Criteria for Selecting First-line Metastatic Treatment for Patients With Urothelial Carcinoma

NCT ID: NCT07339878

Last Updated: 2026-01-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-04-20

Study Completion Date

2026-04-20

Brief Summary

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The standard first-line treatment for metastatic urothelial carcinoma has become the combination of Enfortumab Vedotin and Pembrolizumab following the publication of the EV-302 study results at the end of 2024. Another standard remains in 2025 for patients who are not eligible for the EV Pembrolizumab combination, namely platinum-based chemotherapy +/- avelumab in cases of non-progression. The objective of the FLORAL study is to determine the characteristics of these patients and the reasons that led clinicians to prefer a first-line treatment based on platinum salts.

Detailed Description

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Conditions

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Metastatic Urothelial Carcinoma

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients over 18 years of age
* Metastatic urothelial carcinoma
* Treated with first-line metastatic therapy since October 2024

Exclusion Criteria

* Patient who expressed opposition to participating in the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Strasbourg, France

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Service Oncologie Médicale - CHU de Strasbourg - France

Strasbourg, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Philippe Barthélémy, MD

Role: CONTACT

33 3 88 12 76 70

Facility Contacts

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Philippe Barthélémy, MD

Role: primary

33 3 88 12 76 70

Other Identifiers

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9770

Identifier Type: -

Identifier Source: org_study_id

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