Diagnostic Performance of PIC Cystogram vs VCUG in Children
NCT ID: NCT07334821
Last Updated: 2026-01-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
NOT_YET_RECRUITING
NA
60 participants
INTERVENTIONAL
2026-02-01
2026-04-01
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
The main questions it aims to answer are:
Does PIC cystography detect VUR at a rate comparable to VCUG?
How well do PIC cystography and VCUG correlate in identifying low-grade versus high-grade VUR?
Researchers will compare PIC cystography findings with prior VCUG results to determine agreement between the two diagnostic methods and their ability to detect clinically relevant reflux.
Participants will:
Undergo PIC cystography performed during endoscopic surgery
Have contrast instilled near each ureteral orifice under fluoroscopic monitoring
Be evaluated for the presence and grade of vesicoureteral reflux
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Diagnosing Vesicoureteric Reflux in Children by Direct Isotope Cystography and Contrast Enhanced Voiding Ultrasonography
NCT06138080
Prospective Pediatric Vesicoureteral Reflux Surgery Database
NCT01373385
Clinical Applications of Contrast-Enhanced Ultrasonography in Pediatric Population - Intravesicle Administration
NCT02986477
Evaluation of the Efficiency of Autologous Adipocytes Graft in Endoscopic Treatment in Vesico-Renal Reflux in Children
NCT00367159
Ureteropelvic Junction Obstruction in Early Childhood: Comparison of Surgical Therapy and Surveillance. A Prospective, Randomized, Controlled Multi-Center Study
NCT00444431
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
NON_RANDOMIZED
SINGLE_GROUP
DIAGNOSTIC
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
PIC cystography
PIC cystography
PIC cystography is performed intraoperatively during endoscopic surgery. A pediatric cystoscope is positioned adjacent to each ureteral orifice, and contrast medium is instilled by gravity from a height of 1 meter under fluoroscopic guidance. The presence and grade of vesicoureteral reflux are recorded for each renal unit. The procedure is carried out in a standardized manner by an investigator blinded to prior VCUG findings
VCUG
VCUG performed
VCUG Group
VCUG
VCUG performed
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
PIC cystography
PIC cystography is performed intraoperatively during endoscopic surgery. A pediatric cystoscope is positioned adjacent to each ureteral orifice, and contrast medium is instilled by gravity from a height of 1 meter under fluoroscopic guidance. The presence and grade of vesicoureteral reflux are recorded for each renal unit. The procedure is carried out in a standardized manner by an investigator blinded to prior VCUG findings
VCUG
VCUG performed
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Undergoing endoscopic urological surgery
* With or without a prior VCUG performed for urinary tract infection or other clinical indications
* Availability of VCUG results for participants who previously underwent VCUG
* Written informed consent obtained from parents or legal guardians
Exclusion Criteria
* Known neurogenic bladder or severe lower urinary tract dysfunction
* Active urinary tract infection at the time of endoscopic procedure
* Inability to undergo fluoroscopic imaging (e.g., contrast allergy)
* Incomplete clinical or imaging data
18 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Tarik Emre Sener
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Tarik Emre Sener
Associated Professor
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Marmara University School of Medicine Urology Department
Istanbul, Pendik, Turkey (Türkiye)
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
MAR.UAD.0028
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.