Clinical Trials

Showing trials with last updates posted in 2024.

NCT06197178 | RECRUITING | PHASE1
42 Participants

A Study of LCAR-G08 in Subjects With Advanced Gastrointestinal Tumors Expressing Guanylyl Cyclase C (GCC)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-12-28
Completion: 2025-11-30
Conditions
Advanced Gastrointestinal Tumors
Interventions
BIOLOGICAL
No Results Yet
NCT06176963 | COMPLETED | PHASE2
34 Participants

A Study to Evaluate the Usability of the SB11 PFS in Subjects With Wet AMD or Macular Oedema Secondary to RVO

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-11-21
Completion: 2023-11-30
Conditions
Neovascular Age-related Macular Degeneration Macular Edema Retinal Vein Occlusion
Interventions
COMBINATION_PRODUCT
NCT06166381 | RECRUITING | NA
288 Participants

Parenteral Versus Combined Parenteral With Vancomycin-soaked Graft in ACL Reconstruction

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2024-01-25
Completion: 2024-12-31
Conditions
Infection, Bacterial
Interventions
DRUG
No Results Yet
NCT06158607 | RECRUITING | NA
60 Participants

Pre-exposure Prophylaxis (PrEP) Adherence Intervention for Women with Substance Use Disorders

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2022-06-07
Completion: 2025-05-30
Conditions
Substance Use
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06098157 | RECRUITING
850 Participants

Tuebingen Register of Union Failure After Fractures of the Upper and Lower Extremities

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2020-01-01
Completion: 2025-12-31
Conditions
Pseudarthrosis Ununited Fracture
No Results Yet
NCT06084338 | RECRUITING | PHASE2
60 Participants

Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-12-14
Completion: 2027-11-29
Conditions
Prostate Cancer
Interventions
RADIATION DRUG
No Results Yet
NCT06073301 | ACTIVE_NOT_RECRUITING | PHASE4
30 Participants

AFS Compared to AHC in Treatment of Necrotizing Fasciitis NF

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-08-01
Completion: 2025-08-01
Conditions
Necrotizing Fasciitis
Interventions
DEVICE OTHER
No Results Yet
NCT06069713 | COMPLETED | NA
3504 Participants

Consumer Perceptions of Cannabidiol (CBD) Health Claims

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-10-09
Completion: 2023-11-20
Conditions
Perceptions
Interventions
BEHAVIORAL
NCT06054906 | RECRUITING | PHASE2
50 Participants

Neoadjuvant of Sintilimab Combined Weekly Metronomic Chemotherapy (PLOF) for Resectable Locally Advanced Gastric Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-10-18
Completion: 2025-06-30
Conditions
Gastric Cancer
Interventions
DRUG
No Results Yet
NCT06048783 | NOT_YET_RECRUITING | NA
30 Participants

Feasibility and Preliminary Effects of a Spiritual Care Strategy on Psychological Disorders in Critically Ill Patients

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2025-01-15
Completion: 2025-06-30
Conditions
Psychological Disorder Critical Illness
Interventions
BEHAVIORAL
No Results Yet
NCT06028854 | SUSPENDED
40 Participants

Blood Characteristics and Abdominal Emergency Surgery

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2025-10-15
Completion: 2027-10-15
Conditions
Surgical Wound
No Results Yet
NCT05969886 | COMPLETED
405 Participants

Ventricular-Arterial Coupling: A Predictor of Post-Induction Hypotension

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2023-07-03
Completion: 2024-11-20
Conditions
Hypotension on Induction
No Results Yet
NCT05958719 | RECRUITING | PHASE2
37 Participants

Chidamide in Combination With Azacitidine, Liposomal Mitoxantrone, and Prednisone (CAMP Regimen) for the Treatment of Previously Untreated Nodal TFH Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-03-02
Completion: 2026-12-30
Conditions
Peripheral T Cell Lymphoma Epigenetic Repression
Interventions
DRUG
No Results Yet
NCT05939830 | RECRUITING | NA
92 Participants

