Clinical Trials

NCT06814522 | RECRUITING | PHASE1/PHASE2
10 Participants

Psilocybin-Assisted Therapy for Physician Well-Being and Burnout

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2025-12-31
Completion: 2026-06-30
Conditions
Burnout Burnout, Healthcare Workers
Interventions
DRUG
No Results Yet
NCT06810544 | RECRUITING | PHASE1/PHASE2
191 Participants

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2025-03-24
Completion: 2027-03-31
Conditions
Non Small Cell Lung Cancer Glioma Glioblastoma Multiforme Glioma, Malignant Solid Tumor Non-Small Cell Adenocarcinoma Lung Cancer Brain Tumor
Interventions
DRUG
No Results Yet
NCT06809803 | RECRUITING | PHASE2
36 Participants

Extended-release Sodium Oxybate in Children

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2025-10-27
Completion: 2027-06-30
Conditions
Narcolepsy Type 1 (NT 1)
Interventions
DRUG
No Results Yet
NCT06789406 | RECRUITING | NA
55 Participants

PMCF Study of the Axonics SNM System Model 5101 (R20)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2025-09-18
Completion: 2027-01-31
Conditions
Urinary Urge Incontinence (UUI) Urinary Frequency (UF) Overactive Bladder (OAB)
Interventions
DEVICE
No Results Yet
NCT06773910 | RECRUITING | PHASE2
250 Participants

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2025-03-11
Completion: 2032-05-31
Conditions
Limited Stage Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06754462 | RECRUITING | PHASE2
120 Participants

A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2025-01-10
Completion: 2027-09-30
Conditions
Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
NCT06744647 | RECRUITING | PHASE2
45 Participants

Phase 2 Study of ALXN2030 in Patients With Antibody-Mediated Rejection After Kidney Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2025-03-07
Completion: 2027-10-11
Conditions
Antibody-Mediated Rejection Kidney Transplantation Biopsy-proven Histologic Scores AMR
Interventions
DRUG
No Results Yet
NCT06731907 | RECRUITING | PHASE2
90 Participants

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2025-03-30
Completion: 2032-03-12
Conditions
Non-small Cell Lung Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06724822 | ACTIVE_NOT_RECRUITING | NA
12 Participants

RF Vapor Ablation Retreatment of Duodenal Mucosa in Non-responders With Type-2 Diabetes Mellitus

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-11-14
Completion: 2027-06-30
Conditions
Diabetes Mellitus, Type 2
Interventions
DEVICE
No Results Yet
NCT06724614 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
480 Participants

Efficacy and Safety of VDPHL01 in Males With AGA

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-11-06
Completion: 2026-02-28
Conditions
Androgenetic Alopecia AGA Male Pattern Baldness
Interventions
DRUG
No Results Yet
NCT06721351 | ACTIVE_NOT_RECRUITING | NA
548 Participants

Diabetic Retinopathy Screening Point-of-Care Artificial Intelligence

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-07-27
Completion: 2025-12-31
Conditions
Diabetic Retinopathy (DR)
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06703190 | TERMINATED
1 Participants

Estimated Vaccine Effectiveness and Durability of Pfizer/BioNTech 2024-2025 COVID-19 Vaccine

Study Type: OBSERVATIONAL
Last Updated: 2025-11-06
Start Date: 2024-11-25
Completion: 2025-06-06
Conditions
COVID-19
Interventions
BIOLOGICAL
No Results Yet
NCT06701526 | RECRUITING | PHASE4
150 Participants

A Trial of Eptinezumab in Participants With Migraine and Insufficient Response to Anti-CGRP Medications

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-12-18
Completion: 2026-06-05
Conditions
Migraine
Interventions
DRUG
No Results Yet
NCT06698250 | RECRUITING | PHASE2
40 Participants

Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-12-18
Completion: 2026-12-31
Conditions
Hepatocellular Carcinoma
Interventions
DRUG
No Results Yet
NCT06695156 | ACTIVE_NOT_RECRUITING | NA
30 Participants

