Prevalence of Sarcopenia in Patients Admitted to ICU and Its Progression During Hospitalization.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-05-14

Study Completion Date

2026-02-28

Brief Summary

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This is a prospective, observational study at the ICU of Hospital Mútua de Terrassa, running from May to December 2025. The primary goal is to determine the prevalence of sarcopenia in adult patients requiring more than 48 hours of mechanical ventilation. Sarcopenia is assessed using the SARC-F score, impedanciometry, and quadriceps ultrasound. Secondary aims include tracking the development of ICU-Acquired Weakness (ICU-AW) using the MRC score. All data is collected anonymously after obtaining informed consent.

Detailed Description

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Conditions

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Sarcopenia Critical Illness Intensive Care (ICU) Myopathy Body Composition Measurement Bio-Impedance Measurements Ultrasound Evaluation

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Critically ill adults (medical or surgical) expected to require prolonged mechanical ventilation.

Assesment of the body composition using Rectus Femoris (RF) Ultrasound and Bioelectrical Impedance Analysis (BIA)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Older than 18 years old.
* Expected duration of mechanical ventilation (MV) exceeding 48 hours.

Exclusion Criteria

* Refusal to participate.
* Mechanical ventilation not exceeding 48 hours.
* Do-not-resuscitate (DNR) orders or limitations of therapeutic effort upon admission.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hospital Universitari Mútua Terrassa

Terrassa, Barcelona, Spain

Site Status

Countries

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Spain

References

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Sostakaite G, Jauniskyte M, Budrys D, Budrevicius K, Salciute-Simene E, Svetikiene M, Jovaisa T, Zvirblis T, Klimasauskas A, Sipylaite J. Comparison of Two Techniques to Assess Muscle Mass Loss During ICU Stay: Muscle Ultrasound vs Bioelectrical Impedance Analysis. Nutrition. 2025 Feb;130:112607. doi: 10.1016/j.nut.2024.112607. Epub 2024 Oct 24.

Reference Type BACKGROUND

PMID: 39549651 (View on PubMed)

Nakanishi N, Tsutsumi R, Okayama Y, Takashima T, Ueno Y, Itagaki T, Tsutsumi Y, Sakaue H, Oto J. Monitoring of muscle mass in critically ill patients: comparison of ultrasound and two bioelectrical impedance analysis devices. J Intensive Care. 2019 Dec 16;7:61. doi: 10.1186/s40560-019-0416-y. eCollection 2019.

Reference Type BACKGROUND

PMID: 31890223 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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Mutua Terrassa

Identifier Type: OTHER

Identifier Source: secondary_id

P/25-054/Fundació assistencial

Identifier Type: -

Identifier Source: org_study_id