Omission of ALND in Breast Cancer Patients With Axillary pCR

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-09-11
Completion: 2025-07-31
Conditions
Axillary Lymph Node Dissection Pathological Complete Response Neoadjuvant Systemic Therapy Breast Cancer Axillary Lymph
Interventions
PROCEDURE RADIATION
No Results Yet
NCT05922345 | RECRUITING | PHASE3
518 Participants

Evaluation of the Efficacy and Safety of AL2846 Capsule Combined With TQB2450 Injection Compared to Docetaxel Injection in Advanced Non-small Cell Lung Cancer Patients Who Have Failed With Immunotherapy.

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-06-08
Completion: 2025-08-31
Conditions
Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT05904730 | COMPLETED | PHASE1
10 Participants

Phase I Clinical Trials Investigating the Potential Efficacy of Axitinib in Patients With a BRCA 1/2 Mutations

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-07-11
Completion: 2024-11-09
Conditions
Breast Cancer Ovarian Cancer Breast Neoplasms Ovarian Neoplasms BRCA Mutation HER2-positive Breast Cancer HER2-negative Breast Cancer HER-2 Protein Overexpression
Interventions
DRUG
No Results Yet
NCT05901051 | COMPLETED | PHASE4
327 Participants

High-dose Dual Therapy with Different Administration Frequencies

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2021-03-30
Completion: 2023-09-10
Conditions
Helicobacter Pylori Infection
Interventions
DRUG
No Results Yet
NCT05898698 | ACTIVE_NOT_RECRUITING
300 Participants

Prospective Case Registry for Wounds

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2023-03-17
Completion: 2025-03-17
Conditions
Wound Healing Delayed
No Results Yet
NCT05874570 | RECRUITING | PHASE4
368 Participants

Doxycycline for Helicobacter Pylori Rescue Treatment

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-06-20
Completion: 2025-10-10
Conditions
Helicobacter Pylori Infection
Interventions
DRUG
No Results Yet
NCT05871905 | COMPLETED | PHASE1
6 Participants

[14 C] Study on Mass Balance of TY-9591 in Healthy Chinese Subjects

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-06-19
Completion: 2023-11-06
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT05869227 | ACTIVE_NOT_RECRUITING | PHASE3
166 Participants

Maintenance Therapy With Toripalimab Combined With Capecitabine/Placebo for Recurrent and Metastatic Nasopharyngeal Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-04-28
Completion: 2027-12-20
Conditions
Nasopharyngeal Carcinoma Maintenance Therapy
Interventions
DRUG
No Results Yet
NCT05847855 | RECRUITING
440 Participants

Multi-dimensional Fragmentomic Assay for Early Detection of Pancreatic Neuroendocrine Tumors

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2023-02-27
Completion: 2025-12-31
Conditions
Pancreatic Neuroendocrine Tumor
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05833867 | RECRUITING | PHASE1
20 Participants

Adaptive RADiation Therapy with Concurrent Sacituzumab Govitecan (SG) for Muscle Invasive Bladder Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2024-04-01
Completion: 2025-12-31
Conditions
Localized Muscle Invasive Bladder Urothelial Carcinoma Muscle-Invasive Bladder Carcinoma
Interventions
DRUG RADIATION
No Results Yet
NCT05788848 | COMPLETED | PHASE1
36 Participants

Virtual Reality Cognitive Therapy for Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-03-31
Completion: 2024-08-20
Conditions
Alzheimer Disease
Interventions
BEHAVIORAL
No Results Yet
NCT05784584 | COMPLETED
220 Participants

Early Anti-Retroviral Treatment in HIV- Infected Children

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2018-05-01
Completion: 2024-02-28
Conditions
HIV Infections
Interventions
PROCEDURE
No Results Yet
NCT05760794 | ACTIVE_NOT_RECRUITING | NA
52 Participants

