Clinical Trials

NCT05247866 | COMPLETED | PHASE4

21 Participants

Efficacy of Dupilumab on Facilitated Food Introduction in Eosinophilic Esophagitis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-06-16

Completion: 2025-01-21

Conditions

Eosinophilic Esophagitis

Interventions

DIETARY_SUPPLEMENT DRUG

Results Available

NCT05246839 | TERMINATED

1823 Participants

Informed Choice - Compass

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2022-04-28

Completion: 2025-01-31

Conditions

Colorectal Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05245786 | RECRUITING | EARLY_PHASE1

15 Participants

An Investigational Scan (64Cu-Labeled M5A Antibody) in Combination With SOC Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-08-31

Completion: 2026-11-12

Conditions

Locally Advanced Rectal Carcinoma Stage III Rectal Cancer AJCC v8 Stage IIIA Rectal Cancer AJCC v8 Stage IIIB Rectal Cancer AJCC v8 Stage IIIC Rectal Cancer AJCC v8

Interventions

BIOLOGICAL PROCEDURE

No Results Yet

NCT05245500 | RECRUITING | PHASE1

336 Participants

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-06-09

Completion: 2027-12-10

Conditions

Mesothelioma Non Small Cell Lung Cancer Malignant Peripheral Nerve Sheath Tumors Solid Tumor Pancreatic Adenocarcinoma Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT05242484 | ACTIVE_NOT_RECRUITING | PHASE2

577 Participants

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-09-19

Completion: 2025-05-15

Conditions

Colitis, Ulcerative

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT05242471 | ACTIVE_NOT_RECRUITING | PHASE2

703 Participants

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-07-22

Completion: 2025-05-23

Conditions

Crohn's Disease

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT05237128 | COMPLETED | NA

182 Participants

The Lifestyle Education About Nutrition for Diabetes (Legend) Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-03-22

Completion: 2025-10-01

Conditions

Type 2 Diabetes

Interventions

BEHAVIORAL

No Results Yet

NCT05235425 | ACTIVE_NOT_RECRUITING | NA

300 Participants

The Lifestyle Education About Prediabetes (Leap) Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-03-20

Completion: 2025-11-15

Conditions

PreDiabetes

Interventions

BEHAVIORAL

No Results Yet

NCT05232110 | APPROVED_FOR_MARKETING

Compassionate Use of Pozelimab

Study Type: EXPANDED_ACCESS

Last Updated: 2025-11-10

Conditions

CD55-deficient Protein-losing Enteropathy

Interventions

DRUG

No Results Yet

NCT05223803 | RECRUITING | PHASE2

122 Participants

TERPS Trial for de Novo Oligometastic Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-10-18

Completion: 2026-07-31

Conditions

Prostate Cancer Oligometastatic Disease

Interventions

RADIATION DRUG

No Results Yet

NCT05223036 | SUSPENDED | PHASE2

80 Participants

Testing Obeticholic Acid for Familial Adenomatous Polyposis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-01-19

Completion: 2029-01-31

Conditions

Attenuated Familial Adenomatous Polyposis Colorectal Carcinoma Duodenal Carcinoma Familial Adenomatous Polyposis

Interventions

PROCEDURE BIOLOGICAL DRUG OTHER

No Results Yet

NCT05220501 | COMPLETED | NA

804 Participants

Optimization of Prostate Biopsy - Micro-Ultrasound Versus MRI

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-12-15

Completion: 2024-09-06

Conditions

Prostate Cancer

Interventions

DIAGNOSTIC_TEST

Results Available

NCT05213572 | RECRUITING

200 Participants

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2022-03-24

Completion: 2035-06-01

Conditions

Mortality in Sickle Cell Sickle Cell Cardiopulmonary Complications Sickle Cell Organ Damage Sickle Cell Life Expectancy and Risk Factors for Early Death Sickle Cell Lung Disease and Sudden Death

No Results Yet

NCT05206929 | TERMINATED | NA

10 Participants

Prescribed Sternal Precautions vs. Self-Guided Restrictive Care (PEEERC)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-06-01

Completion: 2022-11-21

Conditions

Surgery Heart Diseases Heart Failure Cardiac Valve Disease

Interventions

OTHER

No Results Yet

NCT05201781 | RECRUITING | PHASE4

295 Participants

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-03-09

Completion: 2037-07-29

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05199870 | NOT_YET_RECRUITING

116 Participants

MDR - PMCF Study for RingLoc Bipolar Acetabular Cup and Endo II Femoral Heads

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2025-11-30

Completion: 2030-09-03

Conditions

Hip Arthritis Hip Disease Hip Fractures Hip Injuries Hip Pain Chronic

Interventions

DEVICE

No Results Yet

NCT05198830 | RECRUITING | PHASE2

42 Participants

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-12-15

Completion: 2027-06-30

Conditions

Lung Adenocarcinoma Lung Large Cell Carcinoma Lung Non-Squamous Non-Small Cell Carcinoma Stage III Lung Cancer AJCC v8