Exploring the Effect of the Transcendental Meditationยฎ Technique on Migraine Frequency and Functionality: A Single Arm Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-08-28
Completion: 2026-04-30
Conditions
Migraine Migraine With or Without Aura
Interventions
BEHAVIORAL
No Results Yet
NCT06649110 | RECRUITING | PHASE1/PHASE2
232 Participants

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-10-24
Completion: 2028-11-29
Conditions
Healthy Volunteers, Pulmonary Arterial Hypertension
Interventions
DRUG
No Results Yet
NCT06639854 | RECRUITING | NA
105 Participants

The Use of Cytomegalovirus Cell Mediated Immunity to Optimize the Duration of Letermovir Prophylaxis in Hematopoietic Cell Transplant Recipients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-11-20
Completion: 2026-12-31
Conditions
Cytomegalovirus Cell Mediated Immunity Hematopoietic Cell Transplant
Interventions
PROCEDURE DRUG
No Results Yet
NCT06637371 | RECRUITING | PHASE1
124 Participants

A Phase 1, Randomized, Double-blind, Placebo-controlled Study Evaluating AMG 691 in Healthy Participants and Participants With Mild-to-Moderate Asthma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-10-16
Completion: 2027-06-07
Conditions
Asthma
Interventions
DRUG
No Results Yet
NCT06624163 | ACTIVE_NOT_RECRUITING | NA
19 Participants

Evaluation of Patient Coach Support for Older Adults With Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-06-08
Completion: 2025-09-30
Conditions
Obesity
Interventions
BEHAVIORAL
No Results Yet
NCT06617429 | ACTIVE_NOT_RECRUITING | PHASE3
129 Participants

Phase 3 Efficacy and Safety Study of GTX-102 in Pediatric Subjects With Angelman Syndrome (AS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-12-03
Completion: 2026-07-31
Conditions
Angelman Syndrome
Interventions
PROCEDURE DRUG
No Results Yet
NCT06605807 | NOT_YET_RECRUITING | NA
150 Participants

Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2025-11-30
Completion: 2026-03-31
Conditions
Prescribing Decisions Diabetes Multimorbidity Hypertension Geriatrics
Interventions
OTHER
No Results Yet
NCT06599502 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
17 Participants

A Phase I/IIa Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD0022 as Monotherapy and in Combination With Anti-cancer Agents in Adult Participants With Tumours Harbouring a KRASG12D Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-10-18
Completion: 2025-10-20
Conditions
Advanced Solid Tumours Non-Small Cell Lung Cancer (NSCLC) Pancreatic Ductal Adenocarcinoma (PDAC) Colorectal Cancer (CRC)
Interventions
DRUG
No Results Yet
NCT06598943 | RECRUITING | PHASE2
140 Participants

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-10-10
Completion: 2027-12-31
Conditions
Ulcerative Colitis Ulcerative Colitis Chronic
Interventions
DRUG
No Results Yet
NCT06585410 | RECRUITING | PHASE3
369 Participants

Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2025-01-02
Completion: 2030-05-03
Conditions
Cutaneous Squamous Cell Carcinoma (CSCC)
Interventions
DRUG PROCEDURE
No Results Yet
NCT06581211 | SUSPENDED | NA
45 Participants

Aromatherapy Oil Associated for Managing Anxiety and Pain During Bone Marrow Biopsy Procedures

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-08-23
Completion: 2026-06-25
Conditions
Hematopoietic and Lymphatic System Neoplasm Malignant Solid Neoplasm
Interventions
PROCEDURE OTHER
No Results Yet
NCT06576635 | RECRUITING | NA
29 Participants

LUNG-05: Investigating Chemotherapy Effectiveness for Non-Small Cell Lung Cancer (NSCLC) Metastatic Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-12-16
Completion: 2026-09-30
Conditions
NSCLC
Interventions
DRUG
No Results Yet
NCT06569823 | RECRUITING | PHASE1/PHASE2
764 Participants

Safety and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrixยฎ in Healthy Adults 50 Years of Age and Over

