Blocking Sphenopalatine Ganglion by Intranasal Lidocaine Spray in Partial Turbinectomy Surgeries
NCT ID: NCT07299630
Last Updated: 2025-12-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE3
50 participants
INTERVENTIONAL
2025-12-20
2026-02-01
Brief Summary
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Detailed Description
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Usually the surgery is done as a day case surgery in patients without major comorbidities. Points of concern to achieve smooth outcome and enhance recovery include pain management, better surgical field for both patient and surgeon satisfaction. One approach for these goals include regional nerve blocks for the innervation of the nose .
Spheno Palatine Ganglion (SPG) block was tested with a good results for blocking autonomic innervation and subsequent decrease in pain and opioid consumption. Blockage of SPG has many approaches either trans nasal or trans oral but both are invasive and needs trained hands to do Locally infiltrating lidocaine over nasal mucosa either by lidocaine spray or a lidocaine soaked gauze was also tested in nasal surgeries with good results but doubts about duration of action of lidocaine spray is a concern that may affect post-operative pain management Targeting SPG noninvasively by lidocaine spray is proposed technique that may offer easier approach for this type of surgeries. Although concerns about effectiveness of the spray to reach and block SPG was raised before , many studies examined this approach to control headache or trigeminal neuralgia with great success.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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balanced anaesthesia
Analgesia will be offered by fentanyl in induction according to Actual Body Weight (ABW). and morphine after intubation
Balanced anesthesia
Analgesia will be offered by fentanyl in induction according to Actual Body Weight (ABW). and morphine after intubation
Lidocaine spray
o Analgesia will be offered by fentanyl in induction according to Actual Body Weight (ABW) and then Lignocaine spray 10% 10 puffs will be applied on to the nasal cavity after directing the spray applicator parallel to the nasal floor until resistance is felt after intubation and application of nasal decongestant, in the two nostrils
Lidocaine spray
o Analgesia will be offered by fentanyl in induction according to Actual Body Weight (ABW) and then Lignocaine spray 10% 10 puffs will be applied on to the nasal cavity after directing the spray applicator parallel to the nasal floor until resistance is felt after intubation and application of nasal decongestant, in the two nostrils
Interventions
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Balanced anesthesia
Analgesia will be offered by fentanyl in induction according to Actual Body Weight (ABW). and morphine after intubation
Lidocaine spray
o Analgesia will be offered by fentanyl in induction according to Actual Body Weight (ABW) and then Lignocaine spray 10% 10 puffs will be applied on to the nasal cavity after directing the spray applicator parallel to the nasal floor until resistance is felt after intubation and application of nasal decongestant, in the two nostrils
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Kidney or liver impairment
* Pregnant or breast-feeding women
* Allergy to any of the drugs used in the study
* OR time more than 90 min
18 Years
ALL
No
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Locations
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Ain shams university hospitals
Cairo, , Egypt
Countries
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Central Contacts
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Facility Contacts
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Abdallah soudi, M.D.
Role: primary
Other Identifiers
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FMASU R239/2025
Identifier Type: -
Identifier Source: org_study_id