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Clinical Trials

NCT06073119 | COMPLETED | PHASE2
221 Participants

A Study to Evaluate Efficacy and Safety of SAR441566 in Adults With Plaque Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-10-26
Completion: 2024-11-13
Conditions
Psoriasis
Interventions
DRUG
Results Available
NCT06066138 | RECRUITING | PHASE1
40 Participants

A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-04
Completion: 2026-01-31
Conditions
Locally Advanced Alveolar Soft Part Sarcoma Metastatic Alveolar Soft Part Sarcoma Locally Advanced Non Small Cell Lung Cancer Metastatic Non Small Cell Lung Cancer Locally Advanced Small Cell Lung Cancer Metastatic Small Cell Lung Cancer Locally Advanced Hepatocellular Carcinoma Metastatic Hepatocellular Carcinoma Locally Advanced Melanoma Metastatic Melanoma
Interventions
DRUG
No Results Yet
NCT06059963 | RECRUITING
12000 Participants

A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-01-18
Completion: 2026-10-30
Conditions
Colorectal Cancer Advanced Adenocarcinoma
Interventions
DEVICE
No Results Yet
NCT06058039 | RECRUITING | PHASE3
332 Participants

Study to Assess the Effects of Oral NMRA-335140 in Participants With Major Depressive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-12-21
Completion: 2026-02-28
Conditions
Major Depressive Disorder
Interventions
DRUG
No Results Yet
NCT06058013 | RECRUITING | PHASE3
332 Participants

Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-12-20
Completion: 2026-05-31
Conditions
Major Depressive Disorder
Interventions
DRUG
No Results Yet
NCT06057454 | COMPLETED | PHASE1
9 Participants

R-5280 in Newly Diagnosed Patients With Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-12-05
Completion: 2025-11-05
Conditions
Type 1 Diabetes Type 1 Diabetes (Juvenile Onset) Diabetes Mellitus, Type 1
Interventions
DRUG OTHER
No Results Yet
NCT06055881 | RECRUITING | NA
45 Participants

Primary Breast Oligoprogressive Sites Treated With Radiotherapy to Obviate the Need to Change Systemic Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-10-23
Completion: 2027-05-01
Conditions
Breast Carcinoma Anatomic Stage IV Breast Cancer AJCC v8 Metastatic Breast Cancer
Interventions
PROCEDURE OTHER RADIATION
No Results Yet
NCT06049017 | ACTIVE_NOT_RECRUITING | PHASE2
252 Participants

A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-10-09
Completion: 2024-09-26
Conditions
Colitis, Ulcerative
Interventions
DRUG
No Results Yet
NCT06047509 | ACTIVE_NOT_RECRUITING | NA
2 Participants

Focal Laser Ablation of Prostate Cancer: A Feasibility Study Using MRI/US Image Fusion for Guidance

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-09-14
Completion: 2026-10-01
Conditions
Prostate Cancer
Interventions
PROCEDURE
No Results Yet
NCT06045754 | RECRUITING | PHASE4
100 Participants

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-18
Completion: 2027-06-28
Conditions
Crohn's Disease
Interventions
DRUG
No Results Yet
NCT06045689 | ACTIVE_NOT_RECRUITING | PHASE3
106 Participants

A Study to Assess Luspatercept in Lower-risk Myelodysplastic Syndrome Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-10-05
Completion: 2025-10-01
Conditions
Myelodysplastic Syndromes
Interventions
DRUG
No Results Yet
NCT06044337 | ENROLLING_BY_INVITATION | PHASE3
322 Participants

A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-10-03
Completion: 2029-06-26
Conditions
Subacute Cutaneous Lupus Erythematosus Chronic Cutaneous Lupus Erythematosus
Interventions
DRUG
No Results Yet
NCT06034743 | COMPLETED | PHASE3
796 Participants

A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-11-22
Completion: 2025-05-21
Conditions
Uncontrolled Hypertension Resistant Hypertension
Interventions
DRUG
No Results Yet
NCT06029439 | RECRUITING | PHASE3
1000 Participants

