-10
Conditions
NonSegmental Vitiligo
Interventions
DRUG
No Results Yet
NCT06547489 | RECRUITING | PHASE2
164 Participants

GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-03
Completion: 2026-08-31
Conditions
Major Depressive Disorder
Interventions
DRUG
No Results Yet
NCT06545682 | RECRUITING | PHASE1
50 Participants

Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-15
Completion: 2027-08-03
Conditions
Melanoma (Skin Cancer) Breast Cancer Brain Metastasases
Interventions
DRUG
No Results Yet
NCT06544616 | RECRUITING | PHASE2
498 Participants

A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-22
Completion: 2031-07-17
Conditions
Preclinical Alzheimer's Disease
Interventions
DRUG
No Results Yet
NCT06540144 | ENROLLING_BY_INVITATION | PHASE3
12 Participants

An Extension Study Evaluating 6-week Treatment Cycles of Rozanolixizumab in Pediatric Study Participants With Generalized Myasthenia Gravis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-08
Completion: 2027-08-17
Conditions
Generalized Myasthenia Gravis
Interventions
DRUG
No Results Yet
NCT06535178 | RECRUITING | NA
30 Participants

The Influence of Sleep on Cardiovascular Outcomes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-01
Completion: 2026-09-30
Conditions
Circadian Rhythm Cardiometabolic Health Vascular Health Pain
Interventions
BEHAVIORAL
No Results Yet
NCT06533098 | RECRUITING | PHASE3
50 Participants

A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-10
Completion: 2027-12-15
Conditions
Thrombocytopenia, Neonatal Alloimmune
Interventions
DRUG
No Results Yet
NCT06529835 | RECRUITING | NA
80 Participants

A Comparison of NeuroSpan Bridge, NeuraGen Nerve Guide, and Nerve Autograft for Peripheral Nerve Repair

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-21
Completion: 2027-12-31
Conditions
Peripheral Nerve Injuries
Interventions
DEVICE
No Results Yet
NCT06528496 | RECRUITING | PHASE2
45 Participants

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-22
Completion: 2029-07-22
Conditions
High-risk Neuroblastoma Neuroblastoma Childhood Neuroblastoma
Interventions
BIOLOGICAL DRUG
No Results Yet
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