Interventions

DRUG PROCEDURE BIOLOGICAL RADIATION

No Results Yet

NCT05198765 | ACTIVE_NOT_RECRUITING | NA

10120 Participants

Weight Loss Clinical Decision Support

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-04-19

Completion: 2025-10-31

Conditions

Diabetes Mellitus, Type 2 Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT05195710 | RECRUITING | PHASE1

50 Participants

Preoperative Y-90 Radioembolization for Tumor Control and Future Liver Remnant Hypertrophy in Patients With Colorectal Liver Metastases

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-11-16

Completion: 2026-03-31

Conditions

Metastases

Interventions

DRUG

No Results Yet

NCT05194735 | TERMINATED | PHASE1/PHASE2

8 Participants

Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-04-04

Completion: 2023-08-14

Conditions

Gynecologic Cancer Colorectal Cancer Pancreatic Cancer Non-small Cell Lung Cancer Cholangiocarcinoma Ovarian Cancer Endometrial Cancer Ovarian Carcinoma Ovary Neoplasm Squamous Cell Lung Cancer Adenocarcinoma of Lung Adenosquamous Cell Lung Cancer

Interventions

BIOLOGICAL

Results Available

NCT05185089 | COMPLETED | PHASE2

80 Participants

Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-08-01

Completion: 2024-06-05

Conditions

Cough Idiopathic Pulmonary Fibrosis

Interventions

DRUG

Results Available

NCT05172245 | RECRUITING | PHASE1

46 Participants

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-09-19

Completion: 2026-06-01

Conditions

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Head and Neck Carcinoma of Unknown Primary Locally Advanced Head and Neck Squamous Cell Carcinoma Locally Advanced Hypopharyngeal Squamous Cell Carcinoma Locally Advanced Laryngeal Squamous Cell Carcinoma Locally Advanced Nasal Cavity Squamous Cell Carcinoma Locally Advanced Oral Cavity Squamous Cell Carcinoma Locally Advanced Oropharyngeal Squamous Cell Carcinoma Locally Advanced Paranasal Sinus Squamous Cell Carcinoma Locally Advanced Sinonasal Squamous Cell Carcinoma Maxillary Sinus Squamous Cell Carcinoma Stage III Hypopharyngeal Carcinoma AJCC v8 Stage III Laryngeal Cancer AJCC v8 Stage III Lip and Oral Cavity Cancer AJCC v8 Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 Stage III Sinonasal Cancer AJCC v8 Stage IVA Hypopharyngeal Carcinoma AJCC v8 Stage IVA Laryngeal Cancer AJCC v8 Stage IVA Lip and Oral Cavity Cancer AJCC v8 Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8 Stage IVA Sinonasal Cancer AJCC v8 Stage IVB Hypopharyngeal Carcinoma AJCC v8 Stage IVB Laryngeal Cancer AJCC v8 Stage IVB Lip and Oral Cavity Cancer AJCC v8 Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8 Stage IVB Sinonasal Cancer AJCC v8

Interventions

PROCEDURE DRUG RADIATION

No Results Yet

NCT05171894 | RECRUITING | PHASE2

84 Participants

A Study to Evaluate Efficacy and Safety of Light Dose in Subjects With PWB Treated With Hemoporfin PDT

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-09-21

Completion: 2027-01-31

Conditions

Port-wine Birthmarks Port-Wine Stain Nevus Flammeus

Interventions

DRUG DEVICE

No Results Yet

NCT05164250 | APPROVED_FOR_MARKETING

Compassionate Use (CU) of REGN5458 for Patients With Relapsed or Refractory Multiple Myeloma (MM)

Study Type: EXPANDED_ACCESS

Last Updated: 2025-11-10

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05160584 | RECRUITING

300 Participants

A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2021-11-18

Completion: 2028-04-30

Conditions

Relapsed/Refractory Multiple Myeloma

Interventions

OTHER

No Results Yet

NCT05146167 | COMPLETED | NA

107 Participants

Feasibility Testing a Meditation App for Youth in the Legal System

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-04-05

Completion: 2025-10-15

Conditions

Behavioral Health

Interventions

BEHAVIORAL

No Results Yet

NCT05141682 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

11 Participants

Oral Azacitidine for the Treatment of Relapsed or Refractory T-cell Large Granular Lymphocytic Leukemia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-06-29

Completion: 2026-01-15

Conditions

T-Cell Large Granular Lymphocyte Leukemia

Interventions

DRUG

No Results Yet

NCT05139017 | RECRUITING | PHASE2/PHASE3

290 Participants

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-01-14

Completion: 2027-09-24

Conditions

DLBCL Diffuse Large B-Cell Lymphoma

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT05136196 | RECRUITING | PHASE2

