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Clinical Trials

Showing trials with last updates posted in 2020.

NCT01309698 | COMPLETED | PHASE4
24 Participants

Drug Interaction of Vildagliptin (LAF237) With Voglibose in Japanese Patients With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2011-02-28
Completion: 2011-04-30
Conditions
Type 2 Diabetes
Interventions
DRUG
No Results Yet
NCT01266135 | TERMINATED | PHASE2
40 Participants

Safety and Efficacy of QAX576 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-12-31
Completion: 2013-04-30
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
DRUG
No Results Yet
NCT01253603 | COMPLETED | PHASE2
170 Participants

Efficacy, Safety, and Pharmacokinetics of QAW039

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-11-30
Completion: 2011-09-30
Conditions
Persistent Asthma
Interventions
DRUG
No Results Yet
NCT01242774 | COMPLETED | PHASE1
46 Participants

Safety & Efficacy Study of Oral Panobinostat (LBH589) With Chemotherapy in Patients < 65 Years Old With Acute Myeloid Leukemia (AML)

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-10-31
Completion: 2014-05-31
Conditions
Acute Myeloid Leukemia (AML)
Interventions
DRUG
No Results Yet
NCT01240655 | COMPLETED | PHASE1
76 Participants

A Study of LCL161 in Combination With Weekly Paclitaxel in Adult Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2011-04-30
Completion: 2015-01-31
Conditions
Solid Tumors
Interventions
DRUG
No Results Yet
NCT01232595 | COMPLETED | PHASE2
109 Participants

Safety and Efficacy of Multiple Daily Dosing of Oral LFF571 in Patients With Moderate Clostridium Difficile Infections

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-10-31
Completion: 2013-07-31
Conditions
Moderate Clostridium Difficile Infection
Interventions
DRUG
No Results Yet
NCT01208831 | COMPLETED | PHASE1
45 Participants

An East Asian Study of LDE225

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-10-31
Completion: 2013-10-31
Conditions
Advanced Solid Tumor Cancers Medulloblastoma Basal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT01130064 | COMPLETED | PHASE2
259 Participants

Efficacy of QAX576 in Asthma

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-05-31
Completion: 2012-04-30
Conditions
Asthma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT01103037 | TERMINATED | PHASE2
8 Participants

Efficacy, Safety and Pharmacokinetics of QAV680 Versus Placebo in Patients With Asthma

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-03-31
Completion: 2010-09-30
Conditions
Asthma
Interventions
DRUG
No Results Yet
NCT01069692 | COMPLETED | PHASE3
115 Participants

Placebo Versus SBR759 in Lowering Phosphate in Dialysis Patients

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-02-28
Completion: 2010-10-31
Conditions
Hyperphosphatemia Chronic Kidney Disease
Interventions
DRUG
No Results Yet
NCT01068613 | COMPLETED | PHASE2
62 Participants

Safety and Efficacy of Multiple Doses of QAX028 in Chronic Obstructive Pulmonary Disease (COPD) Patients

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-01-31
Completion: 2010-08-31
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DRUG
No Results Yet
NCT01058434 | COMPLETED | PHASE2
43 Participants

Safety and Efficacy of TKI258 in Relapsed or Refractory Multiple Myeloma Patients, Who Are With or Without t(4;14) Chromosomal Translocation

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-05-31
Completion: 2013-02-28
Conditions
Relapsed or Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT01055483 | COMPLETED | PHASE1
59 Participants

A Phase Ib, Open-label, Multi-center Dose-finding Study of Oral Panobinostat (LBH589) in Combination With Ara-C and Mitoxantrone as Salvage Therapy for Refractory or Relapsed Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-09-30
Completion: 2012-02-29
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT01027377 | COMPLETED | PHASE1
16 Participants

Study of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Subjects With Severe Hemophilia A