Study to Assess the Safety and Effectiveness of NMRA-335140-501

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-11-10
Completion: 2027-06-30
Conditions
Major Depressive Disorder
Interventions
DRUG
No Results Yet
NCT06025747 | RECRUITING | PHASE1
18 Participants

Evaluation of Abemaciclib and Radiation Therapy Before Surgery for the Treatment of High-Risk Adipocytic Retroperitoneal Sarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-19
Completion: 2027-03-03
Conditions
Retroperitoneal Sarcoma
Interventions
DRUG PROCEDURE RADIATION
No Results Yet
NCT06015893 | RECRUITING | PHASE2
52 Participants

Semaglutide Therapy for Alcohol Reduction (STAR)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-10-17
Completion: 2030-12-31
Conditions
Addiction Alcohol Use Disorder
Interventions
BEHAVIORAL DRUG
No Results Yet
NCT06013995 | RECRUITING | PHASE1
44 Participants

A Study to Investigate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986326 in Adult Participants With Different Forms of Lupus

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-09-21
Completion: 2026-04-12
Conditions
Lupus
Interventions
DRUG OTHER
No Results Yet
NCT06013241 | COMPLETED | PHASE2
288 Participants

A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-10-30
Completion: 2025-09-30
Conditions
Chronic Rhinosinusitis Without Nasal Polyps
Interventions
DRUG
No Results Yet
NCT06008860 | RECRUITING | PHASE4
280 Participants

A Pilot Clinical Evaluation of Asteproยฎ Nasal Spray for Management of Early SARS-CoV-2 Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-07-01
Completion: 2026-12-31
Conditions
COVID-19
Interventions
DRUG OTHER
No Results Yet
NCT06008730 | RECRUITING | PHASE2
20 Participants

Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-12-13
Completion: 2026-12-31
Conditions
Resectable Lung Non-Small Cell Carcinoma
Interventions
PROCEDURE RADIATION OTHER
No Results Yet
NCT06008275 | RECRUITING | EARLY_PHASE1
20 Participants

Neratinib in Combination With Ruxolitinib in Patients With mTNBC

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-16
Completion: 2026-06-30
Conditions
Metastatic Triple-Negative Breast Carcinoma Breast Cancer
Interventions
DRUG
No Results Yet
NCT06008158 | SUSPENDED | PHASE2
48 Participants

Evaluation of a Once Per Day Regimen of Accelerated Partial Breast Irradiation for Improved Breast Appearance in Patients With Low Risk, Hormone Responsive Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-09-29
Completion: 2026-06-15
Conditions
Anatomic Stage 0 Breast Cancer AJCC v8 Anatomic Stage IA Breast Cancer AJCC v8 Estrogen Receptor-Positive Breast Carcinoma HER2-Negative Breast Carcinoma
Interventions
RADIATION
No Results Yet
NCT06006962 | RECRUITING | NA
128 Participants

Aging Well Through Interactions and Scientific Education - Action Plan (AgeWISE-AP)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-01-01
Completion: 2026-05-31
Conditions
Cognitive Aging
Interventions
OTHER
No Results Yet
NCT06006273 | RECRUITING | PHASE1
48 Participants

A Phase Ib Trial of Eribulin in Combination With Irinotecan and Temozolamide in Children With Relapsed or Refractory Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-08-16
Completion: 2026-12-31
Conditions
Refractory Solid Tumors
Interventions
DRUG
No Results Yet
NCT06003881 | APPROVED_FOR_MARKETING

Compassionate Use of Pozelimab in Patients With CD55-Deficient Protein-Losing Enteropathy

Study Type: EXPANDED_ACCESS
Last Updated: 2025-11-10
Conditions
CD55-Deficient Protein-Losing Enteropathy
Interventions
DRUG
No Results Yet
NCT06001788 | RECRUITING | PHASE1
171 Participants

