Older Adults' Attitudes Towards Stopping Aspirin

NCT ID: NCT07305376

Last Updated: 2025-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

NA

Total Enrollment

2400 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-11-10

Study Completion Date

2026-12-31

Brief Summary

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This online, survey-based experiment will include 2,400 adults who are 65 years and older (n=1,200 each from the United States and Australia). Each participant will be asked to share their opinions on a hypothetical patient scenario developed by our multidisciplinary team. This work is expected to significantly contribute to the understanding of how older adults make decisions about deprescribing medications. The long-term goal is to enhance communication between older adults and clinicians so that medication regimens are optimized and align with care preferences. These results will directly inform future research on the impact of communication choices in clinical practice.

Detailed Description

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Conditions

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Medication Overuse

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

SINGLE

Participants

Study Groups

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Source of recommendation - Physician

Participants read a hypothetical scenario where a doctor recommends stopping aspirin.

Group Type EXPERIMENTAL

Additional harm information

Intervention Type OTHER

Participants received additional information about the harm of continuing aspirin.

Less information

Intervention Type OTHER

Participants will receive less information about the risk of harms of continuing aspirin.

Source of recommendation - Pharmacist

Participants read a hypothetical scenario where a pharmacist recommends stopping aspirin.

Group Type EXPERIMENTAL

Additional harm information

Intervention Type OTHER

Participants received additional information about the harm of continuing aspirin.

Less information

Intervention Type OTHER

Participants will receive less information about the risk of harms of continuing aspirin.

Source of information - AI

Participants read a hypothetical scenario where artificial intelligence is used to recommend stopping aspirin.

Group Type EXPERIMENTAL

Additional harm information

Intervention Type OTHER

Participants received additional information about the harm of continuing aspirin.

Less information

Intervention Type OTHER

Participants will receive less information about the risk of harms of continuing aspirin.

Interventions

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Additional harm information

Participants received additional information about the harm of continuing aspirin.

Intervention Type OTHER

Less information

Participants will receive less information about the risk of harms of continuing aspirin.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Reside in Australia or the United States
* 65 years and older

Exclusion Criteria

* Unable to read survey written in English
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Sydney

OTHER

Sponsor Role collaborator

University of Michigan

OTHER

Sponsor Role lead

Responsible Party

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Sarah Vordenberg

Associate Chair and Clinical Professor Department of Clinical Pharmacy

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sarah Vordenberg, PharmD, MPH

Role: PRINCIPAL_INVESTIGATOR

University of Michigan

Locations

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University of Michigan

Ann Arbor, Michigan, United States

Site Status

Countries

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United States

Other Identifiers

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HUM00280646

Identifier Type: -

Identifier Source: org_study_id