Barbed-suture Efficiency Study for Sacrocolpopexy

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-06-21
Completion: 2026-12-31
Conditions
Prolapse; Female
Interventions
PROCEDURE
No Results Yet
NCT05712902 | ACTIVE_NOT_RECRUITING | PHASE2
104 Participants

Sunvozertinib (DZD9008) in Pretreated Lung Cancer Patients with EGFR Exon20 Insertion Mutation (WU-KONG6)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2021-07-19
Completion: 2022-10-17
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT05709249 | RECRUITING | PHASE3
730 Participants

Xian-Lian-Jie-Du Optimization Decoction As an Adjuvant Treatment for Prevention of Recurrence of Colon Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2022-12-01
Completion: 2027-04-01
Conditions
Colon Cancer
Interventions
DRUG
No Results Yet
NCT05681962 | RECRUITING
10000 Participants

Practice of Oxygenation and Respiratory Support During Fiberoptic Bronchoscopy

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2023-02-15
Completion: 2025-12-31
Conditions
Acute Respiratory Failure Pneumonia Lung Cancer Fibrosis Lung Interstitial Lung Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05634135 | RECRUITING
103 Participants

Lung Ventilation and Perfusion in Different Phenotypes of Chronic Critical Illness With Prolonged Mechanical Ventilation

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2022-07-31
Completion: 2025-02-17
Conditions
Prolonged Mechanical Ventilation
No Results Yet
NCT05584930 | COMPLETED | NA
55 Participants

Clusterin, Ptx3 and Pediatric Febrile Neutropenia (CluPPFeN)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2022-10-10
Completion: 2024-06-13
Conditions
Cancer Childhood Febrile Neutropenia
Interventions
OTHER
No Results Yet
NCT05577234 | COMPLETED | NA
50 Participants

Contribution of Animal-assisted Intervention in Oral Healthcare for Disabled Patients (YODA)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-03-24
Completion: 2024-03-25
Conditions
Autism
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT05552014 | RECRUITING | NA
80 Participants

Study on the Efficacy Mechanism of Natural Psychotherapy for Neurosis

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2022-05-01
Completion: 2025-12-01
Conditions
Obsessive-Compulsive Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT05532241 | RECRUITING | PHASE3
80 Participants

Dental Biofilm Control During Orthodontic Treatment

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2021-11-01
Completion: 2025-05-01
Conditions
Gingivitis Malocclusion
Interventions
DEVICE PROCEDURE DRUG
No Results Yet
NCT05525702 | RECRUITING | NA
102 Participants

VR Interventions to Reduce the Prevalence of Delirium in ICU Patients

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-12-18
Completion: 2026-12-31
Conditions
Delirium
Interventions
DEVICE
No Results Yet
NCT05499637 | RECRUITING | PHASE2
69 Participants

[68Ga]Ga-PentixaFor PET/CT in Acute Myocardial Inflammation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-01-17
Completion: 2025-12-31
Conditions
Acute Cellular Graft Rejection Cardiac Sarcoidosis Myocarditis Due to Drug
Interventions
DRUG
No Results Yet
NCT05493787 | COMPLETED | NA
139503 Participants

Nudging Flu Vaccination by Making it Easy for Patients to Schedule a Flu Shot

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2022-11-08
Completion: 2023-01-03
Conditions
Influenza
Interventions
BEHAVIORAL
NCT05492838 | COMPLETED | NA
12 Participants

Socket Shield Technique With or Without Flap Elevation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2019-07-18
Completion: 2023-12-21
Conditions
Alveolar Bone Resorption
Interventions
PROCEDURE
No Results Yet
NCT05492786 | COMPLETED | NA
80452 Participants

High-risk Influenza Vaccine Alert

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2022-09-01
Completion: 2023-04-01
Conditions
Influenza
Interventions
BEHAVIORAL
NCT05421429 | COMPLETED | PHASE2
24 Participants

KN057 Multiple Dose Study in Moderately Severe to Severe Hemophilia

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2022-07-07
Completion: 2024-01-17
Conditions
Hemophilia
Interventions
BIOLOGICAL
No Results Yet
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