Multilevel Determinants of Socioeconomic Disparities in Geographic Late-Stage Hepatocellular Carcinoma Hotspots

NCT ID: NCT07312162

Last Updated: 2025-12-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

730 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-01-01

Study Completion Date

2027-01-01

Brief Summary

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This study evaluates barriers to early detection of liver cancer.

Detailed Description

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PRIMARY OBJECTIVES:

I. To identify individual-level social and clinical determinants of socioeconomic disparities in late stage Hepatocellular Carcinoma (HCC) burden with a prospective survey of patients with incident HCC. II. To qualitatively explore the multilevel barriers to completion of the early detection pathway for HCC in low socioeconomic status (SES) populations.

OUTLINE: This is an observational study.

Participants complete surveys, have their medical records reviewed, and may complete an interview on study.

Conditions

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Hepatocellular Carcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Observational

Participants complete surveys, have their medical records reviewed, and may complete an interview on study.

Non-Interventional Study

Intervention Type OTHER

Non-interventional study

Interventions

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Non-Interventional Study

Non-interventional study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* \* Adults (18+)

* New diagnosis of HCC
* Able to provide informed consent

Additional criteria:

* Must complete survey
* Residential address in a late stage hotspot
* Medicaid insurance or uninsured
* English, Spanish and Chinese speakers

Exclusion Criteria

* \* Residence outside of Los Angeles County

* Non-HCC liver tumors
* Incarcerated patients
* Pregnant women
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Southern California

OTHER

Sponsor Role lead

National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

National Institute on Minority Health and Health Disparities (NIMHD)

NIH

Sponsor Role collaborator

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kali Zhou

Role: PRINCIPAL_INVESTIGATOR

University of Southern California

Locations

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USC / Norris Comprehensive Cancer Center

Los Angeles, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Kali Zhou

Role: CONTACT

Phone: 323-865-0451

Email: [email protected]

Facility Contacts

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Kali Zhou

Role: primary

Other Identifiers

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NCI-2024-03737

Identifier Type: REGISTRY

Identifier Source: secondary_id

19PS-21-7

Identifier Type: OTHER

Identifier Source: secondary_id

K23MD016963

Identifier Type: NIH

Identifier Source: secondary_id

View Link

P30CA014089

Identifier Type: NIH

Identifier Source: secondary_id

View Link

19PS-21-7

Identifier Type: -

Identifier Source: org_study_id