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-12-31
Completion: 2010-07-31
Conditions
Severe Hemophilia A
Interventions
DRUG
No Results Yet
NCT01027364 | COMPLETED | PHASE3
123 Participants

Study of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Participants With Hemophilia B

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-12-31
Completion: 2012-07-31
Conditions
Severe Hemophilia B
Interventions
DRUG
Results Available
NCT01007968 | COMPLETED | PHASE1
25 Participants

Pharmacokinetics and Safety of Panobinostat in Patients With Advanced Solid Tumors and Various Degrees of Hepatic Function

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-03-31
Completion: 2012-11-30
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT00997399 | COMPLETED | PHASE1
37 Participants

Study to Evaluate Panobinostat (DACi) Pharmacokinetics and Safety in Solid Tumors and Varying Renal Function

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-03-31
Completion: 2014-06-30
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT00987545 | TERMINATED | PHASE2
3 Participants

Efficacy 2 Part Study of Identification of Keloid Biomarkers and Effect of QAX576 on Keloid Recurrence

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-06-30
Completion: 2010-11-30
Conditions
Keloids
Interventions
DRUG
No Results Yet
NCT00986882 | COMPLETED | PHASE2
183 Participants

To Evaluate the Safety, Tolerability and Analgesic Efficacy of SAF312 in Postoperative Dental Pain Patients

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-09-30
Completion: 2011-03-31
Conditions
Postoperative Pain
Interventions
DRUG
No Results Yet
NCT00983060 | COMPLETED | PHASE2
59 Participants

Adaptive-design Dose Finding Study to Assess the Antiviral Efficacy and Safety of NIM811 Administered in Combination With Standard of Care (SOC) in Relapsed Hepatitis C Virus 1 (HCV-1) Infected Patients

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-09-30
Completion: 2011-04-30
Conditions
Chronic Hepatitis C Genotype-1 Relapse
Interventions
DRUG
No Results Yet
NCT00958971 | COMPLETED | PHASE2
43 Participants

Safety and Efficacy of TKI258 in FGFR1 Amplified and Non-amplified Metastatic HER2 Negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-07-31
Completion: 2011-03-31
Conditions
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT00929968 | COMPLETED | PHASE2
35 Participants

Safety, Tolerability and Pharmacokinetics of Multiple Doses of VAK694 in Atopic Subjects With Seasonal Rhinitis

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-06-30
Completion: 2011-02-28
Conditions
Allergic Rhinitis
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT00913653 | COMPLETED | PHASE2
30 Participants

Safety/Tolerability, Pharmacokinetics/Pharmacodynamics (PK/PD) of LCZ696 in Patients With Stable Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-05-31
Completion: 2009-07-31
Conditions
Heart Failure
Interventions
DRUG
No Results Yet
NCT00907894 | COMPLETED | PHASE1
22 Participants

Pharmacokinetics and Safety of Single-Dose Telbivudine in Children and Adolescents With Chronic Hepatitis B

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-02-28
Completion: 2012-03-31
Conditions
Chronic Hepatitis B
Interventions
DRUG
No Results Yet
NCT00880308 | COMPLETED | PHASE1
103 Participants

Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-03-31
Completion: 2013-07-31
Conditions
Advanced Solid Tumor Cancers Medulloblastoma Basal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT00846989 | COMPLETED | PHASE1/PHASE2
276 Participants

Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2009-01-31
Completion: 2009-04-30
Conditions
Glaucoma Ocular Hypertension
Interventions
DRUG
No Results Yet
NCT00790426 | COMPLETED | PHASE2
44 Participants

Phase II Study of TKI258 in Advanced Urothelial Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2010-03-31
Completion: 2012-04-30
Conditions
Urothelial Cancer
Interventions
DRUG
No Results Yet
NCT00788931 | COMPLETED | PHASE1
15 Participants

