Trial of the "Mittin" Intervention to Improve Contraceptive Side Effect Counseling and Follow-up in Ethiopia

NCT ID: NCT07301281

Last Updated: 2025-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

2715 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-02-28

Study Completion Date

2027-06-30

Brief Summary

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The goal of this clinical trial is to learn if the "Mittin" intervention can improve women's ability to manage their fertility in line with their preferences among women aged 15-49 using hormonal contraceptives or intrauterine devices and attending public health centers in Addis Ababa, Ethiopia. The main question it aims to answer is: Does the Mittin intervention increase preference-aligned fertility management, contraceptive method satisfaction, and preferred contraceptive method use among participants compared to standard care?

Researchers will compare women's outcomes in health centers providing the Mittin intervention to women's outcomes in health centers that offer standard care to see if Mittin improves women's ability to act in line with their contraceptive preferences.

Participants will

* Receive either standard contraception services (control arm) or enhanced services (intervention arm)
* Participate in a survey at the beginning of the study
* Participate in surveys 4 and 8 months later

Detailed Description

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Conditions

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Contraception Side Effects

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

SINGLE

Investigators
Arm will be masked to the principal investigators until analysis of the primary outcomes at 4 months; prior to this data will be in aggregate form and will not reveal intervention assignment.

Study Groups

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Standard of care arm

Health centers randomized to the standard of care arm will continue offering standard of care contraceptive counseling as per Ethiopian Ministry of Health guidelines. After completion of the c-RCT, the control arm health centers will receive Mittin materials for use on-site (counseling tools, waiting room posters, and educational handouts).

Group Type NO_INTERVENTION

No interventions assigned to this group

Mittin Intervention arm

Health centers randomized to receive the Mittin intervention will receive staff training and materials (counseling tools, waiting room posters, and educational handouts) necessary to offer Mittin's side effects counseling and support model in their facilities. Women enrolled in the study in intervention health centers will receive proactive follow-up calls from call center agents to offer support after initiating a new contraceptive method. The call center will also be available on-demand to any person who desires support related to contraceptive options or side effects.

Group Type EXPERIMENTAL

Mittin

Intervention Type BEHAVIORAL

Mittin intervention consists of the following components:

1. Educational posters and handouts to raise awareness of the right to contraceptive choice and to switch methods if side effects become intolerable
2. Decision support tools for providers to aid women in weighing the risks and benefits of potential side effects during in-person counseling
3. On-demand and proactive virtual side effects counseling and referrals via a call center.

Interventions

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Mittin

Mittin intervention consists of the following components:

1. Educational posters and handouts to raise awareness of the right to contraceptive choice and to switch methods if side effects become intolerable
2. Decision support tools for providers to aid women in weighing the risks and benefits of potential side effects during in-person counseling
3. On-demand and proactive virtual side effects counseling and referrals via a call center.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Woman
* Started or continued using hormonal contraceptive method or copper IUD on day of recruitment
* Ages 15-49 years
* Willing to provide phone number and receive follow-up phone call

Exclusion Criteria

* Not planning to live in Addis Ababa for the next eight months
* Can not verbally communicate
* Not willing to provide consent for the study
Minimum Eligible Age

15 Years

Maximum Eligible Age

49 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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St. Paul's Hospital Millennium Medical College, Ethiopia

OTHER

Sponsor Role collaborator

Bill and Melinda Gates Foundation

OTHER

Sponsor Role collaborator

University of California, San Francisco

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kelsey Holt, ScD

Role: PRINCIPAL_INVESTIGATOR

University of California, San Francisco

Locations

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St. Paul's Hospital Millennium Medical College

Addis Ababa, , Ethiopia

Site Status

Countries

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Ethiopia

Central Contacts

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Kelsey Holt, ScD

Role: CONTACT

Phone: 617-455-2693

Email: [email protected]

Facility Contacts

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Ewenat Gebrehanna, PhD MPH

Role: primary

Hanna Feleke, MPH

Role: backup

Other Identifiers

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INV-044992

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

24-43085

Identifier Type: -

Identifier Source: org_study_id