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Effects of the Dietary Inflammatory Index on Systemic Inflammation Markers and Gastrointestinal Symptoms in Individuals With Bariatric Surgery

NCT ID: NCT07293624

Last Updated: 2025-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

70 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-12-01

Study Completion Date

2026-07-30

Brief Summary

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The goal of this observational cross-sectional study is to evaluate the relationships between the Dietary Inflammatory Index (DII), systemic inflammatory markers, and gastrointestinal symptoms in adults aged 18-65 who have undergone bariatric surgery.

The main questions it aims to answer are:

Does the inflammatory potential of the diet affect systemic inflammation levels (such as SII, CRP, and WBC) in the post-operative period?

Is there an association between the DII score and gastrointestinal symptoms (e.g., bloating, gas, abdominal pain)?

Participants who are at least three months post-bariatric surgery will provide dietary intake data to calculate DII scores, undergo blood tests to measure inflammatory markers, and complete assessments regarding their gastrointestinal symptoms.

Detailed Description

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Conditions

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Bariatric Surgery Bariatric Sleeve Gastrectomy Inflamation Systemic Inflammation Dietary Inflammatory Index (DII) Systemic Inflammation Markers

Keywords

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sleeve gastrectomy diatary inflammation bariatric surgery systemic inflammation

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Interventions

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Observational Intervention

This is cross sectional observational study.

Intervention Type OTHER

Observetional

This is cross-sectional study. Questionnaire, Dietary Inflammatory Index (DII), systemic inflammatory markers, and gastrointestinal symptoms will be investigated.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adult individuals between the ages of 18 and 65,
* Having undergone bariatric surgery at least 3 months prior,
* Individuals who agreed to participate voluntarily in the study and signed the informed consent form,
* Having the cognitive ability/literacy to completely complete the food consumption record and questionnaire forms,
* Individuals with no health conditions that would prevent blood tests,
* Individuals who were regularly followed up after surgery and had no postoperative complications.

Exclusion Criteria

* Individuals diagnosed with gastrointestinal diseases such as inflammatory bowel disease, celiac disease, or short bowel syndrome before or after bariatric surgery,
* Those with a history of diseases that could affect systemic inflammation, such as autoimmune disease, active infection, or cancer,
* Individuals regularly taking medications that could affect inflammation levels, such as corticosteroids, immunosuppressants, or anti-inflammatory drugs,
* Individuals actively or recently using probiotic supplements,
* Pregnant or breastfeeding women,
* Those with a history of chronic alcohol use or substance abuse,
* Individuals who experienced serious postoperative complications after surgery (e.g., anastomotic leak, serious infection, or conditions requiring reoperation),
* Individuals with cognitive or communication disabilities that prevented them from providing the necessary information and data to the study or who were lost to follow-up,
* Individuals with chronic organ failure,
* Individuals with a psychiatric diagnosis,
* Individuals who did not consent to their data being used for scientific purposes.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istanbul Bilgi University

OTHER

Sponsor Role lead

Responsible Party

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Hande Seven Avuk

Assistant Professor, Head of Nutrition and Dietetic Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hande Seven Avuk, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Istanbul Bilgi University

Gökben Anıl

Role: PRINCIPAL_INVESTIGATOR

Haliç University

Locations

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Istanbul Bilgi University

Istanbul, Uskudar, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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BARINFLAMMATION

Identifier Type: -

Identifier Source: org_study_id