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Clinical Trials

Showing trials with last updates posted in 2024.

NCT04297683 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
1500 Participants

HEALEY ALS Platform Trial - Master Protocol

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2020-07-14
Completion: 2025-07-31
Conditions
Amyotrophic Lateral Sclerosis
Interventions
DRUG
No Results Yet
NCT04271956 | RECRUITING | PHASE2
83 Participants

Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment with or Without Sonrotoclax for Patients with Richter Transformation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2020-02-19
Completion: 2026-08-31
Conditions
Richter Transformation
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT04260230 | WITHDRAWN | NA
0 Participants

Remote Monitoring of Patients at Risk of Sepsis

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2022-03-31
Completion: 2022-10-31
Conditions
Neutropenia, Febrile Cancer Sepsis
Interventions
DEVICE
No Results Yet
NCT04221451 | TERMINATED | PHASE3
75 Participants

A Multinational, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Pharmacodynamics, Pharmacokinetics, and Safety of Venglustat in Late-onset GM2

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2020-06-29
Completion: 2024-12-26
Conditions
Tay-Sachs Disease Sandhoff Disease
Interventions
DRUG
No Results Yet
NCT04174391 | ACTIVE_NOT_RECRUITING | NA
766 Participants

Lifestyles and Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2020-05-29
Completion: 2026-12-31
Conditions
Malignant Tumor of Breast
Interventions
BEHAVIORAL
No Results Yet
NCT04153682 | COMPLETED | NA
116 Participants

Trial on a Strategy Combining Rapid Diagnostic Testing and Antimicrobial Stewardship to Improve Antibiotic Use in Patients with Hospital-acquired Pneumonia.

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2020-02-21
Completion: 2023-08-31
Conditions
Hospital-acquired Pneumonia
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04142606 | RECRUITING
1500 Participants

LUMIERE on the FETUS

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2019-12-06
Completion: 2026-12-31
Conditions
Pregnancy
Interventions
OTHER
No Results Yet
NCT04080622 | COMPLETED | PHASE3
100 Participants

Evaluate the Efficacy of Selenium for the Prevention of Chemotherapy-induced Mucositis During Autologous Stem Cell Transplantation.

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2019-10-10
Completion: 2023-10-08
Conditions
Mucositis Oral Stem Cell Transplant Complications
Interventions
DRUG
No Results Yet
NCT04072406 | TERMINATED | NA
21 Participants

A Self-Directed Mindfulness Meditation Intervention in Gynecologic Cancer Patients

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2019-07-23
Completion: 2020-04-10
Conditions
Stage III Gynecologic Cancer Stage IV Gynecologic Cancer
Interventions
OTHER
No Results Yet
NCT04060355 | COMPLETED | NA
120 Participants

Savvy System Project

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2021-08-04
Completion: 2023-10-31
Conditions
Caregiver Burnout Dementia
Interventions
BEHAVIORAL
Results Available
NCT03869476 | COMPLETED | NA
133 Participants

Pilot Study for the Development of a Diagnostic Score to Differentiate Myeloproliferative Neoplasms.

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2019-07-30
Completion: 2024-01-30
Conditions
Myeloproliferative Disorder Essential Thrombocythemia Primary Myelofibrosis, Prefibrotic Stage Primary Myelofibrosis, Fibrotic Stage
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03837977 | COMPLETED | PHASE2
58 Participants

Second-line Therapy for Patients With Progressive Poorly Differentiated Extra-pulmonary Neuroendocrine Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2018-11-13
Completion: 2024-11-26
Conditions
Oncology Neuroendocrine Carcinoma
Interventions
DRUG
No Results Yet
NCT03812913 | RECRUITING
70 Participants

Neuropsychological Assessment of Children and Adolescents With Turner Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2019-09-05
Completion: 2025-12-05
Conditions
Turner Syndrome Isolated Growth Hormone Deficiency Cognitive Functions Social Cognition Pediatrics
Interventions
BEHAVIORAL
No Results Yet
NCT03787264 | COMPLETED | PHASE2
46 Participants

Sequential Regimen of Bendamustin-Debulking Followed by Obinutuzumab, Acalabrutinib and Venetoclax in Patients with Relapsed/refractory CLL