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-06-17
Completion: 2027-11-30
Conditions
Shingles Herpes Zoster Vaccine-Preventable Diseases
Interventions
BIOLOGICAL
No Results Yet
NCT06564142 | RECRUITING | PHASE3
480 Participants

Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-08-30
Completion: 2028-09-30
Conditions
Immunoglobulin A Nephropathy
Interventions
DRUG
No Results Yet
NCT06561685 | RECRUITING | PHASE1
340 Participants

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-09-19
Completion: 2027-10-31
Conditions
Metastatic Solid Tumor Advanced Solid Tumor Non-small Cell Lung Cancer SMARCA4-Deficient Tumor
Interventions
DRUG
No Results Yet
NCT06560021 | ENROLLING_BY_INVITATION | NA
1642 Participants

Utility of Random Biopsies in Patients With Inflammatory Bowel Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-12-11
Completion: 2028-12-31
Conditions
Inflammatory Bowel Diseases Crohn Disease Ulcerative Colitis
Interventions
OTHER
No Results Yet
NCT06548087 | COMPLETED | NA
44 Participants

Use Of Gigstride Device In Patients With Lower Extremity Deficit

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-10-08
Completion: 2025-08-26
Conditions
Ambulation Difficulty Lower Extremity Problem
Interventions
DEVICE
No Results Yet
NCT06546956 | RECRUITING | PHASE1/PHASE2
30 Participants

Integrative Breathwork Intervention for Chronic Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-10-24
Completion: 2026-12-22
Conditions
Chronic Low-back Pain
Interventions
BEHAVIORAL
No Results Yet
NCT06546553 | TERMINATED | PHASE1
9 Participants

A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-09-06
Completion: 2025-10-03
Conditions
Neoplasms Non-small-cell Lung Cancer Squamous Cell Carcinoma of the Head and Neck Renal Cell Carcinoma Colorectal Carcinoma Ovarian Carcinoma
Interventions
DRUG BIOLOGICAL OTHER
No Results Yet
NCT06541704 | RECRUITING | PHASE3
975 Participants

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-10-30
Completion: 2027-11-29
Conditions
Age-related Macular Degeneration (AMD) Geographic Atrophy (GA)
Interventions
DRUG
No Results Yet
NCT06538116 | RECRUITING | PHASE2
300 Participants

A Study of Mevidalen (LY3154207) in Participants With Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-08-26
Completion: 2025-12-31
Conditions
Alzheimer Disease
Interventions
DRUG
No Results Yet
NCT06529679 | RECRUITING | NA
30 Participants

Michigan Split-belt Treadmill Training Program to Improve Acute Knee Biomechanics After ACL Reconstruction

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-10-29
Completion: 2025-12-31
Conditions
ACL ACL Injury
Interventions
BEHAVIORAL
No Results Yet
NCT06527365 | ACTIVE_NOT_RECRUITING | PHASE2
70 Participants

Safety and Efficacy of VDPHL01 in Males and Females With AGA

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-07-08
Completion: 2026-08-31
Conditions
Androgenetic Alopecia AGA Male Pattern Baldness
Interventions
DRUG
No Results Yet
NCT06511141 | RECRUITING | NA
150 Participants

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-10-22
Completion: 2027-12-31
Conditions
Overactive Bladder Urinary Urgency Incontinence Benign Prostatic Hyperplasia Prostate Cancer Prostatectomy Urinary Frequency
Interventions
DEVICE
No Results Yet
NCT06510816 | ACTIVE_NOT_RECRUITING | PHASE3
659 Participants

A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of Vonaprument (Formerly ANX007) in Participants With Geographic Atrophy (GA)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-07-30
Completion: 2026-10-31
Conditions
Geographic Atrophy
Interventions
DRUG OTHER
No Results Yet
NCT06504368 | RECRUITING | PHASE1
32 Participants

Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-05-29
Completion: 2026-06-01
Conditions
Solid Tumors, Adult
Interventions
DRUG
No Results Yet
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