Legs Exercises and Compression Stockings for Prevention of Hemodialysis Muscle Cramps
NCT ID: NCT07293182
Last Updated: 2025-12-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
108 participants
INTERVENTIONAL
2025-12-25
2026-06-20
Brief Summary
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1. Investigate the effect of legs exercises in the prevention of muscle cramps among hemodialysis patients.
2. Examine the effect of compression stockings in the prevention of muscle cramps among hemodialysis patients.
3. Compare between effect of legs exercises and compression stockings in the prevention of muscle cramps among hemodialysis patients.
4. Find out the relationship between the effect of legs exercises and compression stockings in the prevention of muscle cramps with patients' demographic and clinical data.
Detailed Description
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Most methods for relieving muscle cramp pain have been pharmacological; however, these often elevate the risk of drug toxicity since the kidneys primarily excrete the metabolites of these drugs. This study investigates the effects of leg exercises and compression stockings on the prevention of leg cramps. These intervention methods have been less commonly utilized and have predominantly been explored in small patient populations. this research will provide insights into the effectiveness of these approaches and contribute to the development of improved prevention strategies.
When a dialysis patient exercises, the leg muscles signal the brain to increase blood flow to provide the necessary energy for activity . Exercise during dialysis positively impacts urea clearance by enhancing tissue exposure and opening blood vessels in the working muscles, allowing fluids within the tissues to flow into the intravascular space. Furthermore, ions such as potassium and phosphate move from the intracellular space into the muscle interstitial fluid during exercise, improving blood flow to the muscles and alleviating pain in these patients .
The use of graduated compression stockings applies a pressure gradient that ensures blood flows upward toward the heart rather than backing up toward the feet or sideways into the superficial veins. This application of an appropriate pressure gradient reduces the diameter of major veins, increasing the velocity and volume of blood flow. Gradient compression can effectively reverse elevated venous blood pressure, enhance skeletal muscle pumping, facilitate venous return, and improve lymphatic drainage.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
Participants in the Compression Stockings Group: apply Compression stockings for 30 minutes from the end of the second hour to the beginning of the third hour of hemodialysis session once per session and the same was repeated for 3 such session , participants in the control group receive standard hemodialysis without legs exercises and compression stockings modalities.
PREVENTION
NONE
Study Groups
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legs exercises group
participants in the Legs Exercises Group were trained to use a mini stationary bike in a supine position for 30 minute from the end of the second hour to the beginning of the third hour of hemodialysis session once per session and the same was repeated for 3 such session . The exercise was performed under the supervision of a trained nurse.
legs exercises
participants in the Legs Exercises Group were trained to use a mini stationary bike in a supine position for 30 minute from the end of the second hour to the beginning of the third hour of hemodialysis session once per session and the same was repeated for 3 such session . The exercise was performed under the supervision of a trained nurse.
compression stockings group
Participants in the Compression Stockings Group: apply Compression stockings for 30 minutes from the end of the second hour to the beginning of the third hour of hemodialysis session once per session and the same was repeated for 3 such session .
compression stockings
Participants in the Compression Stockings Group: apply Compression stockings for 30 minutes from the end of the second hour to the beginning of the third hour of hemodialysis session once per session and the same was repeated for 3 such session .
control group
participants in the control group receive standard hemodialysis without legs exercises and compression stockings modalities.
No interventions assigned to this group
Interventions
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legs exercises
participants in the Legs Exercises Group were trained to use a mini stationary bike in a supine position for 30 minute from the end of the second hour to the beginning of the third hour of hemodialysis session once per session and the same was repeated for 3 such session . The exercise was performed under the supervision of a trained nurse.
compression stockings
Participants in the Compression Stockings Group: apply Compression stockings for 30 minutes from the end of the second hour to the beginning of the third hour of hemodialysis session once per session and the same was repeated for 3 such session .
Eligibility Criteria
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Inclusion Criteria
* Both genders (male \& female).
* Undergoing regular hemodialysis.
* Patients who are conscious and cooperative.
* Patients experiencing muscle cramps during hemodialysis session.
* Patients who would like to participate in part in the study .
* Patients with verbally communicated skills.
Exclusion Criteria
* Presence of femoral catheters
* Any lower limb pathology or musculoskeletal impairments
* Patients undergoing emergency or first-time hemodialysis
* Pilot study participants.
* Patients decline to take part in the trial.
* Patients who are unable to tolerate the exercises and compression stockings .
18 Years
70 Years
ALL
No
Sponsors
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Karbala University
OTHER
Responsible Party
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Zahraa Adel Kareem
Master's graduate student
Principal Investigators
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zahraa A Kareem, MGS
Role: PRINCIPAL_INVESTIGATOR
kerbala heath department
Central Contacts
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Other Identifiers
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UOK.CON.25.091
Identifier Type: -
Identifier Source: org_study_id