To Compare the Clinical Outcomes of FemtoLASIK and ICL Implantation in Treating Moderate Myopia Focusing on Refractive Stability, Contrast Sensitivity and High Order Aberrations.

NCT ID: NCT07291986

Last Updated: 2025-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-01

Study Completion Date

2025-05-06

Brief Summary

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Compare the clinical outcomes of FemtoLASIK and ICL implantation in treating moderate myopia.

Detailed Description

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The clinical outcomes of FemtoLASIK and ICL implantation focusing on refractive stability, contrast sensitivity and high order aberrations.

Conditions

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Myopia, Moderate

Keywords

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FemtoLASIK, ICL, myopia, HOA, contrast sensitivity

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Simple Myopic Patients

Patients with simple myopia undergoing FemtoLASIK or ICL surgeries

Group Type ACTIVE_COMPARATOR

FemtoLASIK

Intervention Type PROCEDURE

FemtoLASIK surgery for simple and compound myopic patients

ICL implantation

Intervention Type PROCEDURE

ICL implantation for simple and compound myopic patients

Compound Myopic Patients

Patients with compound myopia undergoing FemtoLASIK or ICL surgeries

Group Type ACTIVE_COMPARATOR

FemtoLASIK

Intervention Type PROCEDURE

FemtoLASIK surgery for simple and compound myopic patients

ICL implantation

Intervention Type PROCEDURE

ICL implantation for simple and compound myopic patients

Interventions

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FemtoLASIK

FemtoLASIK surgery for simple and compound myopic patients

Intervention Type PROCEDURE

ICL implantation

ICL implantation for simple and compound myopic patients

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

Group I - FemtoLASIK subgroup:

* Age range: 21-40 years.
* Stable myopia for at least one year (refractive change

≤ 0.50 D).
* Spherical equivalent between -4.00 D and -8.00 D.
* Corneal thickness ≥ 500 μm, residual stromal bed \> 300 μm and percentage of tissue altered \< 39%.
* No evidence of keratoconus or ectatic changes on corneal topography/tomography.
* Mesopic pupil diameter ≤ 6.5 mm.
* Absence of ocular surface disease or significant dry eye symptoms.
* No history of prior ocular surgery or trauma.

Group II - ICL subgroup:

* Age range: 21-40 years.
* Stable myopia (with or without astigmatism) for ≥1 year.
* Spherical equivalent between -4.00 D and -8.00 D.
* Anterior chamber depth ≥ 2.8 mm from endothelium.
* Endothelial cell density ≥ 2500 cells/mm².
* White-to-white and sulcus-to-sulcus diameters suitable for ICL sizing.
* Clear crystalline lens with no signs of early cataract.
* No history of intraocular surgery, uveitis, or glaucoma.

Exclusion Criteria

Patients with mild myopia (\<-4D) or high myopia (\>- 8D) or hyperopia.

* Patients with media opacity.
* Patients with associated ocular pathology.
* Patients with corneal topography not fitting to either treatment modalities.
Minimum Eligible Age

21 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Walid Osama Abdel Rahman Nour El Din

OTHER

Sponsor Role lead

Responsible Party

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Walid Osama Abdel Rahman Nour El Din

Cornea and Refractive Ophthalmology Consultant

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Omar M Said, MD

Role: STUDY_DIRECTOR

Faculty of Medicine, Fayoum University

Locations

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Faculty of Medicine, Fayoum University

Al Fayyum, , Egypt

Site Status

Countries

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Egypt

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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D261

Identifier Type: -

Identifier Source: org_study_id