Gastrectomy at Low Pressure Trial - (GALPT)

NCT ID: NCT07313930

Last Updated: 2026-01-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

74 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-01-10

Study Completion Date

2027-01-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The study is designed to compare two different insufflation devices during surgery, CONMED AirSeal to Lexicon, during Laparoscopic Sleeve Gastrectomy.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

A Single-Center, Prospective, Randomized, Controlled Study Comparing Intraoperative and Perioperative Outcomes using the CONMED AirSeal® and Lexicon Insufflators during Laparoscopic Sleeve Gastrectomy.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pain, Postoperative

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

A Single-Center, Prospective, Randomized, Controlled Study Comparing Intraoperative and Perioperative Outcomes using the CONMED AirSeal® and Lexicon Insufflators during Laparoscopic Sleeve Gastrectomy.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

AirSeal® Insufflation System (AIS)

Use of CONMED AirSeal® during Laparoscopic Sleeve Gastrectomy.

Group Type ACTIVE_COMPARATOR

AirSeal® Insufflation System (AIS)

Intervention Type DEVICE

insufflation device used during laparoscopic sleeve gastrectomy,

Lexicon Insufflator

Use of Lexicon Insufflators during Laparoscopic Sleeve Gastrectomy.

Group Type ACTIVE_COMPARATOR

Lexicon AP 50/30 Insufflator

Intervention Type DEVICE

insufflation device used during laparoscopic sleeve gastrectomy,

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

AirSeal® Insufflation System (AIS)

insufflation device used during laparoscopic sleeve gastrectomy,

Intervention Type DEVICE

Lexicon AP 50/30 Insufflator

insufflation device used during laparoscopic sleeve gastrectomy,

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* . Subject indicated for non-emergent sleeve gastrectomy surgery
* . Subject (or appropriate legal representatives) can provide written informed consent to participate in the study
* Male or Female aged 22 years to 65 years
* Have no significant psychopathology that could limit the subject's ability to understand the procedure, comply with medical, surgical, and/or behavioral recommendations and office visits
* Agree to refrain from any type of elective procedures that would affect body weight such as abdominal lipoplasty or liposuction, mammoplasty, or removal of excess skin for the duration of the trial.
* Are graded as American Society of Anesthesiologists (ASA) Class I, II, or III.

Exclusion Criteria

* Subject participation in a different investigational clinical study within 90 days before screening and for the duration of this trial (unless previously approved by the investigator and Sponsor)
* Subject requiring any surgical procedure in addition to Sleeve Gastrectomy
* Previous malabsorptive or restrictive procedures performed for the treatment of obesity
* Inability to provide informed consent
* Unable or unwilling to attend follow-up visits and examinations
* Uncontrolled hypertension (≥ Systolic: 180 mmHg or Diastolic: ≥ 120 mmHg) and/or diabetes mellitus (Fasting blood sugar level: \>200 mg/dL)
* Subject falls into American Society of Anesthesiologists (ASA) Class ≥ IV
* History of chronic alcohol or drug abuse within 2 years of the screening visit
* Chronic renal failure or on dialysis
* Significant complicating medical history or immunocompromise
* Subject undergoing surgery for malignant disease
* History or presence of pre-existing autoimmune connective tissue disease, e.g., systemic lupus erythematosus or scleroderma
* Immunocompromised, such as that resulting from chronic oral steroid use, chemotherapeutic agents, or immune deficiency disorders
* Any medical condition which precludes compliance with the study
* Subject with any other clinically significant unstable medical disorder, life threatening disease, or conditions that, in the opinion of the investigator, may jeopardize the subject's well-being and/or the soundness of this clinical study or which would contra-indicate a surgical procedure
* Previous or current history of being on regular analgesia / pain killers
* Advanced refusal of blood transfusion, (if necessary)
* If female subject pregnant, planning to become pregnant within 3 months (up to 92 days of procedure), or lactating
Minimum Eligible Age

22 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

SurgiQuest, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Nikhilesh Sekhar, MD FACS FASMBS

Role: PRINCIPAL_INVESTIGATOR

Bariatric and Specialty Surgery Center of Stamford

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Bariatric and Specialty Surgery Center of Stamford

Stamford, Connecticut, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

cynthia Harris, BS

Role: CONTACT

18326776747

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Carolina Castellano, MSN RN AGPCNP-BC

Role: primary

203-610-4075

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

DD1250901

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Endostapler Hemostasis Study
NCT04149925 COMPLETED
ABLATE WEIGHT (Ablation Plus ESG for Weight Loss)
NCT05578703 ACTIVE_NOT_RECRUITING NA