Tensi+ for Treating Overactive Bladder: A Randomized Controlled Trial

NCT ID: NCT07300904

Last Updated: 2025-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-03-31

Study Completion Date

2027-01-31

Brief Summary

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The purpose of the study is to evaluate the safety and effectiveness of the Tensi+ device using Transcutaneous Posterior Tibial Nerve Stimulation (TPTNS) for treating patients suffering from OAB symptoms urinary frequency, urgency, with or without urge urinary incontinence.

Detailed Description

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Conditions

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Overactive Bladder (OAB)

Keywords

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Overactive Bladder Transcutaneous Tibial Nerve Stimulation Urology

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Tensi+ device to be delivered for use by patient

Group Type ACTIVE_COMPARATOR

Tensi+

Intervention Type DEVICE

Transcutaneous Tibial Nerve Stimulation

Identical Tensi+ Sham device to be delivered for use by patient

Group Type SHAM_COMPARATOR

Tensi+

Intervention Type DEVICE

Transcutaneous Tibial Nerve Stimulation

Interventions

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Tensi+

Transcutaneous Tibial Nerve Stimulation

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult subjects aged 22 years or older and,
* Diagnosed with OAB symptoms (characterized by urinary urgency, with or without UUI),
* Symptoms persisting for at least 3 months, and
* Documented with 2 or more urgency episodes per day (with or without incontinence) in two 3-day bladder diaries and,
* With at least 11 or more voids per day (urinary frequency) documented in two 3-day bladder diaries
* Willing and capable of providing informed consent
* Capable of participating in all testing associated with this clinical investigation

Exclusion Criteria

* Patients with pacemakers or implanted defibrillators or any other implanted electronic device
* Patients prone to excessive bleeding
* Patients with nerve damage that could impact the percutaneous tibial nerve or pelvic floor function
* Patients who are pregnant or planning to become pregnant while using this product
* Patients with ankle joint problems, ankle oedema or dermatological oedema in the area where the electrodes should be placed
* Patients wearing a metal implant near the stimulated area
* Patient with cognitive deficiency
* Administration of intravesical injection of botulinum toxin within 12 months of study enrollment, or treatment within the previous year with other forms neuromodulation for OAB
* Patients treated with medical therapy OAB treatment washout inferior to 30 days
* Patients with diabetic neuropathy
* Patients with uncontrolled diabetes and HbA1c levels above 7%
* Guillain-Barré syndrome
* Chronic inflammatory demyelinating polyneuropathy (CIDP)
* Multiple sclerosis
* A primary diagnosis of stress urinary incontinence (SUI)
* Patients with recurrent rrinary tract infections (UTIs) defined as more than 2 episodes per year, or with any baseline lower urinary tract pathology identified at the time of the 3-day bladder diary assessment.
* Currently participating in another clinical trial
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Stimuli Technology

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Cedars-Sinai

Beverly Hills, California, United States

Site Status

NYU Langone Health

New York, New York, United States

Site Status

Toronto Western Hospital

Toronto, , Canada

Site Status

Countries

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United States Canada

Central Contacts

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Akshaya Mariadassou

Role: CONTACT

Phone: +331 84 60 48 25

Email: [email protected]

Sarah Todeschini

Role: CONTACT

Phone: +331 84 60 48 25

Email: [email protected]

Facility Contacts

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Karyn Eilber

Role: primary

Benjamin Brucker

Role: primary

Dean Elterman

Role: primary

Other Identifiers

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CIP-PF0001-02

Identifier Type: -

Identifier Source: org_study_id