Clinical Trials

NCT06527872 | RECRUITING
300 Participants

Study to Assess Real-world Effectiveness of Belimumab for Treatment of Adults With LN

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-04
Completion: 2029-03-29
Conditions
Lupus Nephritis
Interventions
OTHER
No Results Yet
NCT06524973 | RECRUITING | NA
136 Participants

Telehealth Self-Management Coaching Sessions to Improve Quality of Life in Pancreatic Cancer Survivors and Their Family Care Givers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-07
Completion: 2027-05-03
Conditions
Metastatic Pancreatic Adenocarcinoma
Interventions
OTHER
No Results Yet
NCT06517758 | RECRUITING | PHASE3
146 Participants

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 75 Years With gMG.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-31
Completion: 2026-12-28
Conditions
Generalized Myasthenia Gravis
Interventions
DRUG OTHER
No Results Yet
NCT06516965 | RECRUITING | PHASE3
330 Participants

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-10
Completion: 2026-10-19
Conditions
Prurigo Nodularis
Interventions
DRUG
No Results Yet
NCT06516952 | RECRUITING | PHASE3
330 Participants

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-10
Completion: 2026-10-19
Conditions
Prurigo Nodularis
Interventions
DRUG
No Results Yet
NCT06504914 | RECRUITING | NA
24 Participants

Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-02-05
Completion: 2026-06-30
Conditions
Hypertension Obesity Nutrition, Healthy
Interventions
BEHAVIORAL
No Results Yet
NCT06501625 | RECRUITING | PHASE1/PHASE2
52 Participants

Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-16
Completion: 2026-07-23
Conditions
Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation
Interventions
DRUG
No Results Yet
NCT06500884 | RECRUITING | PHASE2
130 Participants

A Study to Evaluate Preventive Treatments for Talquetamab-related Oral Toxicity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-26
Completion: 2026-04-15
Conditions
Relapse Multiple Myeloma Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06500455 | RECRUITING | PHASE3
269 Participants

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-12
Completion: 2028-06-30
Conditions
Anatomic Stage IV Breast Cancer AJCC v8 Metastatic Breast Carcinoma Metastatic Digestive System Carcinoma Metastatic Lung Non-Small Cell Carcinoma Metastatic Malignant Neoplasm in the Brain Metastatic Malignant Solid Neoplasm Metastatic Melanoma Metastatic Renal Cell Carcinoma Stage IV Lung Cancer AJCC v8 Stage IV Renal Cell Cancer AJCC v8
Interventions
PROCEDURE RADIATION
No Results Yet
NCT06486454 | RECRUITING
5000 Participants

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-14
Completion: 2026-11-30
Conditions
Liver Neoplasms Primary Liver Cancer Secondary Liver Cancer Tumor Liver Benign Liver Tumor
Interventions
DEVICE
No Results Yet
NCT06479447 | RECRUITING | NA
17000 Participants

Patient Outcome Reporting for Timely Assessments of Life With Post-Traumatic Stress Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-15
Completion: 2026-07-14
Conditions
PTSD
Interventions
OTHER
No Results Yet
NCT06478160 | RECRUITING | NA
216 Participants

Closed-blood Sampling Devices in the Adult Critically Ill Patient

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-11-11
Completion: 2026-06-07
Conditions
Acceptability of Health Care
Interventions
DEVICE OTHER
No Results Yet
NCT06477289 | RECRUITING
65 Participants

Peripheral Arterial Tonometry and Neurocognition in Sickle Cell Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-16
Completion: 2027-06-30
Conditions
Sickle Cell Disease
No Results Yet
NCT06472245 | RECRUITING | PHASE3
363 Participants

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-03
Completion: 2027-12-15
Conditions
Patients With Non-Small Cell Lung Cancer
Interventions
DRUG DEVICE
No Results Yet
NCT06472128 | RECRUITING | NA
200 Participants

Novel Digital Application for Patients With Acute Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-21
Completion: 2029-04-30
Conditions
Relapsed Adult Acute Myeloid Leukemia Primary Refractory Acute Myeloid Leukemia High Risk Acute Myeloid Leukemia
Interventions
BEHAVIORAL
No Results Yet
NCT06470087 | COMPLETED | NA
28 Participants

High Purity Type I Collagen Based Skin Substitute Vs Dehydrated Human Amnion/Chorion Membrane in Treatment of DFUs

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-03
Completion: 2024-09-15
Conditions
Diabetic Foot Ulcer (DFU)
Interventions
DEVICE OTHER
NCT06469944 | RECRUITING | PHASE1/PHASE2
130 Participants

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-20
Completion: 2027-01-17
Conditions
Gastroesophageal Junction Gastroesophageal Adenocarcinoma Esophageal Neoplasms Esophageal Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06469151 | COMPLETED | PHASE1
84 Participants