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2019-01-14
Completion: 2021-02-11
Conditions
Chronic Lymphoid Leukemia
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT03756051 | COMPLETED
2871 Participants

Harms of Hepatocellular Carcinoma Surveillance

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2018-04-01
Completion: 2022-06-30
Conditions
Carcinoma, Hepatocellular
Interventions
OTHER
No Results Yet
NCT03715738 | COMPLETED | NA
30 Participants

MEasurement by a Numerical Approach of BREAst Volume

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2019-07-02
Completion: 2023-04-18
Conditions
Breast Asymmetry, 3D
Interventions
OTHER
No Results Yet
NCT03687086 | COMPLETED | NA
188 Participants

Sleep Without Insomnia or The Use of Chronic Hypnotics

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2018-12-11
Completion: 2023-11-27
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
OTHER
Results Available
NCT03609801 | COMPLETED | NA
799 Participants

The Duluth Model and ACTV for Domestic Violence

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2018-06-29
Completion: 2022-05-31
Conditions
Domestic Violence
Interventions
BEHAVIORAL
No Results Yet
NCT03272373 | COMPLETED | NA
160 Participants

NexGen TM Tibia Clinical Outcomes Study

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2017-10-03
Completion: 2023-03-30
Conditions
Osteoarthritis Rheumatoid Arthritis Traumatic Arthritis Polyarthritis Collagen Disorders and/or Avascular Necrosis of the Femoral Condyle Post-traumatic Loss of Joint Configuration Moderate Valgus, Varus, or Flexion Deformities
Interventions
DEVICE
Results Available
NCT03231085 | COMPLETED | NA
100 Participants

Comparison of the Rate of Preoperative Haemoglobin After Administration of Epoetin Alpha Associated With an Oral Medical Supplementation Versus Intravenous Before Surgery of Craniosynostosis at the Child

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2017-10-31
Completion: 2024-04-11
Conditions
Craniosynostosis
Interventions
DRUG
No Results Yet
NCT03003533 | COMPLETED | PHASE1/PHASE2
25 Participants

A Gene Transfer Study for Hemophilia A

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2017-01-26
Completion: 2023-12-05
Conditions
Hemophilia A
Interventions
GENETIC
Results Available
NCT02951091 | COMPLETED | NA
400 Participants

Biomarker-Integrated Umbrella, Advanced Gastric Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2016-01-01
Completion: 2021-12-31
Conditions
Gastric Cancer
Interventions
OTHER
No Results Yet
NCT02950051 | COMPLETED | PHASE3
926 Participants

Standard Chemoimmunotherapy (FCR/BR) Versus Rituximab + Venetoclax (RVe) Versus Obinutuzumab (GA101) + Venetoclax (GVe) Versus Obinutuzumab + Ibrutinib + Venetoclax (GIVe) in Fit Patients with Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without Del(17p) or TP53 Mutation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2016-12-13
Completion: 2024-02-29
Conditions
Chronic Lymphocytic Leukemia
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT02915198 | RECRUITING | PHASE4
7410 Participants

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2023-04-03
Completion: 2029-03-31
Conditions
Prediabetic State Atherosclerosis Metformin
Interventions
DRUG
No Results Yet
NCT02863718 | COMPLETED | PHASE3
515 Participants

Ibrutinib in Previously Untreated Binet Stage a Chronic Lymphocytic Leukemia with Risk of Disease Progression

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2014-04-30
Completion: 2019-03-07
Conditions
Chronic Lymphocytic Leukemia
Interventions
DRUG
No Results Yet
NCT02863692 | RECRUITING
8000 Participants

Registry of the German CLL Study Group

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2013-08-31
Completion: 2026-12-31
Conditions
CLL SLL HCL Richterยดs Transformation Leukemia, Prolymphocytic, B-Cell Leukemia, Prolymphocytic, T-Cell T-LGL Leukemia NK-LGL Leukemia
No Results Yet
NCT02606162 | COMPLETED
912 Participants

Outcomes of Severe Osteoporotic Fractures Hospitalized in France: the CROSS Cohort

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2016-06-08
Completion: 2018-06-08
Conditions
Severe Fragility Fracture
No Results Yet
NCT02000895 | RECRUITING
300 Participants

