Clinical Trials

NCT06384625 | COMPLETED | NA
20 Participants

Developing and Evaluating an Indoor Air Pollution Intervention Among Cardiovascular Patients: the AIRWISE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-24
Completion: 2025-11-05
Conditions
Coronary Heart Disease Cardiovascular Diseases Environmental Exposure
Interventions
OTHER
No Results Yet
NCT06377514 | COMPLETED | NA
223 Participants

Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-03
Completion: 2025-04-23
Conditions
Cataracts
Interventions
DEVICE
No Results Yet
NCT06366633 | COMPLETED | NA
5 Participants

Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-29
Completion: 2025-05-31
Conditions
Orthopedic Disorder Nontraumatic Injury Substance Use Upper Extremity Problem
Interventions
BEHAVIORAL
No Results Yet
NCT06345729 | RECRUITING | PHASE3
600 Participants

A Study of MK-1084 Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-24
Completion: 2029-02-19
Conditions
Non-small Cell Lung Cancer
Interventions
DRUG OTHER BIOLOGICAL
No Results Yet
NCT06343831 | RECRUITING | NA
15 Participants

Quantitative Assessment of Autologous Fat Transfer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-01-25
Completion: 2026-12-31
Conditions
Autologous Fat Grafting
Interventions
PROCEDURE
No Results Yet
NCT06335953 | COMPLETED | NA
360 Participants

ALIGN: Aligning Medications With What Matters Most (Demonstration)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-07
Completion: 2025-09-16
Conditions
Polypharmacy Alzheimer's Disease and Related Dementias Mild Cognitive Impairment
Interventions
BEHAVIORAL
No Results Yet
NCT06334133 | RECRUITING | PHASE3
150 Participants

Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-14
Completion: 2026-09-30
Conditions
Diabetes Mellitus, Type 1
Interventions
DRUG
No Results Yet
NCT06327152 | ACTIVE_NOT_RECRUITING | PHASE2
80 Participants

Caffeine Use in the Management of Preterm Infants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-02-22
Completion: 2026-12-31
Conditions
Apnea of Prematurity
Interventions
DRUG OTHER
No Results Yet
NCT06326411 | RECRUITING | PHASE1
230 Participants

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-09
Completion: 2028-11-30
Conditions
Oncology MEK Mutation RAF Gene Mutation Ras (KRAS or NRAS) Gene Mutation Melanoma NSCLC Glioma Solid Tumor, Adult MAPK Pathway Gene Mutation
Interventions
DRUG
No Results Yet
NCT06323980 | RECRUITING | NA
168 Participants

INHANCE Stemless Reverse Shoulder IDE

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-04
Completion: 2027-11-10
Conditions
Arthroplasty Replacement Shoulder
Interventions
DEVICE
No Results Yet
NCT06320808 | COMPLETED | NA
330 Participants

Evaluating FDA's Proposed Patient Medication Information Handout

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-03-03
Completion: 2024-03-04
Conditions
Knowledge Attitude
Interventions
OTHER
No Results Yet
NCT06320054 | RECRUITING | NA
100 Participants

Preventing Obstetric Complications With Dietary Intervention

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-12
Completion: 2026-02-28
Conditions
Gestational Diabetes Gestational Hypertension High Risk Pregnancy Preeclampsia
Interventions
BEHAVIORAL
No Results Yet
NCT06319820 | RECRUITING | PHASE3
560 Participants

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-18
Completion: 2028-06-28
Conditions
Non-Muscle Invasive Bladder Cancer
Interventions
COMBINATION_PRODUCT DRUG
No Results Yet
NCT06316973 | COMPLETED | PHASE1
32 Participants

A Clinical Study to Evaluate the Safety of CS-1103 in Healthy Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-02-07
Completion: 2024-05-30
Conditions
Substance Use Disorders Methamphetamine Abuse Methamphetamine Intoxication
Interventions
DRUG
NCT06313593 | RECRUITING | PHASE1
186 Participants

A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-08
Completion: 2028-10-09
Conditions
Myeloproliferative Neoplasms
Interventions
DRUG
No Results Yet
NCT06312176 | RECRUITING | PHASE3
1200 Participants

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-14
Completion: 2027-07-11
Conditions
Breast Neoplasms
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT06312137 | RECRUITING | PHASE3
780 Participants

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-03
Completion: 2034-02-21
Conditions
Non Small Cell Lung Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06311578 | RECRUITING | PHASE1
96 Participants

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-10
Completion: 2028-11-08
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06310655 | COMPLETED | NA
10 Participants

Online Proton Adaptive Radiotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-02
Completion: 2025-08-08
Conditions
Solid Tumor
Interventions
RADIATION
No Results Yet
NCT06297603 | ACTIVE_NOT_RECRUITING | PHASE3
320 Participants
NCT06296394 | RECRUITING
146 Participants

Health Outcomes of Parents With Cystic Fibrosis-Aim 2

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-29
Completion: 2030-02-01
Conditions
Cystic Fibrosis Parenthood Status
Interventions
OTHER
No Results Yet
NCT06295692 | ACTIVE_NOT_RECRUITING | PHASE3
19 Participants

A Study of JNJ-77242113 for the Treatment of Participants With Generalized Pustular Psoriasis or Erythrodermic Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-02-09
Completion: 2025-01-14
Conditions
Generalized Pustular Psoriasis Erythrodermic Psoriasis
Interventions
DRUG
No Results Yet
NCT06285318 | RECRUITING
900 Participants

