Omnipod-5 A French Prospective Multicentric Study in Real World (Optimal-B)

NCT ID: NCT07317102

Last Updated: 2026-01-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

152 participants

Study Classification

OBSERVATIONAL

Study Start Date

2026-02-28

Study Completion Date

2027-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this postmarket clinical investigation is to evaluate the levels of glycemic control, quality of life, and satisfaction, as well as the patient experience, and acute diabetes complication rates provided by the Omnipod 5 Automated Insulin Delivery System (referred to as the Omnipod 5 System) in a real-world setting.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Twelve-month, real-world, non-interventional, prospective follow-up of adult and pediatric patients aged more than 2 years old, prescribed the commercially available FreeStyle Libre 2 Plus configuration of the Omnipod 5 Automated Insulin Delivery System in France.

OPTIMAL-B study (Omnipod 5 - A French Prospective Multicentric Study in Real World), aims to provide the requisite real-world data on the glycemic control, quality of life, safety, and device usage profiles of users of the Omnipod 5 System during the 12 months after starting using Omnipod 5 in automated mode.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Diabetes Type 1 Diabetes Diabetes Mellitus

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Omnipod 5 User

Participation of each patient begins at inclusion and continues until the end-of-study visit, 12 months (± 1 month) following first initiation of automated mode of the Omnipod 5 System

Omnipod 5

Intervention Type DEVICE

The Omnipod 5 Automated Insulin Delivery System (Omnipod 5 System) is a tubeless insulin pump with a mono-hormonal insulin delivery system designed to deliver U-100 insulin subcutaneously for the management of type 1 diabetes in people aged 2 years and older who require insulin.

The Omnipod 5 System is intended to function as an automated insulin delivery system when used with compatible Continuous Glucose Monitoring (CGM) systems.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Omnipod 5

The Omnipod 5 Automated Insulin Delivery System (Omnipod 5 System) is a tubeless insulin pump with a mono-hormonal insulin delivery system designed to deliver U-100 insulin subcutaneously for the management of type 1 diabetes in people aged 2 years and older who require insulin.

The Omnipod 5 System is intended to function as an automated insulin delivery system when used with compatible Continuous Glucose Monitoring (CGM) systems.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patient with T1D aged ≥ 2 years.
* Patient prescribed, less than a year ago, a commercially available confi guration of the Omnipod 5 System using a FreeStyle Libre 2 Plus sensor.
* Patient has never used the Omnipod 5 System prior to inclusion.
* Patient has not objected to the use of their personal data for this study.
* Patient or legal guardian has an email address and mobile phone number.
* Patient (and legal guardians if the patient is a minor) is able to understand study information and Non-Opposition form.
* Patient (and legal guardians if the patient is a minor) is able to understand and complete questionnaires in French.
* Patient is covered by the local social security system

Exclusion Criteria

* Patient is currently pregnant.
* Patient presents an allergy to the materials of the Omnipod 5 System (patch, cannula, CGM).
* Patient is unable to be followed by the same investigation site for the duration of the study or is unwilling or unable to maintain contact with the healthcare professional.
* Patient is already participating in a clinical trial or in another study precluding their participation in other studies.
* Adult under guardianship, curatorship or tutorship.
* Adult otherwise deprived of liberty.
Minimum Eligible Age

2 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Insulet Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Jean-Pierre Riveline, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Centre Universitaire du Diabète et ses complications Hôpital Lariboisière

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

CHU Angers

Angers, , France

Site Status

CHU Besançon - Hôpital de Jean Minjoz

Besançon, , France

Site Status

APHP Hopital Avicenne

Bobigny, , France

Site Status

CHU Bordeaux - Hôpital Pellegrin

Bordeaux, , France

Site Status

CHU Bordeaux - Hôpital St-André

Bordeaux, , France

Site Status

CHU Brest - Hôpital de la Cavale Blanche

Brest, , France

Site Status

Hôpital Femme Mère Enfant

Bron, , France

Site Status

Centre Hospitalier Sud Francilien

Corbeil-Essonnes, , France

Site Status

CIRDIA

Dijon, , France

Site Status

CHU Dijon - Hôpital François Mitterrand

Dijon, , France

Site Status

GH La Rochelle-Ré-Aunis - Hôpital Saint Louis

La Rochelle, , France

Site Status

APHP Hôpital Bicêtre

Le Kremlin-Bicêtre, , France

Site Status

Institut de Diabétologie et de Nutrition du Centre

Mainvilliers, , France

Site Status

Fondation Ambroise Paré - Hôpital Européen de Marseille

Marseille, , France

Site Status

CHU Montpellier - Hôpital Lapeyronie

Montpellier, , France

Site Status

Institut Saint Pierre

Palavas-les-Flots, , France

Site Status

APHP Hôpital Lariboisière

Paris, , France

Site Status

APHP Hopital Robert Debré

Paris, , France

Site Status

CH Périgueux

Périgueux, , France

Site Status

Clinique Saint Jean de Védas

Saint-Jean-de-Védas, , France

Site Status

CHRU Strasbourg

Strasbourg, , France

Site Status

CHU Tours

Tours, , France

Site Status

Countries

Review the countries where the study has at least one active or historical site.

France

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Trang Ly, MBBS, PhD

Role: CONTACT

978-600-7000

Bonnie Dumais

Role: CONTACT

978-600-7000

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Lucie DUFOUR

Role: primary

Julie GUCCIARDI

Role: primary

Sarah YAHIAOUI

Role: primary

Caroline BOUYSSOU

Role: primary

Bogdan CATARGI

Role: primary

Pascale Quiniou

Role: primary

Karima RENDJA

Role: primary

Catherine PETIT

Role: primary

Sylvie PICARD

Role: primary

Isabelle SIMONEAU

Role: primary

Harivola ANDRIANTAOLO

Role: primary

Marie-Agathe TROUVIN

Role: primary

Eva BRIAND

Role: primary

Audrey OLIVETTI

Role: primary

Manal AL MASRI-SHBAT

Role: primary

Chrystel LEPERCHOIS

Role: primary

Charline POTIER

Role: primary

Caroline ARNAUD-SARTHOU

Role: primary

Aude ANGELESCU

Role: primary

Mérédith MERCIER

Role: primary

Samir CHENAF

Role: primary

Sophie GOUNIN

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Optimal-B

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Glycemic Optimization Treatment Study
NCT00552370 COMPLETED PHASE4
A Study in Adults With Type 1 Diabetes
NCT01421147 COMPLETED PHASE3