A Clinical Trial to Compare Forms of MK-1167 in Healthy People (MK-1167-011)

NCT ID: NCT07334860

Last Updated: 2026-01-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

PHASE1

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-02-02

Study Completion Date

2026-05-26

Brief Summary

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Researchers are looking for new ways to treat Alzheimer's disease (AD). AD is a brain disease that causes a gradual decline in memory, thinking, and ability to carry out daily tasks. MK-1167 is a study medicine designed to treat symptoms of AD. Before giving a study medicine to people with a health condition, researchers first do studies in healthy people to find a safe dose of the study medicine.

The goals of the trial are to learn:

* What happens to different forms of MK-1167 in a healthy person's body over time
* About the safety of MK-1167 and if people tolerate it

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SEQUENTIAL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Arm 1: MK-1167 Form 2

Participants receive MK-1167 Form 2 orally.

Group Type EXPERIMENTAL

MK-1167

Intervention Type DRUG

Oral administration

Arm 2: MK-1167 Form 1

Participants receive MK-1167 Form 1 orally.

Group Type EXPERIMENTAL

MK-1167

Intervention Type DRUG

Oral administration

Interventions

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MK-1167

Oral administration

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Is in good health
* Has a body mass index (BMI) ≥18 and ≤ 32 kg/m\^2, inclusive

Exclusion Criteria

* Has a history of clinically significant endocrine, gastrointestinal, cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological abnormalities or diseases
* Is a smoker and/or has used nicotine or nicotine-containing products within the past 3 months.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Merck Sharp & Dohme LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Medical Director

Role: STUDY_DIRECTOR

Merck Sharp & Dohme LLC

Related Links

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http://www.merckclinicaltrials.com

Merck Clinical Trials Information

Other Identifiers

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MK-1167-011

Identifier Type: OTHER

Identifier Source: secondary_id

1167-011

Identifier Type: -

Identifier Source: org_study_id

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