Preoperative ROX Index and Postoperative Hypoxemia in Bariatric Surgery

NCT ID: NCT07303205

Last Updated: 2025-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-12-25

Study Completion Date

2026-03-01

Brief Summary

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This prospective observational study evaluates whether the preoperative ROX index can predict early postoperative hypoxemia in patients undergoing bariatric surgery. Preoperative ROX measurements, along with ARISCAT and STOP-Bang scores, will be assessed for their association with hypoxemia occurring within the first 12 postoperative hours.

Detailed Description

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Conditions

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Hypoxemia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Preoperative ROX Index Assessment

Participants will undergo a preoperative assessment including measurement of the ROX index (SpO₂/FiO₂ divided by respiratory rate) before bariatric surgery. No treatment or study-related intervention will be applied; all perioperative care will follow routine clinical practice.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adults aged 18-65 years
* Scheduled for elective bariatric surgery (laparoscopic sleeve gastrectomy or Roux-en-Y gastric bypass)
* Body mass index (BMI) ≥ 35 kg/m²
* ASA physical status I-III
* Able and willing to provide written informed consent

Exclusion Criteria

* Acute respiratory failure, pneumonia, or active pulmonary infection
* Receiving oxygen therapy or respiratory support (nasal cannula, CPAP, BiPAP, or high-flow oxygen) preoperatively
* Preoperative SpO₂ \< 88% on room air
* Significant cardiac arrhythmia, severe heart failure (NYHA class III-IV), or hemodynamic instability
* Pregnancy, active malignancy, or current immunosuppressive therapy
* Inability to complete postoperative follow-up or early discharge before 12-hour assessment
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istinye University

OTHER

Sponsor Role lead

Responsible Party

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İlke Dolgun

Assoc. prof

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Istinye Üniversity

Istanbul, Merkez Mahallesi, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Central Contacts

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ilke dolgun

Role: CONTACT

Phone: +905555485632

Email: [email protected]

References

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Helmy MA, Mostafa MS, Saber AT, Ali MA, Milad LM. Erector Spinae Plane Block and its Impact on Postoperative Diaphragmatic Dysfunction in Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy: A Double-Blind Randomized Control Trial. Obes Surg. 2025 Nov 4. doi: 10.1007/s11695-025-08337-y. Online ahead of print.

Reference Type RESULT
PMID: 41188672 (View on PubMed)

Wang X, Guo K, Sun J, Yang Y, Wu Y, Tang X, Xu Y, Chen Q, Zeng S, Wang L, Liu S. Semirecumbent Positioning During Anesthesia Recovery and Postoperative Hypoxemia: A Randomized Clinical Trial. JAMA Netw Open. 2024 Jun 3;7(6):e2416797. doi: 10.1001/jamanetworkopen.2024.16797.

Reference Type RESULT
PMID: 38941098 (View on PubMed)

Lee S, Hong H, Cho H, Lee SW, You AH, Kang HY, Park SW, Kim MK, Choi JH. Association between preoperative oxygen reserve index and postoperative pulmonary complications: a prospective observational study. Korean J Anesthesiol. 2025 Jun;78(3):224-235. doi: 10.4097/kja.24420. Epub 2025 Feb 17.

Reference Type RESULT
PMID: 40468628 (View on PubMed)

Other Identifiers

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erkan rox indeksi

Identifier Type: -

Identifier Source: org_study_id