Evaluation of Toothbrush Bristles

NCT ID: NCT07306026

Last Updated: 2025-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-21

Study Completion Date

2026-08-31

Brief Summary

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The goal of this randomized clinical trial is to investigate two different types of toothbrush bristles.

The main questions it aims to answer are the effects of two different bristle types on:

* how much plaque is on the teeth
* how deep the space is between gums and teeth
* how much gum and bone are attached to the teeth
* whether the gums bleed when checked
* if the gums get scratched or irritated

Researchers will compare toothbrushes with tapered bristles to those with regular round bristles.

Participants will be randomly assigned toothbrush A or B to use at home during the study.

Detailed Description

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Conditions

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Gingivitis and Periodontal Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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Product A

Product A: Double Tapered J-hook bristles (GUM® Technique® Deep Clean Toothbrush, 525 TPA1)

Group Type OTHER

Toothbrush with tapered bristles

Intervention Type OTHER

Toothbrush with tapered bristles

Product B

End rounded bristles: (GUM® Technique® Deep Clean Toothbrush, 525 TPA1)

Group Type OTHER

Toothbrush with end-rounded bristles

Intervention Type OTHER

Toothbrush with end-rounded bristles

Interventions

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Toothbrush with tapered bristles

Toothbrush with tapered bristles

Intervention Type OTHER

Toothbrush with end-rounded bristles

Toothbrush with end-rounded bristles

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Must have read, understood and signed an informed consent prior to being entered into the study.
* Must be 18 to 70 years of age, male or female.
* Have at least 20 natural or restored teeth, not including implants.
* Must have average Plaque Index of greater than 2 at screening.
* Must have more than 20% of pockets with bleeding on probing at screening.
* Agree not to have a dental prophylaxis or any other elective, non-emergency dental procedures any time during the study.
* Agree to refrain from regular oral hygiene regimen for 24 hours and eating for 4 hours before the appointment in the study.
* Agree to abstain from the use of any dental products other than those provided in the study.
* Agree to comply with the conditions and schedule of the study.

Exclusion Criteria

* Physical limitations or restrictions that might preclude normal tooth brushing.
* Evidence of gross oral pathology
* Periodontal probing pocket depths (PPD) ≥ 5mm.
* Evidence of major soft tissue lesions or trauma at the baseline visit as determined by the examiner.
* Chronic disease with concomitant oral manifestations
* Subjects who are currently undergoing, or require, extensive dental work, orthodontic treatment or periodontal surgery, or orthodontic treatment in the preceding 3 months
* Currently using bleaching trays
* Eating disorders
* Recent history of substance abuse
* Smoking \>10 cigarettes/day
* Participation in other clinical studies within 14 days of screening
* Pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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State University of New York at Buffalo

OTHER

Sponsor Role lead

Responsible Party

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Marcelle Nascimento

Assistant Dean for Clinical Research

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marcelle Nascimento, DDS, MS, PhD

Role: PRINCIPAL_INVESTIGATOR

State University of New York at Buffalo

Locations

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SUNY Buffalo School of Dental Medicine

Buffalo, New York, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Senior Clinical Research Coordinator, Bachelor of Science

Role: CONTACT

Phone: 716-829-6397

Email: [email protected]

Facility Contacts

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Senior Clinical Research Coordinator, Bachelor of Science

Role: primary

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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STUDY00009358

Identifier Type: -

Identifier Source: org_study_id