Two- and Three-Dimensional Quantification of Facial Symmetry After Fat Grafting and Free Flap Reconstruction in Hemifacial Atrophy
NCT ID: NCT07305909
Last Updated: 2025-12-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
60 participants
OBSERVATIONAL
2020-01-10
2023-12-29
Brief Summary
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This is a single-center, retrospective observational study of patients with hemifacial atrophy treated between January 2020 and December 2023 at \[Plastic Surgery Hospital, Chinese Academy of Medical Sciences \& Peking Union Medical College\]. We will quantify facial symmetry before surgery and at the first follow-up visit occurring at or beyond 6 months after the initial surgery. Symmetry outcomes will be assessed using standardized 2D photographs for all included patients, and 3D surface scans for a subset of patients. Complications will also be assessed at the first ≥6-month follow-up visit. We will compare changes in symmetry between patients treated with fat grafting and those treated with free-flap reconstruction.
Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Fat Grafting
Patients with hemifacial atrophy who underwent autologous fat grafting as the initial soft-tissue augmentation procedure. Outcomes were assessed preoperatively and at the first follow-up visit occurring ≥6 months postoperatively.
No interventions assigned to this group
Free Flap Reconstruction (ALT)
Patients with hemifacial atrophy who underwent anterolateral thigh (ALT) free-flap reconstruction as the initial soft-tissue augmentation procedure. Outcomes were assessed preoperatively and at the first follow-up visit occurring ≥6 months postoperatively.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Underwent initial soft-tissue augmentation with either autologous fat grafting or free-flap reconstruction at the study center between January 2020 and December 2023.
Availability of standardized preoperative assessment and postoperative assessment at the first follow-up visit occurring ≥6 months after surgery (2D photographs required).
Exclusion Criteria
Missing key imaging/photographic data required for outcome assessment.
Any additional facial augmentation or revision procedure performed before the first ≥6-month follow-up visit.
ALL
No
Sponsors
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The Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
OTHER
Peking Union Medical College
OTHER
Responsible Party
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Xiaolei Jin
Chief Physician, Professor of Plastic Surgery
Locations
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Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, Beijing Municipality, China
Countries
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Other Identifiers
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2024-344
Identifier Type: OTHER
Identifier Source: secondary_id
2024-344
Identifier Type: -
Identifier Source: org_study_id