Early Detection of Progressive Kidney Disease in Preterm Infants

Study Type: OBSERVATIONAL
Last Updated: 2024-12-30
Start Date: 2011-07-23
Completion: 2028-01-01
Conditions
Chronic Kidney Diseases Cardiovascular Diseases
No Results Yet
NCT01266096 | ACTIVE_NOT_RECRUITING | NA
10 Participants

PET Imaging of Patients With Melanoma and Malignant Brain Tumors Using an 124I-labeled cRGDY Silica Nanomolecular Particle Tracer: A Microdosing Study

Study Type: INTERVENTIONAL
Last Updated: 2024-12-30
Start Date: 2011-01-31
Completion: 2025-12-31
Conditions
Newly Diagnosed or Recurrent Metastatic Melanoma Patients Malignant Brain Tumors
Interventions
DRUG
No Results Yet
NCT06751420 | COMPLETED
383 Participants

Circle of Willis Variants in Nepali Population Evaluated in TOF MR Angiography

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2024-07-01
Completion: 2024-12-20
Conditions
Circle of Willis; Aneurysm, Congenital, Ruptured
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06751394 | NOT_YET_RECRUITING | PHASE2
44 Participants

Preoperative Chemoradiotherapy and Toripalimab in Locally Recurrent Rectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2025-01-01
Completion: 2028-12-31
Conditions
Recurrent Rectal Cancer
Interventions
DRUG RADIATION PROCEDURE
No Results Yet
NCT06751368 | COMPLETED
232 Participants

The Fate of Aortic Valve After SAS Surgery in Children

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2008-01-01
Completion: 2024-11-30
Conditions
Subaortic Stenosis Congenital Heart Disease Aortic Regurgitation
No Results Yet
NCT06751342 | ACTIVE_NOT_RECRUITING
96 Participants

Using Psychophysics Methods to Investigate Sensory Dominance After Cataract Surgery

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2024-12-01
Completion: 2025-12-30
Conditions
Cataract
No Results Yet
NCT06751316 | NOT_YET_RECRUITING | NA
42 Participants

Clinical and Radiographic Evaluation of MTA Pulpotomy Versus Conventional Pulpectomy in Primary Molars With Irreversible Pulpitis

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2025-01-01
Completion: 2025-12-01
Conditions
Decayed Primary Molars With Irreversible Pulpitis
Interventions
PROCEDURE
No Results Yet
NCT06751303 | RECRUITING | NA
100 Participants

Patient Preferences for Precision Medicine: Determining Optimal Patient Quality of Life Using PARPi's

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2023-09-17
Completion: 2026-09-16
Conditions
Ovarian Cancer Quality of Life
Interventions
OTHER
No Results Yet
NCT06751277 | NOT_YET_RECRUITING | PHASE2
26 Participants

QL1706 Combined with Chemotherapy in the Treatment of Recurrent or Metastatic Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2025-02-01
Completion: 2026-12-30
Conditions
Recurrent or Metastatic Endometrial Cancer
Interventions
DRUG
No Results Yet
NCT06751264 | NOT_YET_RECRUITING | NA
137 Participants

Evaluation of the Efficacy and Safety of Microwave Ablation of Uterine Adenomyosis Under Improved Ultrasound Guidance

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2025-01-01
Completion: 2027-12-31
Conditions
Adenomyosis of Uterus
Interventions
PROCEDURE
No Results Yet
NCT06751212 | NOT_YET_RECRUITING
62 Participants

Observation on the Efficacy of Radiofrequency Ablation for Patients With Moderate to Severe Gastric Atrophy With Enterosis With or Without Atrophy of Intraepithelial Neoplasia: An Observational Study

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2024-12-31
Completion: 2027-12-31
Conditions
Atrophic Gastritis
Interventions
PROCEDURE
No Results Yet
NCT06751199 | RECRUITING | NA
16 Participants

UCMSCs Combined With Allogeneic Islet Transplantation for the Treatment of Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2024-12-30
Completion: 2026-07-30
Conditions
Diabetes
Interventions
DRUG
No Results Yet
NCT06751160 | RECRUITING | NA
30 Participants

Comparative Effects of Dry Needling Versus Soft Tissue Mobilization on Hamstring Tightness

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2024-07-15
Completion: 2024-12-30
Conditions
Hamstring Tightness Chronic Low-back Pain
Interventions
OTHER
No Results Yet
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