Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2024-10-01
2025-10-05
Brief Summary
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The study assesses the trajectory of extremity volume difference, early postoperative pain, the recovery pattern of shoulder range of motion and changes in functional status across the first postoperative year. Additionally, it examines the incidence of lymphedema and explores demographic and clinical determinants affecting patient outcomes. The findings are expected to provide evidence for the integration of prehabilitation into standard breast cancer care pathways.
Detailed Description
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The primary focus of the study is to characterize postoperative functional trajectories, including pain intensity, shoulder range of motion (ROM), upper-extremity function, and patient-reported outcomes. Particular emphasis is placed on the early postoperative period, during which pain typically increases and functional limitations become more pronounced. Longitudinal assessments allow observation of recovery patterns across all ROM planes, with anticipated improvements in flexion and abduction by the third postoperative month and further recovery in internal and external rotation by the sixth month.
A secondary objective is to monitor the development of lymphedema, defined by limb volume differences and physical signs of edema. The study also explores demographic and clinical determinants that may influence treatment outcomes, aiming to identify subgroups that benefit most from prehabilitation. By evaluating functional, symptomatic, and quality-of-life outcomes across a 12-month period, this study provides evidence to support the incorporation of preoperative exercise interventions into standard breast cancer care pathways.
Conditions
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Keywords
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Study Design
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NA
SINGLE_GROUP
PREVENTION
NONE
Study Groups
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Prehabilitation Exercise Group
Behavioral Intervention
Prehabilitation Exercise Group
A personalized upper-extremity exercise program initiated before surgery and continued for 12 months postoperatively. The program includes mobility, stretching, strengthening, and functional exercises tailored to individual needs. Instruction is provided through written and visual materials, with follow-up contacts to reinforce adherence.
Interventions
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Prehabilitation Exercise Group
A personalized upper-extremity exercise program initiated before surgery and continued for 12 months postoperatively. The program includes mobility, stretching, strengthening, and functional exercises tailored to individual needs. Instruction is provided through written and visual materials, with follow-up contacts to reinforce adherence.
Eligibility Criteria
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Inclusion Criteria
* Diagnosed with breast cancer and scheduled for surgical treatment
* Able to perform prescribed upper-extremity exercises
* Able to provide informed consent and complete follow-up assessments.
Exclusion Criteria
* Neurological, orthopedic, or systemic conditions limiting upper-extremity mobility
* Prior breast or axillary surgery on the same side
* Planned neoadjuvant chemotherapy that would delay the initiation of the exercise program
* Inability to comply with the exercise instruction or follow-up schedule
18 Years
FEMALE
No
Sponsors
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University of Health Sciences Balikesir Hospital Eduation and Research
OTHER_GOV
Responsible Party
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Mustafa Akin
Associated Professor
Locations
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UHS Balikesir Ataturk Health and Application Center
Balıkesir, , Turkey (Türkiye)
Countries
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References
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Toohey K, Hunter M, McKinnon K, Casey T, Turner M, Taylor S, Paterson C. A systematic review of multimodal prehabilitation in breast cancer. Breast Cancer Res Treat. 2023 Jan;197(1):1-37. doi: 10.1007/s10549-022-06759-1. Epub 2022 Oct 21.
Del Bianco N, Borsati A, Toniolo L, Ciurnielli C, Belluomini L, Insolda J, Sposito M, Milella M, Schena F, Pilotto S, Avancini A. What is the role of physical exercise in the era of cancer prehabilitation? A systematic review. Crit Rev Oncol Hematol. 2024 Jun;198:104350. doi: 10.1016/j.critrevonc.2024.104350. Epub 2024 Apr 18.
Other Identifiers
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UHSBalikesirRadiationOnc
Identifier Type: -
Identifier Source: org_study_id