A Trial l of Panobinostat Given in Combination With Trastuzumab and Paclitaxel in Adult Female Patients With HER2 Positive Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2008-12-31
Completion: 2010-08-31
Conditions
HER-2 Positive Breast Cancer Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT00757757 | TERMINATED | PHASE1/PHASE2
3 Participants

A Phase I/II Open-label Study of MCS110 in Patients With Prostate Cancer and Bone Metastases

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2008-09-30
Completion: 2009-08-31
Conditions
Prostate Cancer Bone Metastases
Interventions
DRUG
No Results Yet
NCT00750295 | COMPLETED | PHASE1/PHASE2
60 Participants

A Clinical Study to Evaluate the Safety, Tolerability and Activity of a New Phosphate Binder (SBR759) in Patients With Chronic Kidney Disease on Hemodialysis

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2007-02-28
Completion: 2008-01-31
Conditions
Chronic Kidney Disease
Interventions
DRUG
No Results Yet
NCT00739414 | COMPLETED | PHASE1
14 Participants

Dose-escalating Study of LBH589 in Adult Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2008-07-31
Completion: 2009-11-30
Conditions
Cancer Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT00728351 | COMPLETED | PHASE3
317 Participants

Efficacy and Safety of Fixed Combination Therapy of Vildagliptin and Metformin (25/1000 mg Bid) in Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy (HbA1c 7.0-9.5%)

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2008-06-30
Completion: 2010-02-28
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT00716716 | COMPLETED | PHASE1
10 Participants

Phase I/IIa Study of FIXFc in Hemophilia B Patients

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2008-04-30
Completion: 2009-10-31
Conditions
Hemophilia B
Interventions
DRUG
No Results Yet
NCT00704483 | COMPLETED | PHASE2
321 Participants

Efficacy of SBR759 in Lowering Serum Phosphate Levels in Chronic Kidney Disease Patients on Hemodialysis

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2008-07-31
Completion: 2010-08-31
Conditions
Hyperphosphatemia Patients With Chronic Kidney Disease on 3x/Week Replacement Therapy
Interventions
DRUG
No Results Yet
NCT00663832 | COMPLETED | PHASE1
44 Participants

A Dose Finding Study With I.V. Panobinostat (LBH589), Docetaxel, and Prednisone in Patients With Hormone Refractory Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2008-02-29
Completion: 2011-12-31
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT00624702 | COMPLETED | PHASE1
98 Participants

Tolerability of Indacaterol Salts (Maleate, Xinafoate and Acetate) in Comparison to Placebo in Patients With Mild to Moderate Persistent Asthma

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2008-02-29
Completion: 2008-09-30
Conditions
Asthma
Interventions
DRUG
No Results Yet
NCT00581997 | TERMINATED | PHASE2
8 Participants

QAX576 in Patients With Pulmonary Fibrosis Secondary to Systemic Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2007-12-31
Completion: 2009-04-30
Conditions
Pulmonary Fibrosis Secondary to Systemic Sclerosis
Interventions
DRUG
No Results Yet
NCT00570284 | COMPLETED | PHASE1
36 Participants

A Study to Investigate the Effect of Food on Oral LBH589 Absorption in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2007-11-30
Completion: 2011-02-28
Conditions
Cancer
Interventions
DRUG
No Results Yet
NCT00535951 | COMPLETED | PHASE1
18 Participants

Pharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural Mesothelioma

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2007-11-30
Completion: 2009-01-31
Conditions
Carcinoma, Non-Small-Cell Lung Mesothelioma
Interventions
DRUG
No Results Yet
NCT00532675 | COMPLETED | PHASE1
46 Participants

Safety Study of LBH589 When Given in Combination With Lenalidomide and Dexamethasone in Adult Patients With Multiple Myeloma.

Study Type: INTERVENTIONAL
Last Updated: 2020-12-19
Start Date: 2008-04-22
Completion: 2017-11-08
Conditions
Multiple Myeloma
Interventions
DRUG COMBINATION_PRODUCT
No Results Yet
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