Clinical Trial Comparing Pain Perception in Children Using Two Different Local Anesthesia Tools

NCT ID: NCT07292194

Last Updated: 2025-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-01-01

Study Completion Date

2026-04-01

Brief Summary

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The goal of this clinical study is to learn whether the Super Pen (SP) device can reduce pain during local anesthesia (LA) infiltration for primary teeth compared to the conventional syringe (CS) in children aged 6-12 years. It will also explore factors that influence children's pain perception and their preferences for the anesthesia delivery method.

The main questions this study aims to answer are:

* Does the Super Pen (SP) reduce the pain experienced during LA infiltration compared to the conventional syringe (CS)?
* How do factors such as age, sex, and arch treated (maxilla or mandible) influence children's pain perception when using the SP?
* Which method-SP or CS-do children prefer during LA infiltration?

Participants will:

Receive local anesthesia using both the SP and CS techniques in a split-mouth design.

Have their pain responses assessed using self-reported, behavioral, and physiological measures.

Indicate their preference for either technique after both experiences.

Detailed Description

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This clinical study aims to evaluate and compare the pain perception of pediatric patients aged 6-12 years during local anesthetic (LA) infiltration for primary teeth using the Computer-Controlled Local Anesthetic Delivery (CCLAD) system-Super Pen (SP)-versus the Conventional Syringe (CS) technique. The study follows a split-mouth crossover design, in which each child receives anesthesia using both techniques in separate appointments, allowing for direct within-subject comparison.

Pain assessment will be conducted using a combination of self-reported, behavioral, and physiological measures: the Faces Pain Scale-Revised (FPS-R), the revised Face, Legs, Activity, Cry, Consolability (r-FLACC) behavioral pain scale, and heart rate monitoring. These multiple pain measures used provide a comprehensive evaluation of the child's pain experience.

The study will also investigate the influence of age, sex, and anatomical site (maxilla or mandible) on pain perception during SP administration. In addition, children's preferences for the two delivery systems (SP versus CS) will be recorded after both experiences to assess acceptance and comfort.

The findings of this research aim to contribute to improving pain management strategies in pediatric dentistry, supporting the use of more comfortable and child-friendly anesthesia delivery systems to enhance the dental experience and reduce anxiety in young patients.

Conditions

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Injection Pain Local Anesthesia Infiltration Pediatric Patient

Keywords

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clinical trial split mouth dental pain local anesthesia device local anesthesia infiltration

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Super Pen

Super Pen Computer-controlled Local Anesthesia delivery system

Group Type ACTIVE_COMPARATOR

super pen

Intervention Type DEVICE

computer controlled local anesthesia delivery device

Conventional Syringe

Conventional metal syringe

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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super pen

computer controlled local anesthesia delivery device

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Children who were 6-12 years of age, of both sexes.
2. Children who were healthy and medically fit; ASA I .
3. Children who had positive (Class 3) or definitely positive (Class 4) behavior during preoperative behavioral assessments according to the Frankl Scale at the enrollment visit.
4. Children who require bilateral LA infiltration injections for primary teeth, either in the maxilla or mandible, for dental treatment (different types of restoration, stainless steel crowns, pulp therapy, and extractions).
5. Children with positive consent forms approved by their parents/ legal guardians.

Exclusion Criteria

1. Children who have had a history of unpleasant experiences in medical settings and/or LA injection procedures.
2. Children with any mental, visual, or auditory impairment.
3. Children who have medical or developmentally compromising conditions.
4. Children who had developmental delay problems.
5. Children with a history of chronic disease or use of medication that contraindicate the use of local anesthetics.
6. Children who had active pathosis at the injection site that could affect anesthetic assessment.
7. Patients who have negative (Class 2) or definitely negative (Class 1) behavior during preoperative behavioral assessments according to the Frankl Scale . - -
Minimum Eligible Age

6 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Lamis D. Rajab

OTHER

Sponsor Role lead

Responsible Party

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Lamis D. Rajab

professor

Responsibility Role SPONSOR_INVESTIGATOR

Central Contacts

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lamis D Rajab, Professor

Role: CONTACT

Phone: +962795616651

Email: [email protected]

Other Identifiers

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UJordanLamis2

Identifier Type: -

Identifier Source: org_study_id