A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome
NCT ID: NCT07312123
Last Updated: 2025-12-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
84 participants
INTERVENTIONAL
2025-12-08
2027-01-31
Brief Summary
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This clinical study aims to evaluate whether an oral combination of alpha-lipoic acid, Vitamin E, and Vitamin B complex can safely reduce symptoms and improve hand function in patients with Carpal Tunnel Syndrome. These supplements are believed to have antioxidant, anti-inflammatory, and nerve-protective properties, which may help reduce nerve irritation and improve nerve recovery.
Participants in this study will be randomly assigned to receive either the oral supplement combination or a comparator treatment. The study is single-blinded, meaning participants will not know which treatment they are receiving. Symptoms such as pain, numbness, and hand function will be assessed over a defined follow-up period using clinical evaluation and standardized questionnaires.
The main hypothesis of this study is that patients receiving the oral combination of alpha-lipoic acid, Vitamin E, and Vitamin B will experience greater improvement in symptoms and functional outcomes compared to those who do not receive the combination, without significant side effects.
The results of this study may help determine whether this oral supplement combination can be used as an effective and safe conservative treatment option for patients with Carpal Tunnel Syndrome, potentially reducing the need for invasive procedures.
Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Oral Antioxidant Supplement Group
Alpha-Lipoic Acid, Vitamin E, and Vitamin B Complex
An oral dietary supplement containing a combination of alpha-lipoic acid, Vitamin E, and Vitamin B complex administered once daily for the study duration. The supplement is provided in capsule form and is intended to support nerve health through antioxidant and neuroprotective effects in patients with Carpal Tunnel Syndrome.
Control Group
combination vitamin b1,b6 b12
An oral Vitamin B complex supplement administered once daily for the study duration. This intervention serves as the active comparator for conservative treatment of Carpal Tunnel Syndrome.
Interventions
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Alpha-Lipoic Acid, Vitamin E, and Vitamin B Complex
An oral dietary supplement containing a combination of alpha-lipoic acid, Vitamin E, and Vitamin B complex administered once daily for the study duration. The supplement is provided in capsule form and is intended to support nerve health through antioxidant and neuroprotective effects in patients with Carpal Tunnel Syndrome.
combination vitamin b1,b6 b12
An oral Vitamin B complex supplement administered once daily for the study duration. This intervention serves as the active comparator for conservative treatment of Carpal Tunnel Syndrome.
Eligibility Criteria
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Inclusion Criteria
* Subjects with symptoms and physical examination of CTS
* Patients with CTS going for CT release
Exclusion Criteria
* Patients with history of trauma in the dominant hand
18 Years
ALL
No
Sponsors
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Hospital Universiti Sains Malaysia
OTHER
BREGO Life Sciences Sdn Bhd
UNKNOWN
Responsible Party
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NURHAKIM BIN IBRAHIM
medical officer, master student in orthopedic
Principal Investigators
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nurhakim bin ibrahim
Role: PRINCIPAL_INVESTIGATOR
Hospital Pakar Universiti Sains Malaysia
Locations
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Hospital Pakar Universiti Sains Malaysia
Kubang Kerian, Kelantan, Malaysia
Countries
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Central Contacts
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ASSOCIATE PROFESSOR ABDUL NAWFAR BIN SADAGATULLAH
Role: CONTACT
Phone: +6097676378
Email: [email protected]
Facility Contacts
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NURHAKIM BIN IBRAHIM, MEDICAL OFFICER
Role: primary
ASSOCIATE PROFESSOR DR. ABDUL NAWFAR BIN SADAGATULLAH
Role: backup
Other Identifiers
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NMRR ID-25-01261-KS3
Identifier Type: OTHER
Identifier Source: secondary_id
USM/JEPeM/KK/25060535
Identifier Type: -
Identifier Source: org_study_id