150 Participants

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-12-06

Completion: 2027-01-01

Conditions

Clinical Stage III Cutaneous Melanoma AJCC v8 Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Clinical Stage IV Cutaneous Melanoma AJCC v8 Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Locally Recurrent Head and Neck Squamous Cell Carcinoma Locally Recurrent Hypopharyngeal Squamous Cell Carcinoma Locally Recurrent Laryngeal Squamous Cell Carcinoma Locally Recurrent Oral Cavity Squamous Cell Carcinoma Locally Recurrent Oropharyngeal Squamous Cell Carcinoma Metastatic Head and Neck Squamous Cell Carcinoma Metastatic Hypopharyngeal Squamous Cell Carcinoma Metastatic Laryngeal Squamous Cell Carcinoma Metastatic Melanoma Metastatic Oral Cavity Squamous Cell Carcinoma Metastatic Oropharyngeal Squamous Cell Carcinoma Recurrent Melanoma Stage III Hypopharyngeal Carcinoma AJCC v8 Stage III Laryngeal Cancer AJCC v8 Stage III Lip and Oral Cavity Cancer AJCC v8 Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 Stage IV Hypopharyngeal Carcinoma AJCC v8 Stage IV Laryngeal Cancer AJCC v8 Stage IV Lip and Oral Cavity Cancer AJCC v8 Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8 Unresectable Melanoma

Interventions

PROCEDURE DRUG BIOLOGICAL

No Results Yet

NCT05132075 | ACTIVE_NOT_RECRUITING | PHASE3

95 Participants

Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-06-15

Completion: 2026-02-28

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05126901 | COMPLETED | PHASE3

65 Participants

Evaluate the Safety and Efficacy of Ferric Maltol Oral Suspension vs. Ferrous Sulfate Oral Liquid in Children and Adolescents Aged 2 to 17 Years With Iron-deficiency Anaemia, With a Single Arm Study in Infants Aged 1 Month to Less Than 2 Years

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-11-03

Completion: 2024-06-09

Conditions

Anemia Iron-deficiency

Interventions

DRUG

Results Available

NCT05124405 | ACTIVE_NOT_RECRUITING | NA

35 Participants

Monitoring Your Exercise-related Metrics Over Time Via Wearable Electronic Devices

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-05-24

Completion: 2027-01-31

Conditions

Cancer Diabetes

Interventions

OTHER

No Results Yet

NCT05119569 | ACTIVE_NOT_RECRUITING | PHASE2

109 Participants

A Study to Investigate the Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (RMS)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-03-01

Completion: 2023-03-29

Conditions

Relapsing Multiple Sclerosis

Interventions

DRUG

Results Available

NCT05111574 | RECRUITING | PHASE2

99 Participants

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-08-11

Completion: 2025-12-19

Conditions

Anal Melanoma Bladder Melanoma Cervical Melanoma Esophageal Melanoma Gallbladder Melanoma Head and Neck Mucosal Melanoma Mucosal Melanoma Nasopharyngeal Mucosal Melanoma Oral Cavity Mucosal Melanoma Penile Mucosal Melanoma Rectal Melanoma Recurrent Mucosal Melanoma Sinonasal Mucosal Melanoma Urethral Melanoma Urinary System Mucosal Melanoma Vaginal Melanoma Vulvar Melanoma

Interventions

PROCEDURE DRUG BIOLOGICAL

No Results Yet

NCT05110742 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

11 Participants

Phase I/II Study of CD5 CAR Engineered IL15-Transduced Cord Blood-Derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Hematological Malignances

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-04-22

Completion: 2027-12-30

Conditions

Hematological Malignancy

Interventions

DRUG

No Results Yet

NCT05100862 | RECRUITING | PHASE3

780 Participants

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-03-10

Completion: 2028-07-31

Conditions

Relapsed/Refractory Follicular Lymphoma Marginal Zone Lymphoma

Interventions

DRUG

No Results Yet

NCT05092516 | ACTIVE_NOT_RECRUITING | NA

40 Participants

Home-based Brain Stimulation Treatment for Post-acute Sequelae of COVID-19 (PASC)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-06-07

Completion: 2025-03-13

Conditions

Dysexecutive Syndrome Post-Acute Sequelae of COVID-19

Interventions

DEVICE

No Results Yet

NCT05092269 | RECRUITING | PHASE3

151 Participants

A Long-term Extension Study of Ustekinumab in Pediatric Participants

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-10-18

Completion: 2027-09-29

Conditions

Crohn Disease Colitis, Ulcerative Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT05091710 | COMPLETED | NA

30 Participants

Haiti Community Health Workers (CHW) Adaptation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-02-23

Completion: 2025-08-31

Conditions

Heart Failure

Interventions

OTHER

No Results Yet

NCT05091424 | RECRUITING | PHASE1

137 Participants

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-03-07

Completion: 2028-05-31

Conditions

Chronic Lymphocytic Leukemia

Interventions

DRUG

No Results Yet