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD5148 in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-24
Completion: 2025-10-22
Conditions
Healthy Participants
Interventions
DRUG
No Results Yet
NCT06464926 | RECRUITING | NA
148 Participants

Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterraยฎ Therapy System (NAVIGATE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-23
Completion: 2030-06-30
Conditions
Nausea Vomiting
Interventions
DEVICE
No Results Yet
NCT06461897 | RECRUITING | PHASE3
675 Participants

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-19
Completion: 2030-07-31
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
NCT06456762 | RECRUITING | NA
90 Participants

Text-messaging Intervention to Support Parents After Their Child's Psychiatric Emergency

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-01
Completion: 2026-12-31
Conditions
Parents Self Efficacy Mental Health Literacy Psychiatric Emergency
Interventions
BEHAVIORAL
No Results Yet
NCT06455098 | RECRUITING | NA
440 Participants

A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-28
Completion: 2026-05-30
Conditions
Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT06453694 | RECRUITING | PHASE2
20 Participants

Efgartigimod for the Treatment of Acute Optic Neuritis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-08-12
Completion: 2026-12-31
Conditions
Optic Neuritis
Interventions
DRUG
No Results Yet
NCT06449651 | RECRUITING | PHASE3
39 Participants

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-11-11
Completion: 2029-12-05
Conditions
Thrombocytopenia, Neonatal Alloimmune
Interventions
DRUG
No Results Yet
NCT06445972 | RECRUITING | PHASE1/PHASE2
90 Participants

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-07
Completion: 2026-12-28
Conditions
Gastroesophageal Junction Gastroesophageal Adenocarcinoma Esophageal Neoplasms Esophageal Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06441968 | ACTIVE_NOT_RECRUITING | PHASE1
60 Participants

Safety and Immunogenicity Trial of MPV/S-2P SARS-CoV-2 Vaccine in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-01
Completion: 2025-11-13
Conditions
COVID-19
Interventions
BIOLOGICAL
No Results Yet
NCT06439836 | RECRUITING | PHASE1
27 Participants

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-05
Completion: 2027-06-01
Conditions
Metastatic Urothelial Carcinoma Unresectable Urothelial Carcinoma
Interventions
PROCEDURE BIOLOGICAL
No Results Yet
NCT06434337 | RECRUITING
600 Participants

Evaluation of a Novel Point-of-Care Diagnostic Test for Human Papillomavirus (HPV)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-23
Completion: 2026-03-31
Conditions
Human Papillomavirus
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06425991 | ACTIVE_NOT_RECRUITING | PHASE1
108 Participants

A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-07
Completion: 2027-02-28
Conditions
Relapsed or Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06420089 | RECRUITING | PHASE1
30 Participants

CD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) for T Cell Non-Hodgkin Lymphoma (NHL)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-04
Completion: 2028-08-30
Conditions
T Cell Non-Hodgkin Lymphoma
Interventions
DRUG
No Results Yet
NCT06418204 | RECRUITING
2000 Participants

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-30
Completion: 2028-08-31
Conditions
Breast Carcinoma Colorectal Carcinoma Lung Non-Small Cell Carcinoma Melanoma Non-Hodgkin Lymphoma
Interventions
OTHER
No Results Yet
NCT06414902 | RECRUITING | PHASE1
60 Participants

18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-04
Completion: 2027-10-01
Conditions
Esophageal Cancer
Interventions
DRUG
No Results Yet
NCT06408935 | RECRUITING | PHASE3
112 Participants

Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-17
Completion: 2027-06-08
Conditions
Crohn's Disease
Interventions
DRUG
No Results Yet
NCT06406751 | ENROLLING_BY_INVITATION | NA
50 Participants

Microbiome Effects of Extended Use of MI Paste in Elderly Removable Denture Wearers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-28
Completion: 2027-06-30
Conditions
Dental Prosthesis
Interventions
DEVICE
No Results Yet
NCT06403605 | COMPLETED | NA
148 Participants

Bioresorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-09-13
Completion: 2025-01-17
Conditions
Diabetic Foot Ulcer Ulcer Foot Diabetic Foot
Interventions
DEVICE
NCT06398639 | RECRUITING | NA
1500 Participants

Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-07
Completion: 2028-04-30
Conditions
Prostate Cancer Polygenic Risk Score
Interventions
OTHER
No Results Yet
NCT06398626 | RECRUITING
300 Participants

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-17
Completion: 2027-05-04
Conditions
Colitis, Ulcerative
Interventions
DRUG
No Results Yet
NCT06394869 | RECRUITING | NA
1000 Participants

Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-29
Completion: 2027-01-31
Conditions
Hematuria - Cause Not Known
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06393374 | RECRUITING | PHASE3
1530 Participants

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-24
Completion: 2030-12-16
Conditions
Triple-Negative Breast Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06385080 | RECRUITING | PHASE1/PHASE2
287 Participants

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-22
Completion: 2027-12-27
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
BIOLOGICAL DRUG
No Results Yet
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