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-02-22
Completion: 2026-08-31
Conditions
AML AML With Mutated NPM1 Hematologic Malignancy KMT2Ar NPM1 Mutation MLL Rearrangement Leukemia Acute Myeloid Leukemia Leukemia, Myeloid Leukemia, Myeloid, Acute Acute Leukemia Neoplasms by Histologic Type
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05992909 | RECRUITING
20 Participants

Prophylactic Lymphovenous Bypass Procedure Following Inguinal Lymphadenectomy: A Prospective Observational Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2023-08-02
Completion: 2027-08-01
Conditions
Lymphadenectomy
Interventions
PROCEDURE
No Results Yet
NCT05989815 | COMPLETED | NA
30 Participants

Effect of Whole-body Photobiomodulation on Muscular Performance Enhancement.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-07-10
Completion: 2023-11-10
Conditions
Sports Performance Injury Prevention Muscle Damage Musculoskeletal Pain
Interventions
OTHER DEVICE
Results Available
NCT05988385 | RECRUITING | NA
200 Participants

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-22
Completion: 2027-06-30
Conditions
Obstructive Sleep Apnea Cognitive Decline
Interventions
DEVICE
No Results Yet
NCT05987449 | RECRUITING | PHASE1/PHASE2
60 Participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-09-21
Completion: 2030-06-16
Conditions
Hemophilia A
Interventions
DRUG
No Results Yet
NCT05987332 | RECRUITING | PHASE2/PHASE3
420 Participants

IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-10-31
Completion: 2027-01-15
Conditions
Metastatic Uveal Melanoma
Interventions
DRUG
No Results Yet
NCT05986240 | RECRUITING | PHASE1
38 Participants

Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AML

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-08
Completion: 2027-06-30
Conditions
AML/MDS Acute Myeloid Leukemia Myelodysplastic Syndromes
Interventions
DRUG COMBINATION_PRODUCT
No Results Yet
NCT05986097 | COMPLETED | PHASE1/PHASE2
119 Participants

The Breakfast Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-08-02
Completion: 2025-10-09
Conditions
Type 2 Diabetes
Interventions
BEHAVIORAL
No Results Yet
NCT05980949 | RECRUITING | PHASE3
800 Participants

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT and KarXT + KarX-EC in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-07-11
Completion: 2027-09-07
Conditions
Psychosis Associated With Alzheimer's Disease
Interventions
DRUG
No Results Yet
NCT05978128 | RECRUITING | NA
800 Participants

Utilizing Advocates and Supporters to Increase Lung Cancer Screening Rates in Eligible Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-07-28
Completion: 2028-09-30
Conditions
Breast Carcinoma Lung Carcinoma
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT05972109 | ACTIVE_NOT_RECRUITING | NA
700 Participants

Metabolic Health Improvement Program: Effects of a Workplace Sugary Beverages Sales Ban and Motivational Counseling

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-08-01
Completion: 2025-10-01
Conditions
Obesity, Abdominal Insulin Sensitivity
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT05963074 | RECRUITING | PHASE2
320 Participants

A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-30
Completion: 2025-11-15
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell Small Lymphocytic Lymphoma
Interventions
DRUG
No Results Yet
NCT05957276 | ACTIVE_NOT_RECRUITING
892 Participants

Global Patient Registry of Inherited Retinal Diseases

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2023-08-31
Completion: 2026-07-03
Conditions
Inherited Retinal Diseases
Interventions
OTHER
No Results Yet
NCT05948566 | RECRUITING | PHASE2
300 Participants

Strategy for Improving Stroke Treatment Response

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-03-18
Completion: 2027-07-31
Conditions
Ischemic Stroke
Interventions
BIOLOGICAL
No Results Yet
NCT05947838 | RECRUITING | NA
48 Participants

A Prospective Feasibility Study Using ctDNA to Tailor Neoadjuvant Chemotherapy for Patients With Colorectal or Appendiceal Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-12-04
Completion: 2026-04-30
Conditions
Appendiceal Adenocarcinoma Colorectal
Interventions
PROCEDURE
No Results Yet
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