A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2023-12-18
Completion: 2026-06-30
Conditions
Relapsed/Refractory Multiple Myeloma (RRMM)
Interventions
OTHER
No Results Yet
NCT06281756 | RECRUITING | EARLY_PHASE1
600 Participants

Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-03-20
Completion: 2027-11-30
Conditions
Insomnia Insomnia Chronic Insomnia, Primary Blood Pressure Blood Pressure, High
Interventions
BEHAVIORAL DRUG OTHER
No Results Yet
NCT06267729 | RECRUITING | PHASE1/PHASE2
60 Participants

Study of AZD0754 in Participants With Metastatic Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-03-12
Completion: 2026-11-24
Conditions
Metastatic Prostate Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT06264154 | RECRUITING | NA
210 Participants

The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-26
Completion: 2027-06-30
Conditions
Smoking Tobacco Use Cigarette Smoking E-Cig Use
Interventions
OTHER
No Results Yet
NCT06260163 | RECRUITING | PHASE3
120 Participants

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-01-19
Completion: 2028-05-22
Conditions
Colitis, Ulcerative
Interventions
DRUG
No Results Yet
NCT06258187 | ACTIVE_NOT_RECRUITING | NA
632 Participants

Pedi-Cap CO2 Detector for Face-mask Ventilation in the Delivery Room

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-03-01
Completion: 2026-01-31
Conditions
Neonatal Resuscitation Neonatal Disease
Interventions
DEVICE
No Results Yet
NCT06253806 | COMPLETED | PHASE2
48 Participants

Stellate Ganglion Block for COVID-induced Parosmia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-10-25
Completion: 2024-09-16
Conditions
COVID-19-Induced Parosmia
Interventions
DRUG
NCT06250322 | COMPLETED
307 Participants

A Multicenter, Observational, Single Arm Study of the TECNIS Presbyopia-correcting Intraocular Lens

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-10
Completion: 2025-06-30
Conditions
Cataracts
Interventions
DEVICE
No Results Yet
NCT06246942 | RECRUITING | NA
80 Participants

Physiology of Human Brain Connectivity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-13
Completion: 2027-04-15
Conditions
Healthy
Interventions
DEVICE DIAGNOSTIC_TEST
No Results Yet
NCT06237452 | RECRUITING | PHASE3
852 Participants

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-20
Completion: 2027-06-30
Conditions
Clostridium Difficile Clostridium Difficile Infections Clostridium Difficile Infection Recurrence Clostridioides Difficile Infection Clostridioides Difficile Infection Recurrence CDI C. Diff Infection Recurrent Clostridium Difficile Infection C.Difficile Diarrhea Diarrhea Infectious
Interventions
BIOLOGICAL
No Results Yet
NCT06234228 | RECRUITING | NA
1100 Participants

Examining Bluetooth Haptic Device Use for Pain and Anxiety Reduction in Vascular Access Procedures

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-25
Completion: 2025-10-31
Conditions
Pain Anxiety
Interventions
BEHAVIORAL
No Results Yet
NCT06233656 | ACTIVE_NOT_RECRUITING | NA
140 Participants

Acceptance and Commitment Therapy for Depressed People With Spinal Cord Injuries

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-30
Completion: 2027-02-28
Conditions
Depression Spinal Cord Injuries
Interventions
BEHAVIORAL
No Results Yet
NCT06220604 | ACTIVE_NOT_RECRUITING | PHASE3
731 Participants

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-ADVANCE 2)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-03-09
Completion: 2024-11-15
Conditions
Plaque Psoriasis
Interventions
DRUG
No Results Yet
NCT06218914 | RECRUITING | PHASE1
24 Participants

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-03-22
Completion: 2027-08-30
Conditions
Non-small Cell Lung Cancer Colorectal Carcinoma Pancreatic Ductal Adenocarcinoma Endometrial Cancer Solid Tumor, Adult KRAS G12D
Interventions
BIOLOGICAL
No Results Yet
NCT06211764 | ACTIVE_NOT_RECRUITING | PHASE3
272 Participants

A Study of TAR-200 Versus Intravesical Chemotherapy in Participants With Recurrent High-Risk Non-Muscle-Invasive Bladder Cancer (HR-NMIBC) After Bacillus Calmette-Guérin (BCG)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-09
Completion: 2030-11-27
Conditions
Non-Muscle Invasive Bladder Neoplasms
Interventions
DRUG
No Results Yet
NCT06208150 | RECRUITING | PHASE3
795 Participants
NCT06198010 | RECRUITING | NA
660 Participants

A Collaborative Intervention for Improving Cancer Pain Management in Rural and Hispanic Cancer Survivors (ASCENT)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-02-07
Completion: 2027-01-31
Conditions
Hematopoietic and Lymphoid System Neoplasm Malignant Solid Neoplasm Hematopoietic and Lymphatic System Neoplasm
Interventions
OTHER PROCEDURE BEHAVIORAL
No Results Yet
NCT06195891 | RECRUITING | PHASE1
33 Participants

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-24
Completion: 2027-06-21
Conditions
Acute Lymphoblastic Leukemia Acute Myeloid Leukemia Myelodysplastic Syndrome
Interventions
PROCEDURE DRUG BIOLOGICAL RADIATION
No Results Yet
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