Serum Hyperbilirubinemia as an Early Predictive Factor for Complicated Appendicitis: Single Center Experience

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-01

Study Completion Date

2025-08-20

Brief Summary

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Serum total bilirubin provides a practical guide to early assessment of suspected appendicitis, supporting faster and more proportionate decisions-earlier escalation when overall risk is high and safe observation when it is low. Because testing is rapid, inexpensive, and universally available, integration into local diagnostic pathways is feasible.

Detailed Description

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Conditions

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Appendicitis, Surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Simple appendicitis ( group A)

Patients where no perforation, gangrene, or other complications were found during surgery.

Appendectomy

Intervention Type PROCEDURE

Total bilirubin levels was measured preoperatively as part of the routine laboratory workup. Appendectomy done for all patients followed by histopathological evaluation of the excised appendix.

Complicated appendicitis (group B)

• Complicated appendicitis group (B): Patients who presented with perforation or gangrene, confirmed via operative findings and histopathological examination.

Total bilirubin levels was measured preoperatively as part of the routine laboratory workup.

Appendectomy

Intervention Type PROCEDURE

Total bilirubin levels was measured preoperatively as part of the routine laboratory workup. Appendectomy done for all patients followed by histopathological evaluation of the excised appendix.

Interventions

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Appendectomy

Total bilirubin levels was measured preoperatively as part of the routine laboratory workup. Appendectomy done for all patients followed by histopathological evaluation of the excised appendix.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All patients presented with right iliac fossa pain diagnosed clinically as acute appendicitis and had undergone appendectomy

Exclusion Criteria

* patients with past history of jaundice
* patients with history of hyperbilirubinemia hemolytic disease
* positive hepatitis viruses
* cholelithiasis
* acquired or congenital biliary disease
* cancer of the hepatobiliary system

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Asaad AbdelRahman AbdelAziz Ahmad

Director and lecturer of general surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Minia university

Minya, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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