GYKO-Based L-Test Reliability in Parkinson's Disease

NCT ID: NCT07327346

Last Updated: 2026-01-21

Basic Information

• Recruitment Status: ACTIVE_NOT_RECRUITING
• Total Enrollment: 25 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-12-01
• Study Completion Date: 2026-05-01

Brief Summary

This study aims to investigate the interrater and test-retest reliability of GYKO-based postural sway measurements collected during the L-Test and Timed Up and Go (TUG) test in individuals with Parkinson's disease (Hoehn & Yahr stages 1-3). Two independent raters will perform GYKO-based assessments of the L-Test and TUG with a 20-minute interval. Participants will return one week later to repeat the same procedures for test-retest reliability. Concurrent validity will be examined using the Berg Balance Scale.

Detailed Description

This study aims to investigate the test-retest and interrater reliability, as well as the concurrent validity, of GYKO-based postural sway measurements obtained during the L-Test and the Timed Up and Go (TUG) test in individuals with Parkinson's disease. Participants diagnosed with idiopathic Parkinson's disease (Hoehn & Yahr stages 1-3) will be evaluated using the GYKO inertial measurement unit, which provides quantitative postural sway parameters including ellipse area, mean length, mediolateral and anteroposterior mean length, mediolateral and anteroposterior mean distance, and velocity.

Two independent raters will perform GYKO-based assessments of the L-Test and TUG on the same day, with a 20-minute interval between raters, to determine interrater reliability. Participants will return one week later to repeat the same procedures, allowing assessment of test-retest reliability.

To examine concurrent validity, participants' functional balance will also be assessed using the Berg Balance Scale, and correlations between GYKO variables and clinical mobility tests (L-Test and TUG) will be analyzed.

Conditions

Parkinson Disease

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: PROSPECTIVE

Study Groups

Parkinson's disease group

Parkinson's disease patients with stage 1-3 hoehn yahr

GYKO-Based Postural Sway Assessment

Intervention Type: OTHER

This procedure involves obtaining postural sway parameters using the GYKO inertial measurement device during the Time Up and Go (TUG) test and L-Test. No therapeutic intervention is applied.

Time Up and Go Test: Timed Up and Go (TUG) is a standardized functional mobility test used to assess dynamic balance and gait performance. Participants are instructed to stand up from a standard-height chair, walk 3 meters, turn around, walk back to the chair, and sit down. The total time to complete the task (in seconds) is recorded. Higher times indicate reduced mobility.

L Test: Time (in seconds) to complete the L-Test of Functional Mobility. The test requires participants to stand up from a chair, walk 3 m, execute a 90° turn, walk another 7 m, perform a 180° turn, and return along the same path (total walking distance ≈ 20 m). The task ends when the participant sits back down. The total time to complete the task (in seconds) is recorded. Higher times indicate reduced mobility.

Interventions

GYKO-Based Postural Sway Assessment

This procedure involves obtaining postural sway parameters using the GYKO inertial measurement device during the Time Up and Go (TUG) test and L-Test. No therapeutic intervention is applied.

Time Up and Go Test: Timed Up and Go (TUG) is a standardized functional mobility test used to assess dynamic balance and gait performance. Participants are instructed to stand up from a standard-height chair, walk 3 meters, turn around, walk back to the chair, and sit down. The total time to complete the task (in seconds) is recorded. Higher times indicate reduced mobility.

L Test: Time (in seconds) to complete the L-Test of Functional Mobility. The test requires participants to stand up from a chair, walk 3 m, execute a 90° turn, walk another 7 m, perform a 180° turn, and return along the same path (total walking distance ≈ 20 m). The task ends when the participant sits back down. The total time to complete the task (in seconds) is recorded. Higher times indicate reduced mobility.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Diagnosis of idiopathic Parkinson's disease
• Hoehn & Yahr stage 1-3
• Ability to walk independently with or without an assistive device
• Ability to follow verbal instructions
• Age 50-85

Exclusion Criteria

• Other neurological, vestibular, or musculoskeletal disorders affecting balance
• Deep brain stimulation (DBS) implant
• Severe visual or auditory impairment

• Minimum Eligible Age: 50 Years
• Maximum Eligible Age: 85 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Hasan Kalyoncu University

OTHER

Sponsor Role: lead

Responsible Party

Büşra Akıncı

MSc

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Büşra Akıncı, MSc

Role: STUDY_CHAIR

Hasan Kalyonuc University

Günseli Usgu, Assoc. Prof.

Role: STUDY_DIRECTOR

Hasan Kalyoncu University

Saadet Nur Çörekçioğlu, P.T.

Role: PRINCIPAL_INVESTIGATOR

Hasan Kalyoncu University

Locations

Hasan Kalyoncu University

Gaziantep, Şahinbey, Turkey (Türkiye)

Countries

Turkey (Türkiye)

References

Haas B, Clarke E, Elver L, Gowman E, Mortimer E, Byrd E. The reliability and validity of the L-test in people with Parkinson's disease. Physiotherapy. 2019 Mar;105(1):84-89. doi: 10.1016/j.physio.2017.11.218. Epub 2017 Dec 5.

Reference Type: BACKGROUND

PMID: 29395266 (View on PubMed)

Zampieri C, Salarian A, Carlson-Kuhta P, Aminian K, Nutt JG, Horak FB. The instrumented timed up and go test: potential outcome measure for disease modifying therapies in Parkinson's disease. J Neurol Neurosurg Psychiatry. 2010 Feb;81(2):171-6. doi: 10.1136/jnnp.2009.173740. Epub 2009 Sep 2.

Reference Type: BACKGROUND

PMID: 19726406 (View on PubMed)

Other Identifiers

HKU/PH/2

Identifier Type: -

Identifier Source: org_study_id