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The Effect of Low Intensity With BFR on Stroke Patients

NCT ID: NCT07292675

Last Updated: 2025-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-12-13

Study Completion Date

2026-05-13

Brief Summary

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To compare the effects of low-intensity resistance training with blood flow restriction (BFR) versus traditional resistance training on lower limb isokinetic torque and dynamic balance in ischemic stroke survivors.

Detailed Description

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Ischemic stroke commonly results in reduced lower extremity muscle torque and impaired balance, affecting mobility and fall risk.

Traditional resistance training improves muscle function but may not be suitable for all patients due to the need for high mechanical loads.

Low-intensity resistance training with blood flow restriction (BFR) has emerged as an alternative that enhances muscular adaptation at lower loads. However, limited data exists on its effect on isokinetic torque and functional balance in stroke patients. This study aims to fill this gap using objective isokinetic measurements and validated balance scales.

Conditions

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Ischemic Stroke

Keywords

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BFR , Stroke

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Groups:

* Group A: Low-intensity BFR resistance training
* Group B: Traditional resistance training
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
The patients in control group will receive high intensity resistance training

Study Groups

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Study group

Study group will receive low-intensity BFR resistance training

Group Type EXPERIMENTAL

low-intensity resistance training with blood flow restriction

Intervention Type OTHER

"Low-Intensity" BFR Means (for Quads)

It involves resistance 20-30% 1RM combined with partial arterial + full venous restriction using a cuff placed on the proximal thigh.

Control group

Control group will receive high intensity resistance training

Group Type ACTIVE_COMPARATOR

High intensity resistance training

Intervention Type OTHER

High-intensity quadriceps training in stroke patients focuses on using 60-80% of 1RM to improve strength, motor unit recruitment, and functional mobility. Exercises such as loaded sit-to-stand, leg press, and step-ups are commonly used to target the quadriceps safely. Training intensity is guided by a perceived exertion of 7-9/10 while maintaining proper supervision to prevent falls. This approach enhances knee stability, gait efficiency, and overall functional independence.

Interventions

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low-intensity resistance training with blood flow restriction

"Low-Intensity" BFR Means (for Quads)

It involves resistance 20-30% 1RM combined with partial arterial + full venous restriction using a cuff placed on the proximal thigh.

Intervention Type OTHER

High intensity resistance training

High-intensity quadriceps training in stroke patients focuses on using 60-80% of 1RM to improve strength, motor unit recruitment, and functional mobility. Exercises such as loaded sit-to-stand, leg press, and step-ups are commonly used to target the quadriceps safely. Training intensity is guided by a perceived exertion of 7-9/10 while maintaining proper supervision to prevent falls. This approach enhances knee stability, gait efficiency, and overall functional independence.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* • First-ever ischemic stroke (3-12 months post-stroke)

* Aged 30-40 years
* Can walk independently or with an aid
* Medically stable and able to follow instructions

Exclusion Criteria

* •Hemorrhagic stroke

* Deep vein thrombosis or peripheral vascular disease
* Orthopedic conditions affecting lower limb
* Severe cognitive impairment or uncontrolled hypertension
Minimum Eligible Age

30 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Delta University for Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Ibrahim Ahmed Ibrahim Abu Ella

lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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ibrahim A abu ella, Phd

Role: CONTACT

Phone: +201008442281

Email: [email protected]

Other Identifiers

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P.T.REC/012/005961

Identifier Type: -

Identifier Source: org_study_id